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Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

Recent advances in Large Language Models (LLMs) have enabled them to overcome their context window limitations, and demonstrate exceptional retrieval and reasoning capacities on longer context. Quesion-answering systems augmented with…

Computation and Language · Computer Science 2024-11-19 Zixiong Wang , Gaoyang Liu , Yang Yang , Chen Wang

Large Language Models (LLMs) have enabled a wide range of applications through their powerful capabilities in language understanding and generation. However, as LLMs are trained on static corpora, they face difficulties in addressing…

Computation and Language · Computer Science 2025-10-13 Yongjie Wang , Yue Yu , Kaisong Song , Jun Lin , Zhiqi Shen

Membership inference attack (MIA) has become one of the most widely used and effective methods for evaluating the privacy risks of machine learning models. These attacks aim to determine whether a specific sample is part of the model's…

Cryptography and Security · Computer Science 2025-06-04 Jing Xue , Zhishen Sun , Haishan Ye , Luo Luo , Xiangyu Chang , Ivor Tsang , Guang Dai

The deployment of large language models (LLMs) like ChatGPT and Gemini has shown their powerful natural language generation capabilities. However, these models can inadvertently learn and retain sensitive information and harmful content…

Cryptography and Security · Computer Science 2025-10-14 Shang Wang , Tianqing Zhu , Dayong Ye , Wanlei Zhou

Retrieval-Augmented Generation (RAG) enhances large language models (LLMs) by retrieving relevant documents from external sources to improve factual accuracy and verifiability. However, this reliance introduces new attack surfaces within…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Saket S. Chaturvedi , Gaurav Bagwe , Lan Zhang , Xiaoyong Yuan

Large Language Models (LLMs) are increasingly integrating memory functionalities to provide personalized and context-aware interactions. However, user understanding, practices and expectations regarding these memory systems are not yet well…

Human-Computer Interaction · Computer Science 2025-08-12 Shuning Zhang , Rongjun Ma , Ying Ma , Shixuan Li , Yiqun Xu , Xin Yi , Hewu Li

Large Language Models (LLMs) are increasingly deployed to enable or improve a multitude of real-world applications. Given the large size of their training data sets, their tendency to memorize training data raises serious privacy and…

Machine Learning · Computer Science 2026-01-27 Pedram Zaree , Md Abdullah Al Mamun , Yue Dong , Ihsen Alouani , Nael Abu-Ghazaleh

Retrieval augmented generation (RAG) is frequently used to mitigate hallucinations and provide up-to-date knowledge for large language models (LLMs). However, given that document retrieval is an imprecise task and sometimes results in…

Computation and Language · Computer Science 2025-02-10 Kevin Wu , Eric Wu , James Zou

Recent advances in large language models (LLMs) have led to impressive progress in natural language generation, yet their tendency to produce hallucinated or unsubstantiated content remains a critical concern. To improve factual…

Computation and Language · Computer Science 2025-05-20 Xukai Liu , Ye Liu , Shiwen Wu , Yanghai Zhang , Yihao Yuan , Kai Zhang , Qi Liu

Retrieval-Augmented Generation (RAG) has gained significant attention in recent years for its potential to enhance natural language understanding and generation by combining large-scale retrieval systems with generative models. RAG…

Computation and Language · Computer Science 2025-03-18 Mingyue Cheng , Yucong Luo , Jie Ouyang , Qi Liu , Huijie Liu , Li Li , Shuo Yu , Bohou Zhang , Jiawei Cao , Jie Ma , Daoyu Wang , Enhong Chen

Membership Inference Attacks (MIAs) pose a critical privacy threat by enabling adversaries to determine whether a specific sample was included in a model's training dataset. Despite extensive research on MIAs, systematic comparisons between…

Cryptography and Security · Computer Science 2025-10-21 Owais Makroo , Siva Rajesh Kasa , Sumegh Roychowdhury , Karan Gupta , Nikhil Pattisapu , Santhosh Kasa , Sumit Negi

Retrieval-Augmented Generation (RAG) systems offer a powerful approach to enhancing large language model (LLM) outputs by incorporating fact-checked, contextually relevant information. However, fairness and reliability concerns persist, as…

Human-Computer Interaction · Computer Science 2025-04-24 Xuyang Zhu , Sejoon Chang , Andrew Kuik

Recent advances in large language models (LLMs) have made a profound impact on our society and also raised new security concerns. Particularly, due to the remarkable inference ability of LLMs, the privacy violation attack (PVA), revealed by…

Cryptography and Security · Computer Science 2025-06-26 Wanli Peng , Xin Chen , Hang Fu , XinYu He , Xue Yiming , Juan Wen

Machine learning models are known to leak sensitive information, as they inevitably memorize (parts of) their training data. More alarmingly, large language models (LLMs) are now trained on nearly all available data, which amplifies the…

Machine Learning · Computer Science 2025-10-10 Jiashu Tao , Reza Shokri

The lack of domain-specific data in the pre-training of Large Language Models (LLMs) severely limits LLM-based decision systems in specialized applications, while post-training a model in the scenarios requires significant computational…

Artificial Intelligence · Computer Science 2025-05-05 Zongyuan Li , Pengfei Li , Runnan Qi , Yanan Ni , Lumin Jiang , Hui Wu , Xuebo Zhang , Kuihua Huang , Xian Guo

Retrieval-Augmented Generation (RAG) is a technique that enhances the capabilities of large language models (LLMs) by incorporating external knowledge sources. This method addresses common LLM limitations, including outdated information and…

Computation and Language · Computer Science 2024-07-16 Yuanjie Lyu , Zhiyu Li , Simin Niu , Feiyu Xiong , Bo Tang , Wenjin Wang , Hao Wu , Huanyong Liu , Tong Xu , Enhong Chen

Membership inference attacks (MIAs) infer whether a specific data record is used for target model training. MIAs have provoked many discussions in the information security community since they give rise to severe data privacy issues,…

Artificial Intelligence · Computer Science 2022-03-02 Yu Wang , Lifu Huang , Philip S. Yu , Lichao Sun

Retrieval-Augmented Generation (RAG) has gained significant popularity in modern Large Language Models (LLMs) due to its effectiveness in introducing new knowledge and reducing hallucinations. However, the deep understanding of RAG remains…

Computation and Language · Computer Science 2024-10-07 Jingyu Liu , Jiaen Lin , Yong Liu

Retrieval-Augmented Generation (RAG) is a promising approach to mitigate hallucinations in Large Language Models (LLMs) for legal applications, but its reliability is critically dependent on the accuracy of the retrieval step. This is…

Computation and Language · Computer Science 2025-10-09 Markus Reuter , Tobias Lingenberg , Rūta Liepiņa , Francesca Lagioia , Marco Lippi , Giovanni Sartor , Andrea Passerini , Burcu Sayin