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Alzheimer's disease (AD) is a progressive neurodegenerative disease most often associated with memory deficits and cognitive decline. With the aging population, there has been much interest in automated methods for cognitive impairment…

Audio and Speech Processing · Electrical Eng. & Systems 2023-03-07 Bastiaan Tamm , Rik Vandenberghe , Hugo Van hamme

Dysarthria, a condition resulting from impaired control of the speech muscles due to neurological disorders, significantly impacts the communication and quality of life of patients. The condition's complexity, human scoring and varied…

Neurons and Cognition · Quantitative Biology 2024-03-05 Lauren Stumpf , Balasundaram Kadirvelu , Sigourney Waibel , A. Aldo Faisal

Spoken Language Understanding (SLU) systems parse speech into semantic structures like dialog acts and slots. This involves the use of an Automatic Speech Recognizer (ASR) to transcribe speech into multiple text alternatives (hypotheses).…

Computation and Language · Computer Science 2021-06-14 Karthik Ganesan , Pakhi Bamdev , Jaivarsan B , Amresh Venugopal , Abhinav Tushar

Alzheimer's disease is a progressive, neurodegenerative disorder that causes memory loss and cognitive decline. While there has been extensive research in applying deep learning models to Alzheimer's prediction tasks, these models remain…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Emily Kaczmarek , Justin Szeto , Brennan Nichyporuk , Tal Arbel

Early detection is crucial to prevent the progression of Alzheimer's disease (AD). Thus, specialists can begin preventive treatment as soon as possible. They demand fast and precise assessment in the diagnosis of AD in the earliest and…

Machine Learning · Computer Science 2021-05-19 Alejandro Puente-Castro , Enrique Fernandez-Blanco , Alejandro Pazos , Cristian R. Munteanu

Early diagnosis of Alzheimer's disease (AD) is crucial in facilitating preventive care and to delay further progression. Speech based automatic AD screening systems provide a non-intrusive and more scalable alternative to other clinical…

Computation and Language · Computer Science 2023-04-03 Yi Wang , Jiajun Deng , Tianzi Wang , Bo Zheng , Shoukang Hu , Xunying Liu , Helen Meng

Amyotrophic Lateral Sclerosis (ALS) is a rare neurodegenerative disease, and high-quality EEG data from ALS patients are scarce. This data scarcity, coupled with severe class imbalance between ALS and healthy control recordings, poses a…

Machine Learning · Computer Science 2025-06-23 Abdulvahap Mutlu , Şengül Doğan , Türker Tuncer

Hypernasality is an abnormal resonance in human speech production, especially in patients with craniofacial anomalies such as cleft palate. In clinical application, hypernasality estimation is crucial in cleft palate diagnosis, as its…

Audio and Speech Processing · Electrical Eng. & Systems 2022-08-11 Kaitao Song , Teng Wan , Bixia Wang , Huiqiang Jiang , Luna Qiu , Jiahang Xu , Liping Jiang , Qun Lou , Yuqing Yang , Dongsheng Li , Xudong Wang , Lili Qiu

Diagnosing autism spectrum disorder (ASD) by identifying abnormal speech patterns from examiner-patient dialogues presents significant challenges due to the subtle and diverse manifestations of speech-related symptoms in affected…

Sound · Computer Science 2024-05-09 Chuanbo Hu , Jacob Thrasher , Wenqi Li , Mindi Ruan , Xiangxu Yu , Lynn K Paul , Shuo Wang , Xin Li

Recent advances in sequence modeling have highlighted the strengths of the transformer architecture, especially in achieving state-of-the-art machine translation results. However, depending on the up-stream systems, e.g., speech…

Computation and Language · Computer Science 2019-06-14 Pei Zhang , Boxing Chen , Niyu Ge , Kai Fan

Recognizing overlapping speech from multiple speakers in conversational scenarios is one of the most challenging problem for automatic speech recognition (ASR). Serialized output training (SOT) is a classic method to address multi-talker…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-02 Mohan Shi , Zengrui Jin , Yaoxun Xu , Yong Xu , Shi-Xiong Zhang , Kun Wei , Yiwen Shao , Chunlei Zhang , Dong Yu

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to irreversible cognitive decline in memory and communication. Early detection of AD through speech analysis is crucial for delaying disease progression.…

Sound · Computer Science 2026-02-09 Yifan Gao , Long Guo , Hong Liu

Given the great success of large language models (LLMs) across various tasks, in this paper, we introduce LLM-ST, a novel and effective speech translation model constructed upon a pre-trained LLM. By integrating the large language model…

Computation and Language · Computer Science 2023-12-22 Zhichao Huang , Rong Ye , Tom Ko , Qianqian Dong , Shanbo Cheng , Mingxuan Wang , Hang Li

Glaucoma is one of the major eye diseases that leads to progressive optic nerve fiber damage and irreversible blindness, afflicting millions of individuals. Glaucoma forecast is a good solution to early screening and intervention of…

Computer Vision and Pattern Recognition · Computer Science 2024-02-22 Xikai Yang , Jian Wu , Xi Wang , Yuchen Yuan , Ning Li Wang , Pheng-Ann Heng

Reinforcement learning (RL) has recently shown promise in predicting Alzheimer's disease (AD) progression due to its unique ability to model domain knowledge. However, it is not clear which RL algorithms are well-suited for this task.…

Recent advancements in deep learning (DL) have posed a significant challenge for automatic speech recognition (ASR). ASR relies on extensive training datasets, including confidential ones, and demands substantial computational and storage…

Sound · Computer Science 2024-04-19 Hamza Kheddar , Mustapha Hemis , Yassine Himeur

Alzheimer's disease (AD) stands as the predominant cause of dementia, characterized by a gradual decline in speech and language capabilities. Recent deep-learning advancements have facilitated automated AD detection through spontaneous…

Computation and Language · Computer Science 2024-09-20 Chin-Po Chen , Jeng-Lin Li

Alzheimer's disease (AD) is a neurodegenerative disease that affects nearly 50 million individuals across the globe and is one of the leading causes of deaths globally. It is projected that by 2050, the number of people affected by the…

Machine Learning · Computer Science 2021-10-26 Yash Kumar , Piyush Maheshwari , Shreyansh Joshi , Veeky Baths

People with heavy physical impairment such as amyotrophic lateral sclerosis (ALS) in a completely locked-in state (CLIS) suffer from inability to express their thoughts to others. To solve this problem, many brain-computer interface (BCI)…

Human-Computer Interaction · Computer Science 2020-04-24 Kuniaki Ozawa , Masayoshi Naito , Naoki Tanaka , Shiryu Wada

Autistic Spectrum Disorder (ASD) is a neurological disease characterized by difficulties with social interaction, communication, and repetitive activities. While its primary origin lies in genetics, early detection is crucial, and…

Machine Learning · Computer Science 2023-12-29 Rownak Ara Rasul , Promy Saha , Diponkor Bala , S M Rakib Ul Karim , Md. Ibrahim Abdullah , Bishwajit Saha