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Large language models (LLMs) hold considerable potential for advancing scientific discovery, yet systematic assessment of their dynamic reasoning in real-world research remains limited. Current scientific evaluation benchmarks predominantly…

Computation and Language · Computer Science 2026-03-27 Taolin Han , Shuang Wu , Jinghang Wang , Yuhao Zhou , Renquan Lv , Bing Zhao , Wei Hu

Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy…

Artificial Intelligence · Computer Science 2026-01-06 Udiptaman Das , Krishnasai B. Atmakuri , Duy Ho , Chi Lee , Yugyung Lee

Conventional biomedical research is increasingly labor-intensive due to the exponential growth of scientific literature and datasets. Artificial intelligence (AI), particularly Large Language Models (LLMs), has the potential to…

Multiagent Systems · Computer Science 2025-07-08 Yi Luo , Linghang Shi , Yihao Li , Aobo Zhuang , Yeyun Gong , Ling Liu , Chen Lin

Language agents have recently been used to simulate human behavior and user-item interactions for recommendation systems. However, current language agent simulations do not understand the relationships between users and items, leading to…

Artificial Intelligence · Computer Science 2025-01-28 Taicheng Guo , Chaochun Liu , Hai Wang , Varun Mannam , Fang Wang , Xin Chen , Xiangliang Zhang , Chandan K. Reddy

Entity alignment (EA) aims to identify entities across different knowledge graphs (KGs) that refer to the same real-world object and plays a critical role in knowledge fusion and integration. Traditional EA methods mainly rely on knowledge…

Information Retrieval · Computer Science 2026-04-14 Yixuan Nan , Xixun Lin , Yanmin Shang , Ge Zhang , Zheng Fang , Fang Fang , Yanan Cao

We envision "AI scientists" as systems capable of skeptical learning and reasoning that empower biomedical research through collaborative agents that integrate AI models and biomedical tools with experimental platforms. Rather than taking…

AI models underpin data-centric applications from image and text processing to scientific discovery in biology, physics, and chemistry. Yet developing them remains heavily manual, requiring practitioners to design architectures, build…

Artificial Intelligence · Computer Science 2026-05-28 Ruiyi Zhang , Peijia Qin , Qi Cao , Li Zhang , Pengtao Xie

Fully automated self-driving laboratories are promising to enable high-throughput and large-scale scientific discovery by reducing repetitive labour. However, effective automation requires deep integration of laboratory knowledge, which is…

Artificial Intelligence · Computer Science 2025-09-30 Shuxiang Cao , Zijian Zhang , Mohammed Alghadeer , Simone D Fasciati , Michele Piscitelli , Mustafa Bakr , Peter Leek , Alán Aspuru-Guzik

Large Language Models (LLMs) show promise in biomedicine but lack true causal understanding, relying instead on correlations. This paper envisions causal LLM agents that integrate multimodal data (text, images, genomics, etc.) and perform…

Artificial Intelligence · Computer Science 2025-05-23 Adib Bazgir , Amir Habibdoust Lafmajani , Yuwen Zhang

The advances made by Large Language Models (LLMs) have led to the pursuit of LLM agents that can solve intricate, multi-step reasoning tasks. As with any research pursuit, benchmarking and evaluation are key corner stones to efficient and…

Artificial Intelligence · Computer Science 2024-04-10 Luca Gioacchini , Giuseppe Siracusano , Davide Sanvito , Kiril Gashteovski , David Friede , Roberto Bifulco , Carolin Lawrence

Large-scale Language Models (LLMs) have revolutionized human-AI interaction and achieved significant success in the generation of novel ideas. However, current assessments of idea generation overlook crucial factors such as knowledge…

Artificial Intelligence · Computer Science 2025-05-27 Yansheng Qiu , Haoquan Zhang , Zhaopan Xu , Ming Li , Diping Song , Zheng Wang , Kaipeng Zhang

We introduce SciQAG, a novel framework for automatically generating high-quality science question-answer pairs from a large corpus of scientific literature based on large language models (LLMs). SciQAG consists of a QA generator and a QA…

Computation and Language · Computer Science 2024-07-11 Yuwei Wan , Yixuan Liu , Aswathy Ajith , Clara Grazian , Bram Hoex , Wenjie Zhang , Chunyu Kit , Tong Xie , Ian Foster

We introduce AInsteinBench, a large-scale benchmark for evaluating whether large language model (LLM) agents can operate as scientific computing development agents within real research software ecosystems. Unlike existing scientific…

Developing accurate biomedical Question Answering (QA) systems in low-resource languages remains a major challenge, limiting equitable access to reliable medical knowledge. This paper introduces BanglaMedQA and BanglaMMedBench, the first…

Computation and Language · Computer Science 2025-11-07 Sadia Sultana , Saiyma Sittul Muna , Mosammat Zannatul Samarukh , Ajwad Abrar , Tareque Mohmud Chowdhury

We introduce Meta MLGym and MLGym-Bench, a new framework and benchmark for evaluating and developing LLM agents on AI research tasks. This is the first Gym environment for machine learning (ML) tasks, enabling research on reinforcement…

The rapid growth of AI agent ecosystems is transforming how complex tasks are delegated and executed, creating a new challenge of identifying suitable agents for a given task. Unlike traditional tools, agent capabilities are often…

Artificial Intelligence · Computer Science 2026-04-27 Bin Wu , Arastun Mammadli , Xiaoyu Zhang , Emine Yilmaz

A key challenge in artificial intelligence is the creation of systems capable of autonomously advancing scientific understanding by exploring novel domains, identifying complex patterns, and uncovering previously unseen connections in vast…

Artificial Intelligence · Computer Science 2024-09-10 Alireza Ghafarollahi , Markus J. Buehler

We introduce MLRC-Bench, a benchmark designed to quantify how effectively language agents can tackle challenging Machine Learning (ML) Research Competitions, with a focus on open research problems that demand novel methodologies. Unlike…

While Retrieval-Augmented Generation (RAG) has been swiftly adopted in scientific and clinical QA systems, a comprehensive evaluation benchmark in the medical domain is lacking. To address this gap, we introduce the Medical…

Computation and Language · Computer Science 2026-02-12 Liz Li , Wei Zhu

Health informatics research is characterized by diverse data modalities, rapid knowledge expansion, and the need to integrate insights across biomedical science, data analytics, and clinical practice. These characteristics make it…

Artificial Intelligence · Computer Science 2025-09-24 Yuxiao Cheng , Jinli Suo