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Colorectal liver metastases (CRLM) are a major cause of cancer-related mortality, and reliable detection on CT remains challenging in multi-centre settings. We developed a foundation model-based AI pipeline for patient-level classification…

Assessing coronary artery plaque segments in coronary CT angiography scans is an important task to improve patient management and clinical outcomes, as it can help to decide whether invasive investigation and treatment are necessary. In…

Diagnosing diseases such as leukemia or anemia requires reliable counts of blood cells. Hematologists usually label and count microscopy images of blood cells manually. In many cases, however, cells in different maturity states are…

Machine Learning · Computer Science 2020-07-13 Yushan Liu , Markus M. Geipel , Christoph Tietz , Florian Buettner

In practice, clinicians achieve a diagnosis by following a sequence of steps, such as laboratory exams, observations, or imaging. The pathways to reach diagnosis decisions are documented by guidelines authored by expert organizations, which…

Computation and Language · Computer Science 2024-09-25 Elisa Castagnari , Lillian Muyama , Adrien Coulet

Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ravi Mosalpuri , Mohammed Abdelsamea , Ahmed Karam Eldaly

Automated blood morphology analysis can support hematological diagnostics in low- and middle-income countries (LMICs) but remains sensitive to dataset shifts from staining variability, imaging differences, and rare morphologies. Building…

Machine Learning · Computer Science 2026-01-08 Gabriel Ansah , Eden Ruffell , Delmiro Fernandez-Reyes , Petru Manescu

Brain tumor is one of the leading causes of cancer-related death globally among children and adults. Precise classification of brain tumor grade (low-grade and high-grade glioma) at early stage plays a key role in successful prognosis and…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Ruqian Hao , Khashayar Namdar , Lin Liu , Farzad Khalvati

Full-Field Digital Mammography (FFDM) is the primary imaging modality for routine breast cancer screening; however, its effectiveness is limited in patients with dense breast tissue or fibrocystic conditions. Contrast-Enhanced Spectral…

Image and Video Processing · Electrical Eng. & Systems 2026-02-16 Aurora Rofena , Claudia Lucia Piccolo , Bruno Beomonte Zobel , Paolo Soda , Valerio Guarrasi

Multi-class cell nuclei detection is a fundamental prerequisite in the diagnosis of histopathology. It is critical to efficiently locate and identify cells with diverse morphology and distributions in digital pathological images. Most…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Junjia Huang , Haofeng Li , Xiang Wan , Guanbin Li

Melanoma is the deadliest form of skin cancer. While curable with early detection, only highly trained specialists are capable of accurately recognizing the disease. As expertise is in limited supply, automated systems capable of…

Computer Vision and Pattern Recognition · Computer Science 2016-10-19 Noel Codella , Quoc-Bao Nguyen , Sharath Pankanti , David Gutman , Brian Helba , Allan Halpern , John R. Smith

The pathogenesis and progression of many tumors, including hematologic malignancies is highly dependent on enhanced lipogenesis. De novo fatty-acid synthesis permits accelerated proliferation of tumor cells by providing structural…

Tissues and Organs · Quantitative Biology 2016-12-04 Christian Thiede , Gerhard Ehninger , Kai Simons , Michal Grzybek , Adam Stefanko

Intraoperative visualization of hemodynamics is crucial for accurate diagnosis and informed surgical decision-making. In neurosurgery, indocyanine green fluorescence imaging (ICG-FI) is the gold standard for assessing blood flow and…

Medical Physics · Physics 2025-10-20 Yan Shi , Denghui Zhao , Jingyi Yu , Wei Ni , Pengcheng Li , Yun Gu , Peng Miao , Shanbao Tong

Automatic identification of patients with luminal and non-luminal subtypes during a routine mammography screening can support clinicians in streamlining breast cancer therapy planning. Recent machine learning techniques have shown promising…

Image and Video Processing · Electrical Eng. & Systems 2023-01-24 Adarsh Bhandary Panambur , Prathmesh Madhu , Andreas Maier

Circulating tumor cells (CTCs) are crucial biomarkers in liquid biopsy, offering a noninvasive tool for cancer patient management. However, their identification remains particularly challenging due to their limited number and heterogeneity.…

Image and Video Processing · Electrical Eng. & Systems 2025-11-24 Martina Russo , Giulia Bertolini , Vera Cappelletti , Cinzia De Marco , Serena Di Cosimo , Petra Paiè , Nadia Brancati

Anemia is a widespread global health issue, particularly among young children in low-resource settings. Traditional methods for anemia detection often require expensive equipment and expert knowledge, creating barriers to early and accurate…

Image and Video Processing · Electrical Eng. & Systems 2025-07-22 Sebastian A. Cruz Romero , Wilfredo E. Lugo Beauchamp

Glaucoma is the second driving reason for partial or complete blindness among all the visual deficiencies which mainly occurs because of excessive pressure in the eye due to anxiety or depression which damages the optic nerve and creates…

Computer Vision and Pattern Recognition · Computer Science 2022-10-10 Touhidul Islam Chayan , Anita Islam , Eftykhar Rahman , Md. Tanzim Reza , Tasnim Sakib Apon , MD. Golam Rabiul Alam

We present a machine learning method capable of accurately detecting chromosome abnormalities that cause blood cancers directly from microscope images of the metaphase stage of cell division. The pipeline is built on a series of fine-tuned…

Diabetes is a major health problem in both developing and developed countries and its incidence is rising dramatically. In this study, we investigate a novel automatic approach to diagnose Diabetes disease based on Feature Weighted Support…

Machine Learning · Computer Science 2012-01-12 Davar Giveki , Hamid Salimi , GholamReza Bahmanyar , Younes Khademian

Fetal health classification is a critical task in obstetrics, enabling early identification and management of potential health problems. However, it remains challenging due to data complexity and limited labeled samples. This research paper…

Machine Learning · Computer Science 2024-09-09 Sujith K Mandala

During the last years, computer vision-based diagnosis systems have been widely used in several hospitals and dermatology clinics, aiming at the early detection of malignant melanoma tumor, which is among the most frequent types of skin…

Computer Vision and Pattern Recognition · Computer Science 2021-06-09 Mahammed Messadi , Hocine Cherifi , Abdelhafid Bessaid