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Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

Intrinsic self-correct was a method that instructed large language models (LLMs) to verify and correct their responses without external feedback. Unfortunately, the study concluded that the LLMs could not self-correct reasoning yet. We find…

Computation and Language · Computer Science 2024-10-04 Zhenyu Wu , Qingkai Zeng , Zhihan Zhang , Zhaoxuan Tan , Chao Shen , Meng Jiang

We propose a human in the loop approach for black-box testing of Functional Mock-up Units (FMUs) using Large Language Models (LLMs). The goal is to reduce the manual effort in defining test scenarios for dynamic simulation models and to…

Software Engineering · Computer Science 2026-04-29 Abdullah Mughees , Gaadha Sudheerbabu , Tanwir Ahmad , Dragos Truscan , Mikael Manngård , Kristian Klemets

Large Language Models (LLMs) have shown remarkable capabilities in natural language processing but exhibit significant performance gaps among different languages. Most existing approaches to address these disparities rely on pretraining or…

Computation and Language · Computer Science 2024-10-17 Weixuan Wang , Minghao Wu , Barry Haddow , Alexandra Birch

In-context learning (ICL) facilitates Large Language Models (LLMs) exhibiting emergent ability on downstream tasks without updating billions of parameters. However, in the area of multi-modal Large Language Models (MLLMs), two problems…

Multimedia · Computer Science 2024-07-02 Jun Gao , Qian Qiao , Ziqiang Cao , Zili Wang , Wenjie Li

Accurate prediction of treatment outcomes in lung cancer remains challenging due to the sparsity, heterogeneity, and contextual overload of real-world electronic health data. Traditional models often fail to capture semantic information…

Black-box Large Language Models (LLMs) provide practical and accessible alternatives to other machine learning methods, as they require minimal labeled data and machine learning expertise to develop solutions for various decision making…

Machine Learning · Computer Science 2025-10-22 Ege Beyazit , KL Navaneet , Prashant Mathur , Roi Blanco , Vidit Bansal , Karim Bouyarmane

Large language models (LLMs) are increasingly used as automated judges to evaluate recommendation systems, search engines, and other subjective tasks, where relying on human evaluators can be costly, time-consuming, and unscalable. LLMs…

Computation and Language · Computer Science 2025-02-10 Gerrit J. J. van den Burg , Gen Suzuki , Wei Liu , Murat Sensoy

Automation is one of the cornerstones of contemporary material discovery. Bayesian optimization (BO) is an essential part of such workflows, enabling scientists to leverage prior domain knowledge into efficient exploration of a large…

Machine Learning · Computer Science 2024-05-30 Agustinus Kristiadi , Felix Strieth-Kalthoff , Marta Skreta , Pascal Poupart , Alán Aspuru-Guzik , Geoff Pleiss

Pre-trained vision-language models like CLIP have remarkably adapted to various downstream tasks. Nonetheless, their performance heavily depends on the specificity of the input text prompts, which requires skillful prompt template…

Machine Learning · Computer Science 2024-10-22 Yingjun Du , Wenfang Sun , Cees G. M. Snoek

The recent development of Large Language Models (LLMs) has been accompanied by an effervescence of novel ideas and methods to better optimize the loss of deep learning models. Claims from those methods are myriad: from faster convergence to…

Machine Learning · Computer Science 2025-09-03 Andrei Semenov , Matteo Pagliardini , Martin Jaggi

We present Lil-Bevo, our submission to the BabyLM Challenge. We pretrained our masked language models with three ingredients: an initial pretraining with music data, training on shorter sequences before training on longer ones, and masking…

Computation and Language · Computer Science 2026-04-17 Venkata S Govindarajan , Juan Diego Rodriguez , Kaj Bostrom , Kyle Mahowald

Large language models (LLMs) exhibit remarkable capabilities across diverse tasks, yet aligning them efficiently and effectively with human expectations remains a critical challenge. This thesis advances LLM alignment by introducing novel…

Computation and Language · Computer Science 2025-06-12 Yuxin Jiang

The personalization of black-box large language models (LLMs) is a critical yet challenging task. Existing approaches predominantly rely on context injection, where user history is embedded into the prompt to directly guide the generation…

Computation and Language · Computer Science 2025-11-10 Teqi Hao , Xioayu Tan , Shaojie Shi , Yinghui Xu , Xihe Qiu

Formulating mathematical models from real-world decision problems is a core task in Operational Research, yet it typically requires considerable human expertise and effort, limiting practical application. Recent advances in large language…

Optimization and Control · Mathematics 2025-11-05 Qingyang Li , Lele Zhang , Vicky Mak-Hau

In this paper, we present NEMO, a system that translates Natural-language descriptions of decision problems into formal Executable Mathematical Optimization implementations, operating collaboratively with users or autonomously. Existing…

Artificial Intelligence · Computer Science 2026-01-30 Yang Song , Anoushka Vyas , Zirui Wei , Sina Khoshfetrat Pakazad , Henrik Ohlsson , Graham Neubig

When we manually design an evolutionary optimization algorithm, we implicitly or explicitly assume a set of target optimization problems. In the case of automated algorithm design, target optimization problems are usually explicitly shown.…

Neural and Evolutionary Computing · Computer Science 2025-03-03 Lie Meng Pang , Hisao Ishibuchi

Although LLM-based agents have attracted significant attention in domains such as software engineering and machine learning research, their role in advancing combinatorial optimization (CO) remains relatively underexplored. This gap…

Computation and Language · Computer Science 2025-08-25 Weiwei Sun , Shengyu Feng , Shanda Li , Yiming Yang

Large language models (LLM) have become a critical component in many applications of machine learning. However, standard approaches to training LLM require a large number of tightly interconnected accelerators, with devices exchanging…

Today's large language models (LLMs) typically train on short text segments (e.g., <4K tokens) due to the quadratic complexity of their Transformer architectures. As a result, their performance suffers drastically on inputs longer than…

Computation and Language · Computer Science 2024-06-26 Chi Han , Qifan Wang , Hao Peng , Wenhan Xiong , Yu Chen , Heng Ji , Sinong Wang