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Aggregating multi-site brain MRI data can enhance deep learning model training, but also introduces non-biological heterogeneity caused by site-specific variations (e.g., differences in scanner vendors, acquisition parameters, and imaging…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Mengqi Wu , Yongheng Sun , Qianqian Wang , Pew-Thian Yap , Mingxia Liu

Reconstruction-based methods, particularly those leveraging autoencoders, have been widely adopted for anomaly detection task in brain MRI. Unlike most existing works try to improve the task accuracy through architectural or algorithmic…

Image and Video Processing · Electrical Eng. & Systems 2025-10-14 Zixuan Pan , Jun Xia , Zheyu Yan , Guoyue Xu , Yifan Qin , Xueyang Li , Yawen Wu , Zhenge Jia , Jianxu Chen , Yiyu Shi

Anomaly detection in medical imaging plays a crucial role in identifying pathological regions across various imaging modalities, such as brain MRI, liver CT, and carotid ultrasound (US). However, training fully supervised segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yuan Bi , Lucie Huang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab , Zhongliang Jiang

We introduce a novel state-space model (SSM)-based framework for skeleton-based human action recognition, with an anatomically-guided architecture that improves state-of-the-art performance in both clinical diagnostics and general action…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Niki Martinel , Mariano Serrao , Christian Micheloni

We introduce a method for manifold alignment of different modalities (or domains) of remote sensing images. The problem is recurrent when a set of multitemporal, multisource, multisensor and multiangular images is available. In these…

Computer Vision and Pattern Recognition · Computer Science 2021-04-19 Devis Tuia , Michele Volpi , Maxime Trolliet , Gustau Camps-Valls

Unsupervised anomaly detection stands as an important problem in machine learning, with applications in financial fraud prevention, network security and medical diagnostics. Existing unsupervised anomaly detection algorithms rarely perform…

Machine Learning · Computer Science 2026-02-04 Pritam Kar , Rahul Bordoloi , Olaf Wolkenhauer , Saptarshi Bej

Accurate 3D medical image segmentation requires a delicate balance between fine-grained local details and global contextual understanding. While spatial-domain models often struggle with long-range dependencies, existing frequency-based…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Bo Zhang , Yifan Zhang , Shuo Yan , Yu Bai , Zheng Zhang , Wu Liu , Wendong Wang , Yongdong Zhang

We develop a multiscale scanning method to find anomalies in a $d$-dimensional random field in the presence of nuisance parameters. This covers the common situation that either the baseline-level or additional parameters such as the…

Applications · Statistics 2024-09-20 Claudia König , Axel Munk , Frank Werner

Supervised deep learning techniques show promise in medical image analysis. However, they require comprehensive annotated data sets, which poses challenges, particularly for rare diseases. Consequently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Finn Behrendt , Debayan Bhattacharya , Lennart Maack , Julia Krüger , Roland Opfer , Robin Mieling , Alexander Schlaefer

In many real-world applications data exhibits non-stationarity, i.e., its distribution changes over time. One approach to handling non-stationarity is to remove or minimize it before attempting to analyze the data. In the context of brain…

Machine Learning · Computer Science 2016-05-26 Inbal Horev , Florian Yger , Masashi Sugiyama

Unsupervised anomaly detection methods offer a promising and flexible alternative to supervised approaches, holding the potential to revolutionize medical scan analysis and enhance diagnostic performance. In the current landscape, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Cosmin I. Bercea , Esther Puyol-Antón , Benedikt Wiestler , Daniel Rueckert , Julia A. Schnabel , Andrew P. King

Visual anomaly detection is common in several applications including medical screening and production quality check. Although a definition of the anomaly is an unknown trend in data, in many cases some hints or samples of the anomaly class…

Computer Vision and Pattern Recognition · Computer Science 2019-03-29 Daiki Kimura , Minori Narita , Asim Munawar , Ryuki Tachibana

Increasing the volume of training data can enable the auxiliary diagnostic algorithms for Autism Spectrum Disorder (ASD) to learn more accurate and stable models. However, due to the significant heterogeneity and domain shift in rs-fMRI…

Neurons and Cognition · Quantitative Biology 2025-07-11 Yiqian Luo , Qiurong Chen , Fali Li , Peng Xu , Yangsong Zhang

In medical imaging, obtaining large amounts of labeled data is often a hurdle, because annotations and pathologies are scarce. Anomaly detection is a method that is capable of detecting unseen abnormal data while only being trained on…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Djennifer K. Madzia-Madzou , Hugo J. Kuijf

Deep unsupervised anomaly detection in brain magnetic resonance imaging offers a promising route to identify pathological deviations without requiring lesion-specific annotations. Yet, fragmented evaluations, heterogeneous datasets, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Alexander Frotscher , Christian F. Baumgartner , Thomas Wolfers

Semi-Supervised classification and segmentation methods have been widely investigated in medical image analysis. Both approaches can improve the performance of fully-supervised methods with additional unlabeled data. However, as a…

Computer Vision and Pattern Recognition · Computer Science 2021-06-04 Hong-Yu Zhou , Chengdi Wang , Haofeng Li , Gang Wang , Shu Zhang , Weimin Li , Yizhou Yu

Despite the progress made in Mamba-based medical image segmentation models, existing methods utilizing unidirectional or multi-directional feature scanning mechanisms struggle to effectively capture dependencies between neighboring…

Image and Video Processing · Electrical Eng. & Systems 2025-09-04 Chao Fan , Hongyuan Yu , Yan Huang , Liang Wang , Zhenghan Yang , Xibin Jia

In the past three decades, neuroimaging has provided important insights into structure-function relationships in the human brain. Recently, however, the methods for analyzing functional magnetic resonance imaging (fMRI) data have come under…

Neurons and Cognition · Quantitative Biology 2022-01-21 Philipp Kellmeyer , Roland Berkemeier , Tonio Ball

Unsupervised anomaly detection is a challenging computer vision task, in which 2D-based anomaly detection methods have been extensively studied. However, multimodal anomaly detection based on RGB images and 3D point clouds requires further…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Zhongbin Sun , Xiaolong Li , Yiran Li , Yue Ma

Detecting anomalies in brain MRI scans using supervised deep learning methods presents challenges due to anatomical diversity and labor-intensive requirement of pixel-level annotations. Generative models like Denoising Diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Vivek Kumar Trivedi , Bheeshm Sharma , P. Balamurugan