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The code written by developers usually suffers from efficiency problems and contain various performance bugs. These inefficiencies necessitate the research of automated refactoring methods for code optimization. Early research in code…

Software Engineering · Computer Science 2024-08-23 Shuzheng Gao , Cuiyun Gao , Wenchao Gu , Michael Lyu

Machine learning (ML) is transforming modeling and control in the physical, engineering, and biological sciences. However, rapid development has outpaced the creation of standardized, objective benchmarks - leading to weak baselines,…

Performance of Large Language Models (LLMs) on multiple-choice tasks differs markedly between symbol-based and cloze-style evaluation formats. The observed discrepancies are systematically attributable to task characteristics: natural…

Computation and Language · Computer Science 2026-02-02 Joonhak Lee , Sungmok Jung , Jongyeon Park , Jaejin Lee

Deep Metric Learning (DML) is arguably one of the most influential lines of research for learning visual similarities with many proposed approaches every year. Although the field benefits from the rapid progress, the divergence in training…

Computer Vision and Pattern Recognition · Computer Science 2020-08-04 Karsten Roth , Timo Milbich , Samarth Sinha , Prateek Gupta , Björn Ommer , Joseph Paul Cohen

To facilitate widespread adoption of automated engineering design techniques, existing methods must become more efficient and generalizable. In the field of topology optimization, this requires the coupling of modern optimization methods…

Computational Engineering, Finance, and Science · Computer Science 2024-02-23 Connor N. Mallon , Aaron W. Thornton , Matthew R. Hill , Santiago Badia

In multi-task Bayesian optimization, the goal is to leverage experience from optimizing existing tasks to improve the efficiency of optimizing new ones. While approaches using multi-task Gaussian processes or deep kernel transfer exist, the…

Purpose: This study aimed to enhance protein sequence classification using natural language processing (NLP) techniques while addressing the impact of sequence similarity on model performance. We compared various machine learning and deep…

Quantitative Methods · Quantitative Biology 2025-05-26 Huma Perveen , Julie Weeds

Optimization modeling plays a critical role in the application of Operations Research (OR) tools to address real-world problems, yet they pose challenges and require extensive expertise from OR experts. With the advent of large language…

Computation and Language · Computer Science 2025-07-30 Chenyu Huang , Zhengyang Tang , Shixi Hu , Ruoqing Jiang , Xin Zheng , Dongdong Ge , Benyou Wang , Zizhuo Wang

We present LS-CRF, a new method for very efficient large-scale training of Conditional Random Fields (CRFs). It is inspired by existing closed-form expressions for the maximum likelihood parameters of a generative graphical model with tree…

Machine Learning · Computer Science 2014-03-28 Alexander Kolesnikov , Matthieu Guillaumin , Vittorio Ferrari , Christoph H. Lampert

Clinical trial eligibility matching is a critical yet often labor-intensive and error-prone step in medical research, as it ensures that participants meet precise criteria for safe and reliable study outcomes. Recent advances in Natural…

Machine Learning · Computer Science 2025-03-04 Muhammad Talha Sharif , Abdul Rehman

Recently, supervised hashing methods have attracted much attention since they can optimize retrieval speed and storage cost while preserving semantic information. Because hashing codes learning is NP-hard, many methods resort to some form…

Machine Learning · Computer Science 2017-12-05 Zihao Hu , Xiyi Luo , Hongtao Lu , Yong Yu

Large language models (LLMs) perform strongly on biological benchmarks, raising concerns that they may help novice actors acquire dual-use laboratory skills. Yet, whether this translates to improved human performance in the physical…

Large language models (LLMs) are having transformative impacts across a wide range of scientific fields, particularly in the biomedical sciences. Just as the goal of Natural Language Processing is to understand sequences of words, a major…

Genomics · Quantitative Biology 2024-09-24 Gonzalo Benegas , Chengzhong Ye , Carlos Albors , Jianan Canal Li , Yun S. Song

As the complexity of neural network models has grown, it has become increasingly important to optimize their design automatically through metalearning. Methods for discovering hyperparameters, topologies, and learning rate schedules have…

Machine Learning · Computer Science 2020-04-28 Santiago Gonzalez , Risto Miikkulainen

We investigate the effectiveness of fine-tuning large language models (LLMs) on small medical datasets for text classification and named entity recognition tasks. Using a German cardiology report dataset and the i2b2 Smoking Challenge…

Computation and Language · Computer Science 2025-03-28 Noah Losch , Lucas Plagwitz , Antonius Büscher , Julian Varghese

Protein language models (PLMs) have emerged as powerful tools to detect complex patterns of protein sequences. However, the capability of PLMs to fully capture information on protein sequences might be limited by focusing on single…

Machine Learning · Computer Science 2025-05-27 Hazem Alsamkary , Mohamed Elshaffei , Mohamed Elkerdawy , Ahmed Elnaggar

Many computer vision applications involve modeling complex spatio-temporal patterns in high-dimensional motion data. Recently, restricted Boltzmann machines (RBMs) have been widely used to capture and represent spatial patterns in a single…

Computer Vision and Pattern Recognition · Computer Science 2017-10-24 Siqi Nie , Ziheng Wang , Qiang Ji

Deterministic computer simulations are often used as a replacement for complex physical experiments. Although less expensive than physical experimentation, computer codes can still be time-consuming to run. An effective strategy for…

Methodology · Statistics 2010-03-04 Mark Franey , Pritam Ranjan , Hugh Chipman

State-of-the-art studies have demonstrated the superiority of joint modelling over pipeline implementation for medical named entity recognition and normalization due to the mutual benefits between the two processes. To exploit these…

Computation and Language · Computer Science 2018-12-17 Sendong Zhao , Ting Liu , Sicheng Zhao , Fei Wang

The explosive growth of large language models (LLMs) has created a vast but opaque landscape: millions of models exist, yet their evolutionary relationships through fine-tuning, distillation, or adaptation are often undocumented or unclear,…

Machine Learning · Computer Science 2026-05-04 Zhaomin Wu , Haodong Zhao , Ziyang Wang , Jizhou Guo , Qian Wang , Bingsheng He