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It is increasingly common to encounter data from dynamic processes captured by static cross-sectional measurements over time, particularly in biomedical settings. Recent attempts to model individual trajectories from this data use optimal…

Machine Learning · Statistics 2020-07-28 Alexander Tong , Jessie Huang , Guy Wolf , David van Dijk , Smita Krishnaswamy

Recent years have witnessed an increased focus on interpretability and the use of machine learning to inform policy analysis and decision making. This paper applies machine learning to examine travel behavior and, in particular, on modeling…

Machine Learning · Computer Science 2019-02-11 Xilei Zhao , Xiang Yan , Pascal Van Hentenryck

The rapid development of the mobile Internet and the Internet of Things is leading to a diversification of user devices and the emergence of new mobile applications on a regular basis. Such applications include those that are…

Computational Engineering, Finance, and Science · Computer Science 2024-08-13 Xirui Tang , Zeyu Wang , Xiaowei Cai , Honghua Su , Changsong Wei

Neural population activity relating to behaviour is assumed to be inherently low-dimensional despite the observed high dimensionality of data recorded using multi-electrode arrays. Therefore, predicting behaviour from neural population…

Neurons and Cognition · Quantitative Biology 2022-02-17 Justin Jude , Matthew G Perich , Lee E Miller , Matthias H Hennig

We introduce a novel gene regulatory network (GRN) inference method that integrates optimal transport (OT) with a deep-learning structural inference model. Advances in next-generation sequencing enable detailed yet destructive gene…

Computational Engineering, Finance, and Science · Computer Science 2024-09-24 Tsz Pan Tong , Aoran Wang , George Panagopoulos , Jun Pang

To support the modern machine-type communications, a crucial task during the random access phase is device activity detection, which is to detect the active devices from a large number of potential devices based on the received signal at…

Information Theory · Computer Science 2021-12-21 Yang Li , Zhilin Chen , Yunqi Wang , Chenyang Yang , Yik-Chung Wu

We consider the problem of optimizing the interconnection graphs of complex networks to promote synchronization. When traditional optimization methods are inapplicable, due to uncertain or unknown node dynamics, we propose a data-driven…

Systems and Control · Electrical Eng. & Systems 2023-09-29 Marco Coraggio , Mario di Bernardo

To remedy the drawbacks of full-mass or fixed-mass constraints in classical optimal transport, we propose adaptive optimal transport which is distinctive from the classical optimal transport in its ability of adaptive-mass preserving. It…

Machine Learning · Computer Science 2025-03-10 Pei Yang , Qi Tan , Guihua Wen

Integrative learning of multiple datasets has the potential to mitigate the challenge of small $n$ and large $p$ that is often encountered in analysis of big biomedical data such as genomics data. Detection of weak yet important signals can…

Methodology · Statistics 2022-07-04 Changgee Chang , Zongyu Dai , Jihwan Oh , Qi Long

Physical activity is crucial for human health. With the increasing availability of large-scale mobile health data, strong associations have been found between physical activity and various diseases. However, accurately capturing this…

Applications · Statistics 2025-01-03 Xiaojing Sun , Bingxin Zhao , Fei Xue

Adaptive experiments automatically optimize their design throughout the data collection process, which can bring substantial benefits compared to conventional experimental settings. Potential applications include, among others: computerized…

Methodology · Statistics 2026-04-01 Lucas Gautheron , Nori Jacoby , Peter Harrison

Predicting the bioactivity of a ligand is one of the hardest and most important challenges in computer-aided drug discovery. Despite years of data collection and curation efforts by research organizations worldwide, bioactivity data remains…

Quantitative Methods · Quantitative Biology 2023-08-21 Lucian Chan , Marcel Verdonk , Carl Poelking

Modern neural interfaces allow access to the activity of up to a million neurons within brain circuits. However, bandwidth limits often create a trade-off between greater spatial sampling (more channels or pixels) and the temporal frequency…

Learning the continuous dynamics of a system from snapshots of its temporal marginals is a problem which appears throughout natural sciences and machine learning, including in quantum systems, single-cell biological data, and generative…

Machine Learning · Computer Science 2023-06-12 Kirill Neklyudov , Rob Brekelmans , Daniel Severo , Alireza Makhzani

Interactive multi-agent simulation algorithms are used to compute the trajectories and behaviors of different entities in virtual reality scenarios. However, current methods involve considerable parameter tweaking to generate plausible…

Graphics · Computer Science 2018-12-04 Jiaping Ren , Wei Xiang , Yangxi Xiao , Ruigang Yang , Dinesh Manocha , Xiaogang Jin

Hypergraph can capture complex and higher-order dependencies among learners and learning resources in personalized educational recommender systems. Many existing hypergraph-based recommendation approaches underexplored the dynamic…

Information Retrieval · Computer Science 2026-03-17 Tao Xie , Yan Li , Yongpan Sheng , Jian Liao

The network inference problem arises in biological research when one needs to quantitatively choose the best protein-interaction model for explaining a phenotype. The diverse nature of the data and nonlinear dynamics pose significant…

Molecular Networks · Quantitative Biology 2025-12-22 Guy Karlebach

Unsupervised learning aims at the discovery of hidden structure that drives the observations in the real world. It is essential for success in modern machine learning. Latent variable models are versatile in unsupervised learning and have…

Machine Learning · Computer Science 2016-06-13 Furong Huang

Optimal transport is a framework that facilitates the most efficient allocation of a limited amount of resources. However, the most efficient allocation scheme does not necessarily preserve the most fairness. In this paper, we establish a…

Optimization and Control · Mathematics 2021-04-01 Jason Hughes , Juntao Chen

The links between optimal control of dynamical systems and neural networks have proved beneficial both from a theoretical and from a practical point of view. Several researchers have exploited these links to investigate the stability of…

Optimization and Control · Mathematics 2019-02-08 Panos Parpas , Corey Muir