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Medical images and radiology reports are crucial for diagnosing medical conditions, highlighting the importance of quantitative analysis for clinical decision-making. However, the diversity and cross-source heterogeneity of these data…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Yutong Zhang , Yi Pan , Tianyang Zhong , Peixin Dong , Kangni Xie , Yuxiao Liu , Hanqi Jiang , Zhengliang Liu , Shijie Zhao , Tuo Zhang , Xi Jiang , Dinggang Shen , Tianming Liu , Xin Zhang

Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

Diabetic Retinopathy (DR) is a leading cause of vision loss globally. Yet despite its prevalence, the majority of affected people lack access to the specialized ophthalmologists and equipment required for assessing their condition. This can…

Computer Vision and Pattern Recognition · Computer Science 2021-10-22 Alexandros Papadopoulos , Fotis Topouzis , Anastasios Delopoulos

The 7-point checklist (7PCL) is a widely used diagnostic tool in dermoscopy for identifying malignant melanoma by assigning point values to seven specific attributes. However, the traditional 7PCL is limited to distinguishing between…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Yuheng Wang , Tianze Yu , Jiayue Cai , Sunil Kalia , Harvey Lui , Z. Jane Wang , Tim K. Lee

Interpretability is significant in computational pathology, leading to the development of multimodal information integration from histopathological image and corresponding text data.However, existing multimodal methods have limited…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Kangcheng Zhou , Jun Jiang , Qing Zhang , Shuang Zheng , Qingli Li , Shugong Xu

Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song

Digital pathology has recently been revolutionized by advancements in artificial intelligence, deep learning, and high-performance computing. With its advanced tools, digital pathology can help improve and speed up the diagnostic process,…

Image and Video Processing · Electrical Eng. & Systems 2024-03-28 Mohamed Elmanna , Ahmed Elsafty , Yomna Ahmed , Muhammad Rushdi , Ahmed Morsy

Deep convolutional neural networks(CNNs) have been successful for a wide range of computer vision tasks, including image classification. A specific area of the application lies in digital pathology for pattern recognition in the…

Image and Video Processing · Electrical Eng. & Systems 2020-08-10 Rasoul Sali , Sodiq Adewole , Lubaina Ehsan , Lee A. Denson , Paul Kelly , Beatrice C. Amadi , Lori Holtz , Syed Asad Ali , Sean R. Moore , Sana Syed , Donald E. Brown

Deep phenotyping is the detailed description of patient signs and symptoms using concepts from an ontology. The deep phenotyping of the numerous physician notes in electronic health records requires high throughput methods. Over the past…

Computation and Language · Computer Science 2024-03-12 Syed I. Munzir , Daniel B. Hier , Michael D. Carrithers

Medical images play a crucial role in modern healthcare by providing vital information for diagnosis, treatment planning, and disease monitoring. Fields such as radiology and pathology rely heavily on accurate image interpretation, with…

Image and Video Processing · Electrical Eng. & Systems 2024-08-06 H. R. Tizhoosh

In practice, clinicians achieve a diagnosis by following a sequence of steps, such as laboratory exams, observations, or imaging. The pathways to reach diagnosis decisions are documented by guidelines authored by expert organizations, which…

Computation and Language · Computer Science 2024-09-25 Elisa Castagnari , Lillian Muyama , Adrien Coulet

Recently, researchers, specialists, and companies around the world are rolling out deep learning and image processing-based systems that can fastly process hundreds of X-Ray and computed tomography (CT) images to accelerate the diagnosis of…

Image and Video Processing · Electrical Eng. & Systems 2020-04-01 Khalid El Asnaoui , Youness Chawki , Ali Idri

The computer-aided analysis of medical scans is a longstanding goal in the medical imaging field. Currently, deep learning has became a dominant methodology for supporting pathologists and radiologist. Deep learning algorithms have been…

Machine Learning · Computer Science 2017-12-06 Jakub M. Tomczak , Maximilian Ilse , Max Welling

We demonstrate a simple and effective automated method for the segmentation of glomeruli from large (~1 gigapixel) histopathological whole-slide images (WSIs) of thin renal tissue sections and biopsies, using an adaptation of the well-known…

Tissues and Organs · Quantitative Biology 2017-09-21 Olivier Simon , Rabi Yacoub , Sanjay Jain , Pinaki Sarder

The accurate classification of mass lesions in the adrenal glands (adrenal masses), detected with computed tomography (CT), is important for diagnosis and patient management. Adrenal masses can be benign or malignant and benign masses have…

Computer Vision and Pattern Recognition · Computer Science 2022-08-08 Lei Bi , Jinman Kim , Tingwei Su , Michael Fulham , David Dagan Feng , Guang Ning

Objective: Develop a cost-effective, large language model (LLM)-based pipeline for automatically extracting Review of Systems (ROS) entities from clinical notes. Materials and Methods: The pipeline extracts ROS section from the clinical…

Computation and Language · Computer Science 2026-05-15 Hieu Nghiem , Zhuqi Miao , Hemanth Reddy Singareddy , Jivan Lamichhane , Abdulaziz Ahmed , Johnson Thomas , Dursun Delen , William Paiva

Background: Type 2 diabetes mellitus (T2DM) is increasingly recognised as a systemic disease characterised by coordinated dysfunction across metabolic, renal, lipid, and inflammatory pathways. Existing clinical assessments often fail to…

Machine Learning · Computer Science 2026-05-26 Mini Han Wang , Liting Huang , Wei Hong , Boonthawan Wingwon

Despite being widely used to support clinical care, general-purpose large multimodal models (LMMs) have generally shown poor or inconclusive performance in medical image interpretation, particularly in pathology, where gigapixel images are…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Thomas A. Buckley , Kian R. Weihrauch , Katherine Latham , Andrew Z. Zhou , Padmini A. Manrai , Arjun K. Manrai

Recent advances in reasoning with large language models (LLMs)has shown remarkable reasoning capabilities in domains such as mathematics and coding, yet their application to clinical diagnosis remains underexplored. Here, we introduce…

Computation and Language · Computer Science 2025-04-16 Wuyang Lan , Wenzheng Wang , Changwei Ji , Guoxing Yang , Yongbo Zhang , Xiaohong Liu , Song Wu , Guangyu Wang

With over 200 million published academic documents and millions of new documents being written each year, academic researchers face the challenge of searching for information within this vast corpus. However, existing retrieval systems…

Information Retrieval · Computer Science 2024-05-21 Gengchen Wei , Xinle Pang , Tianning Zhang , Yu Sun , Xun Qian , Chen Lin , Han-Sen Zhong , Wanli Ouyang
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