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Protein-ligand binding affinity is critical in drug discovery, but experimentally determining it is time-consuming and expensive. Artificial intelligence (AI) has been used to predict binding affinity, significantly accelerating this…

Emerging Technologies · Computer Science 2025-09-16 Seon-Geun Jeong , Kyeong-Hwan Moon , Won-Joo Hwang

Traditional deep learning models implicity encode knowledge limiting their transparency and ability to adapt to data changes. Yet, this adaptability is vital for addressing user data privacy concerns. We address this limitation by storing…

Computer Vision and Pattern Recognition · Computer Science 2024-02-21 Sebastian Doerrich , Tobias Archut , Francesco Di Salvo , Christian Ledig

Indices for approximate nearest neighbor search (ANNS) are a basic component for information retrieval and widely used in database, search, recommendation and RAG systems. In these scenarios, documents or other objects are inserted into and…

Information Retrieval · Computer Science 2025-02-20 Haike Xu , Magdalen Dobson Manohar , Philip A. Bernstein , Badrish Chandramouli , Richard Wen , Harsha Vardhan Simhadri

Approximate nearest neighbor (ANN) search is a fundamental problem in areas such as data management,information retrieval and machine learning. Recently, Li et al. proposed a learned approach named AdaptNN to support adaptive ANN query…

Databases · Computer Science 2021-10-05 Kaixiang Yang , Hongya Wang , Bo Xu , Wei Wang , Yingyuan Xiao , Ming Du , Junfeng Zhou

Reverse k nearest neighbor (RkNN) queries are fundamental in spatial databases, location-based analytics, and recommendation systems. Existing state-of-the-art techniques rely on spatial pruning supported by R-trees and their variants.…

Databases · Computer Science 2026-05-27 Zhengyang Bai , Peng Chen , Mohamed Wahib

In an ever expanding set of research and application areas, deep neural networks (DNNs) set the bar for algorithm performance. However, depending upon additional constraints such as processing power and execution time limits, or…

Machine Learning · Computer Science 2021-06-22 Nathan Dahlin , Krishna Chaitanya Kalagarla , Nikhil Naik , Rahul Jain , Pierluigi Nuzzo

In real-world applications, anomaly detection (AD) often operates without access to anomalous data, necessitating semi-supervised methods that rely solely on normal data. Among these methods, deep k-nearest neighbor (deep kNN) AD stands out…

The effectiveness of existing denoising algorithms typically relies on accurate pre-defined noise statistics or plenty of paired data, which limits their practicality. In this work, we focus on denoising in the more common case where noise…

Image and Video Processing · Electrical Eng. & Systems 2020-12-01 Huangxing Lin , Yihong Zhuang , Yue Huang , Xinghao Ding , Yizhou Yu , Xiaoqing Liu , John Paisley

Deep neural networks (DNNs) have become the driving force behind recent artificial intelligence (AI) research. An important problem with implementing a neural network is the design of its architecture. Typically, such an architecture is…

Neural and Evolutionary Computing · Computer Science 2021-03-30 Shayan Hassantabar , Zeyu Wang , Niraj K. Jha

Approximate nearest neighbor search (ANNS) has become vital to modern AI infrastructure, particularly in retrieval-augmented generation (RAG) applications. Numerous in-browser ANNS engines have emerged to seamlessly integrate with popular…

Information Retrieval · Computer Science 2025-07-03 Mugeng Liu , Siqi Zhong , Qi Yang , Yudong Han , Xuanzhe Liu , Yun Ma

Approximate nearest neighbor (ANN) search in high-dimensional Euclidean space has a broad range of applications. Among existing ANN algorithms, graph-based methods have shown superior performance in terms of the time-accuracy trade-off.…

Databases · Computer Science 2024-11-20 Yutong Gou , Jianyang Gao , Yuexuan Xu , Cheng Long

Efficient Nearest Neighbor (NN) search in high-dimensional spaces is a foundation of many multimedia retrieval systems. Because it offers low responses times, Product Quantization (PQ) is a popular solution. PQ compresses high-dimensional…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Fabien André , Anne-Marie Kermarrec , Nicolas Le Scouarnec

The k-nearest neighbors (kNN) algorithm is a cornerstone of non-parametric classification in artificial intelligence, yet its deployment in large-scale applications is persistently constrained by the computational trade-off between…

Machine Learning · Computer Science 2026-01-26 Jiaye Li , Gang Chen , Hang Xu , Shichao Zhang

Nowadays, face recognition and more generally image recognition have many applications in the modern world and are widely used in our daily tasks. This paper aims to propose a distributed approximate nearest neighbor (ANN) method for…

Computer Vision and Pattern Recognition · Computer Science 2020-08-31 Aysan Aghazadeh , Maryam Amirmazlaghani

Filtered Approximate Nearest Neighbor (ANN) search retrieves the closest vectors for a query vector from a dataset. It enforces that a specified set of discrete labels $S$ for the query must be included in the labels of each retrieved…

Machine Learning · Computer Science 2025-11-07 Ananya Sutradhar , Suryansh Gupta , Ravishankar Krishnaswamy , Haiyang Xu , Aseem Rastogi , Gopal Srinivasa

Neural network classifiers have become the de-facto choice for current "pre-train then fine-tune" paradigms of visual classification. In this paper, we investigate k-Nearest-Neighbor (k-NN) classifiers, a classical model-free learning…

Computer Vision and Pattern Recognition · Computer Science 2021-12-21 Menglin Jia , Bor-Chun Chen , Zuxuan Wu , Claire Cardie , Serge Belongie , Ser-Nam Lim

Existing methods for retrieving k-nearest neighbours suffer from the curse of dimensionality. We argue this is caused in part by inherent deficiencies of space partitioning, which is the underlying strategy used by most existing methods. We…

Data Structures and Algorithms · Computer Science 2017-04-07 Ke Li , Jitendra Malik

Replacing non-polynomial functions (e.g., non-linear activation functions such as ReLU) in a neural network with their polynomial approximations is a standard practice in privacy-preserving machine learning. The resulting neural network,…

Machine Learning · Computer Science 2024-06-10 Chi Zhang , Jingjing Fan , Man Ho Au , Siu Ming Yiu

Approximate Nearest Neighbor Search (ANNS) is a critical component of modern AI systems, such as recommendation engines and retrieval-augmented large language models (RAG-LLMs). However, scaling ANNS to billion-entry datasets exposes…

Hardware Architecture · Computer Science 2025-08-21 Sitian Chen , Amelie Chi Zhou , Yucheng Shi , Yusen Li , Xin Yao

The unprecedented performance of deep neural networks (DNNs) has led to large strides in various Artificial Intelligence (AI) inference tasks, such as object and speech recognition. Nevertheless, deploying such AI models across commodity…

Machine Learning · Computer Science 2021-06-30 Stylianos I. Venieris , Ioannis Panopoulos , Ilias Leontiadis , Iakovos S. Venieris
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