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Knowledge graph completion (a.k.a.~link prediction), i.e.,~the task of inferring missing information from knowledge graphs, is a widely used task in many applications, such as product recommendation and question answering. The…

Artificial Intelligence · Computer Science 2022-07-05 Zoi Kaoudi , Abelardo Carlos Martinez Lorenzo , Volker Markl

Drug-drug interaction (DDI) prediction provides a drug combination strategy for systemically effective treatment. Previous studies usually model drug information constrained on a single view such as the drug itself, leading to incomplete…

Biomolecules · Quantitative Biology 2022-03-29 Zimeng Li , Shichao Zhu , Bin Shao , Tie-Yan Liu , Xiangxiang Zeng , Tong Wang

Disease prediction or classification using health datasets involve using well-known predictors associated with the disease as features for the models. This study considers multiple data components of an individual's health, using the…

Machine Learning · Computer Science 2016-08-18 Aileme Omogbai

Large pre-trained language models (LLMs) have been shown to have significant potential in few-shot learning across various fields, even with minimal training data. However, their ability to generalize to unseen tasks in more complex fields,…

Computation and Language · Computer Science 2023-04-24 Tianhao Li , Sandesh Shetty , Advaith Kamath , Ajay Jaiswal , Xianqian Jiang , Ying Ding , Yejin Kim

Relation-aware graph structure embedding is promising for predicting multi-relational drug-drug interactions (DDIs). Typically, most existing methods begin by constructing a multi-relational DDI graph and then learning relation-aware graph…

Machine Learning · Computer Science 2023-08-21 Mengying Jiang , Guizhong Liu , Biao Zhao , Yuanchao Su , Weiqiang Jin

The classification performance of the random vector functional link (RVFL), a randomized neural network, has been widely acknowledged. However, due to its shallow learning nature, RVFL often fails to consider all the relevant information…

Machine Learning · Computer Science 2025-02-11 M. Tanveer , R. K. Sharma , M. Sajid , A. Quadir

In the treatment of complex diseases, treatment regimens using a single drug often yield limited efficacy and can lead to drug resistance. In contrast, combination drug therapies can significantly improve therapeutic outcomes through…

Machine Learning · Computer Science 2026-04-24 Jiyan Song , Wenyang Wang , Chengcheng Yan , Zhiquan Han , Feifei Zhao

Feed-forward neural networks can be understood as a combination of an intermediate representation and a linear hypothesis. While most previous works aim to diversify the representations, we explore the complementary direction by performing…

Machine Learning · Computer Science 2019-10-24 Han Zhao , Yao-Hung Hubert Tsai , Ruslan Salakhutdinov , Geoffrey J. Gordon

Graphs can be used to effectively represent complex data structures. Learning these irregular data in graphs is challenging and still suffers from shallow learning. Applying deep learning on graphs has recently showed good performance in…

Machine Learning · Computer Science 2020-09-16 Thosini Bamunu Mudiyanselage , Xiujuan Lei , Nipuna Senanayake , Yanqing Zhang , Yi Pan

Link prediction is an open problem in the complex network, which attracts much research interest currently. However, little attention has been paid to the relation between network structure and the performance of prediction methods. In…

Social and Information Networks · Computer Science 2014-10-28 Xu Feng , Jichang Zhao , Ke Xu

Adverse drug reactions (ADRs) induced from high-order drug-drug interactions (DDIs) due to polypharmacy represent a significant public health problem. In this paper, we formally formulate the to-avoid and safe (with respect to ADRs) drug…

Information Retrieval · Computer Science 2018-03-09 Wen-Hao Chiang , Li Shen , Lang Li , Xia Ning

Retinal diseases can cause irreversible vision loss in both eyes if not diagnosed and treated early. Since retinal diseases are so complicated, retinal imaging is likely to show two or more abnormalities. Current deep learning techniques…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Tariq M Khan , Shahzaib Iqbal , Syed S. Naqvi , Imran Razzak , Erik Meijering

The widely used gene quantisation technique, Lateral Flow Device (LFD), is now commonly used to detect the presence of SARS-CoV-2. It is enabling the control and prevention of the spread of the virus. Depending on the viral load, LFD have…

Machine Learning · Computer Science 2022-05-27 Neeraj Vashistha

Diabetic retinopathy (DR) screening is instrumental in preventing blindness, but faces a scaling challenge as the number of diabetic patients rises. Risk stratification for the development of DR may help optimize screening intervals to…

In this mini-review, we explore the new prediction methods for drug combination synergy relying on high-throughput combinatorial screens. The fast progress of the field is witnessed in the more than thirty original machine learning methods…

Machine Learning · Computer Science 2024-04-16 Fatemeh Abbasi , Juho Rousu

Dereverberation of a moving speech source in the presence of other directional interferers, is a harder problem than that of stationary source and interference cancellation. We explore joint multi channel linear prediction (MCLP) and…

Audio and Speech Processing · Electrical Eng. & Systems 2019-10-23 Srikanth Raj Chetupalli , Thippur V. Sreenivas

Early identification of stroke is crucial for intervention, requiring reliable models. We proposed an efficient retinal image representation together with clinical information to capture a comprehensive overview of cardiovascular health,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-11 Yuqing Huang , Bastian Wittmann , Olga Demler , Bjoern Menze , Neda Davoudi

Computer-Aided Drug Discovery research has proven to be a promising direction in drug discovery. In recent years, Deep Learning approaches have been applied to problems in the domain such as Drug-Target Interaction Prediction and have shown…

Machine Learning · Computer Science 2020-04-28 Brighter Agyemang , Wei-Ping Wu , Michael Y. Kpiebaareh , Ebenezer Nanor

Unmeasured spatial confounding complicates exposure effect estimation in environmental health studies. This problem is exacerbated in studies with multiple health outcomes and environmental exposure variables, as the source and magnitude of…

Surgical tool presence detection and surgical phase recognition are two fundamental yet challenging tasks in surgical video analysis and also very essential components in various applications in modern operating rooms. While these two…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Yueming Jin , Huaxia Li , Qi Dou , Hao Chen , Jing Qin , Chi-Wing Fu , Pheng-Ann Heng