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Early diagnosis of interstitial lung diseases is crucial for their treatment, but even experienced physicians find it difficult, as their clinical manifestations are similar. In order to assist with the diagnosis, computer-aided diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2016-12-13 Stergios Christodoulidis , Marios Anthimopoulos , Lukas Ebner , Andreas Christe , Stavroula Mougiakakou

Detection of pulmonary nodules on chest CT is an essential step in the early diagnosis of lung cancer, which is critical for best patient care. Although a number of computer-aided nodule detection methods have been published in the…

Computer Vision and Pattern Recognition · Computer Science 2018-07-03 Junjie Zhang , Yong Xia , Yanning Zhang

Accurate lung nodule detection for computed tomography (CT) scan imagery is challenging in real-world settings due to the sparse occurrence of nodules and similarity to other anatomical structures. In a typical positive case, nodules may…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Hooman Ramezani , Dionne Aleman , Daniel Létourneau

Early detection of lung cancer has been proven to decrease mortality significantly. A recent development in computed tomography (CT), spectral CT, can potentially improve diagnostic accuracy, as it yields more information per scan than…

Computer Vision and Pattern Recognition · Computer Science 2020-07-01 Linde S. Hesse , Pim A. de Jong , Josien P. W. Pluim , Veronika Cheplygina

Lung cancer remains one of the leading causes of cancer-related mortality worldwide, with early and accurate diagnosis playing a pivotal role in improving patient outcomes. Automated detection of pulmonary nodules in computed tomography…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Abhinav Roy , Bhavesh Gyanchandani , Aditya Oza

Densely annotated medical image datasets that capture not only diagnostic labels but also the underlying reasoning behind these diagnoses are scarce. Such reasoning-related annotations are essential for developing and evaluating explainable…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Luisa Gallée , Yiheng Xiong , Meinrad Beer , Michael Götz

The state of the art lung nodule detection studies rely on computationally expensive multi-stage frameworks to detect nodules from CT scans. To address this computational challenge and provide better performance, in this paper we propose…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Naji Khosravan , Ulas Bagci

Candidate generation, the first stage for most computer aided detection (CAD) systems, rapidly scans the entire image data for any possible abnormality locations, while the subsequent stages of the CAD system refine the candidates list to…

Image and Video Processing · Electrical Eng. & Systems 2019-07-22 Sergei V. Fotin , David F. Yankelevitz , Claudia I. Henschke , Anthony P. Reeves

Quantum Machine Learning (QML) is a red-hot field that brings novel discoveries and exciting opportunities to resolve, speed up, or refine the analysis of a wide range of computational problems. In the realm of biomedical research and…

Machine Learning · Computer Science 2024-10-04 Mandeep Kaur Saggi , Amandeep Singh Bhatia , Mensah Isaiah , Humaira Gowher , Sabre Kais

Lung cancer is deadly cancer that causes millions of deaths every year around the world. Accurate lung nodule detection and segmentation in computed tomography (CT) images is the most important part of diagnosing lung cancer in the early…

Image and Video Processing · Electrical Eng. & Systems 2021-10-12 Syeda Furruka Banu , Md. Mostafa Kamal Sarker , Mohamed Abdel-Nasser , Domenec Puig , Hatem A. Raswan

This paper introduces a novel deep-learning method for the automatic detection and segmentation of lung nodules, aimed at advancing the accuracy of early-stage lung cancer diagnosis. The proposed approach leverages a unique "Channel Squeeze…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mingxiu Sui , Jiacheng Hu , Tong Zhou , Zibo Liu , Likang Wen , Junliang Du

The limited sample size and insufficient diversity of lung nodule CT datasets severely restrict the performance and generalization ability of detection models. Existing methods generate images with insufficient diversity and…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lu Cao , Xiquan He , Junying Zeng , Chaoyun Mai , Min Luo

Evaluation of artificial intelligence (AI) models for low-dose CT lung cancer screening is limited by heterogeneous datasets, annotation standards, and evaluation protocols, making performance difficult to compare and translate across…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Fakrul Islam Tushar , Avivah Wang , Lavsen Dahal , Ehsan Samei , Michael R. Harowicz , Jayashree Kalpathy-Cramer , Kyle J. Lafata , Tina D. Tailor , Cynthia Rudin , Joseph Y. Lo

This paper deals with the multiple annotation problem in medical application of cancer detection in digital images. The main assumption is that though images are labeled by many experts, the number of images read by the same expert is not…

Computer Vision and Pattern Recognition · Computer Science 2014-12-10 Inna Stainvas , Alexandra Manevitch , Isaac Leichter

Early detection of lung cancer is an effective way to improve the survival rate of patients. It is a critical step to have accurate detection of lung nodules in computed tomography (CT) images for the diagnosis of lung cancer. However, due…

Computer Vision and Pattern Recognition · Computer Science 2019-05-10 Haichao Cao , Hong Liu , Enmin Song , Guangzhi Ma , Xiangyang Xu , Renchao Jin , Tengying Liu , Chih-Cheng Hung

Remarkable progress has been made in image recognition, primarily due to the availability of large-scale annotated datasets and the revival of deep CNN. CNNs enable learning data-driven, highly representative, layered hierarchical image…

Computer Vision and Pattern Recognition · Computer Science 2016-02-11 Hoo-Chang Shin , Holger R. Roth , Mingchen Gao , Le Lu , Ziyue Xu , Isabella Nogues , Jianhua Yao , Daniel Mollura , Ronald M. Summers

Lung cancer, particularly in its advanced stages, remains a leading cause of death globally. Though early detection via low-dose computed tomography (CT) is promising, the identification of high-risk factors crucial for surgical mode…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Xiaotong Fu , Xiangyu Meng , Jing Zhou , Ying Ji

Lung diseases including infections such as Pneumonia, Tuberculosis, and novel Coronavirus (COVID-19), together with Lung Cancer are significantly widespread and are, typically, considered life threatening. In particular, lung cancer is…

Image and Video Processing · Electrical Eng. & Systems 2020-08-17 Parnian Afshar , Farnoosh Naderkhani , Anastasia Oikonomou , Moezedin Javad Rafiee , Arash Mohammadi , Konstantinos N. Plataniotis

Rationale: Computer aided detection (CAD) algorithms for Pulmonary Embolism (PE) algorithms have been shown to increase radiologists' sensitivity with a small increase in specificity. However, CAD for PE has not been adopted into clinical…

The recent development of imaging and sequencing technologies enables systematic advances in the clinical study of lung cancer. Meanwhile, the human mind is limited in effectively handling and fully utilizing the accumulation of such…

Machine Learning · Computer Science 2022-03-29 Yawei Li , Xin Wu , Ping Yang , Guoqian Jiang , Yuan Luo