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Sampling from discrete distributions with multiple modes and energy barriers is fundamental to machine learning and computational physics. Recent discrete neural samplers like MDNS suffer from mode collapse and fail to sample high-energy…

Mass spectrometry (MS) is essential for proteomics and metabolomics but faces impending challenges in efficiently processing the vast volumes of data. This paper introduces SpecPCM, an in-memory computing (IMC) accelerator designed to…

Hardware Architecture · Computer Science 2024-11-18 Keming Fan , Ashkan Moradifirouzabadi , Xiangjin Wu , Zheyu Li , Flavio Ponzina , Anton Persson , Eric Pop , Tajana Rosing , Mingu Kang

Motivation: Despite significant advances in Third-Generation Sequencing (TGS) technologies, Next-Generation Sequencing (NGS) technologies remain dominant in the current sequencing market. This is due to the lower error rates and richer…

Information Theory · Computer Science 2023-04-04 Jia Wang , Yi Niu , Tianyi Xu , Mingming Ma , Dahua Gao , Guangming Shi

In the past few years, we have envisioned an increasing number of businesses start driving by big data analytics, such as Amazon recommendations and Google Advertisements. At the back-end side, the businesses are powered by big data…

Performance · Computer Science 2021-10-26 Ying Mao , Victoria Green , Jiayin Wang , Haoyi Xiong , Zhishan Guo

Workflow scheduling is a long-studied problem in parallel and distributed computing (PDC), aiming to efficiently utilize compute resources to meet user's service requirements. Recently proposed scheduling methods leverage the low response…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-12-15 Shreshth Tuli , Giuliano Casale , Nicholas R. Jennings

With the rapid growth of global e-commerce, the demand for automation in the logistics industry is increasing. This study focuses on automated picking systems in warehouses, utilizing deep learning and reinforcement learning technologies to…

Robotics · Computer Science 2026-02-10 Keqin Li , Jin Wang , Xubo Wu , Xirui Peng , Runmian Chang , Xiaoyu Deng , Yiwen Kang , Yue Yang , Fanghao Ni , Bo Hong

The ability to quickly and accurately identify microbial species in a sample, known as metagenomic profiling, is critical across various fields, from healthcare to environmental science. This paper introduces a novel method to profile…

Genomics · Quantitative Biology 2025-04-10 Riselda Kodra , Hadjer Benmeziane , Irem Boybat , William Andrew Simon

Mobile edge generation (MEG) is an emerging technology that allows the network to meet the challenging traffic load expectations posed by the rise of generative artificial intelligence~(GAI). A novel MEG model is proposed for deploying GAI…

Information Theory · Computer Science 2024-09-11 Ruikang Zhong , Xidong Mu , Mona Jaber , Yuanwei Liu

Coreset selection is powerful in reducing computational costs and accelerating data processing for deep learning algorithms. It strives to identify a small subset from large-scale data, so that training only on the subset practically…

Machine Learning · Computer Science 2024-03-01 Xiaobo Xia , Jiale Liu , Shaokun Zhang , Qingyun Wu , Hongxin Wei , Tongliang Liu

MEMS storage devices are new non-volatile secondary storages that have outstanding advantages over magnetic disks. MEMS storage devices, however, are much different from magnetic disks in the structure and access characteristics. They have…

Databases · Computer Science 2015-05-13 Yi-Reun Kim , Kyu-Young Whang , Min-Soo Kim , Il-Yeol Song

Bone metastasis analysis is a significant challenge in pathology and plays a critical role in determining patient quality of life and treatment strategies. The microenvironment and specific tissue structures are essential for pathologists…

Computer Vision and Pattern Recognition · Computer Science 2025-01-29 Yuxuan Chen , Jiawen Li , Huijuan Shi , Yang Xu , Tian Guan , Lianghui Zhu , Yonghong He , Anjia Han

A wide variety of large-scale data has been produced in bioinformatics. In response, the need for efficient handling of biomedical big data has been partly met by parallel computing. However, the time demand of many bioinformatics programs…

Genomics · Quantitative Biology 2015-08-11 Sungmin Lee , Hyeyoung Min , Sungroh Yoon

Persistent partitioning is effective in avoiding expensive shuffling operations. However it remains a significant challenge to automate this process for Big Data analytics workloads that extensively use user defined functions (UDFs), where…

Databases · Computer Science 2021-02-23 Jia Zou , Amitabh Das , Pratik Barhate , Arun Iyengar , Binhang Yuan , Dimitrije Jankov , Chris Jermaine

Emerging edge applications require both a fast response latency and complex processing. This is infeasible without expensive hardware that can process complex operations -- such as object detection -- within a short time. Many approach this…

Systems and Control · Electrical Eng. & Systems 2022-01-04 Samaa Gazzaz , Vishal Chakraborty , Faisal Nawab

Large Language Models (LLMs) have become an essential infrastructure for Artificial General Intelligence (AGI), yet their lack of well-defined memory management systems hinders the development of long-context reasoning, continual…

Fast surrogate modeling for high-dimensional physical dynamics requires more than low short-term error: useful models must roll out efficiently while preserving the statistical structure of long trajectories. Neural operators provide…

Machine Learning · Computer Science 2026-05-08 Tianyue Yang , Xiao Xue

Industrial domains such as automotive, robotics, and aerospace are rapidly evolving to satisfy the increasing demand for machine-learning-driven Autonomy, Connectivity, Electrification, and Shared mobility (ACES). This paradigm shift…

Hardware Architecture · Computer Science 2026-02-11 Thomas Benz

The advancements in data acquisition, storage, and processing techniques have resulted in the rapid growth of heterogeneous medical data. Integrating radiological scans, histopathology images, and molecular information with clinical data is…

Machine Learning · Computer Science 2023-12-25 Aakash Tripathi , Asim Waqas , Kavya Venkatesan , Yasin Yilmaz , Ghulam Rasool

The tremendous potential exhibited by deep learning is often offset by architectural and computational complexity, making widespread deployment a challenge for edge scenarios such as mobile and other consumer devices. To tackle this…

Neural and Evolutionary Computing · Computer Science 2018-11-15 Alexander Wong , Mohammad Javad Shafiee , Brendan Chwyl , Francis Li

Meta computing is a new computing paradigm that aims to efficiently utilize all network computing resources to provide fault-tolerant, personalized services with strong security and privacy guarantees. It also seeks to virtualize the…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-21 Mengjie Liu , Yihua Li , Fangyi Mou , Zhiqing Tang , Jiong Lou , Jianxiong Guo , Weijia Jia