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We introduce a new computer aided detection and diagnosis system for lung cancer screening with low-dose CT scans that produces meaningful probability assessments. Our system is based entirely on 3D convolutional neural networks and…

Computer Vision and Pattern Recognition · Computer Science 2020-01-22 Onur Ozdemir , Rebecca L. Russell , Andrew A. Berlin

The use of automatic systems in the analysis of medical images has proven to be very useful to radiologists, especially in the framework of screening programs, in which radiologists make their first diagnosis on the basis of images only,…

Lung cancer is the commonest cause of cancer deaths worldwide, and its mortality can be reduced significantly by performing early diagnosis and screening. Since the 1960s, driven by the pressing needs to accurately and effectively interpret…

Computer Vision and Pattern Recognition · Computer Science 2020-04-27 Bo Liu , Wenhao Chi , Xinran Li , Peng Li , Wenhua Liang , Haiping Liu , Wei Wang , Jianxing He

Lung cancer is one of the death threatening diseases among human beings. Early and accurate detection of lung cancer can increase the survival rate from lung cancer. Computed Tomography (CT) images are commonly used for detecting the lung…

Machine Learning · Statistics 2019-11-26 Md Rashidul Hasan , Muntasir Al Kabir

Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Junhua Chen , Haiyan Zeng , Chong Zhang , Zhenwei Shi , Andre Dekker , Leonard Wee , Inigo Bermejo

The field of Machine Learning, a subset of Artificial Intelligence, has led to remarkable advancements in many areas, including medicine. Machine Learning algorithms require large datasets to train computer models successfully. Although…

Image and Video Processing · Electrical Eng. & Systems 2019-12-30 Andrew A. Borkowski , Marilyn M. Bui , L. Brannon Thomas , Catherine P. Wilson , Lauren A. DeLand , Stephen M. Mastorides

In this work, we present a fully automated lung computed tomography (CT) cancer diagnosis system, DeepLung. DeepLung consists of two components, nodule detection (identifying the locations of candidate nodules) and classification…

Computer Vision and Pattern Recognition · Computer Science 2018-01-30 Wentao Zhu , Chaochun Liu , Wei Fan , Xiaohui Xie

Early detection of lung cancer is crucial for effective treatment and relies on accurate volumetric assessment of pulmonary nodules in CT scans. Traditional methods, such as consolidation-to-tumor ratio (CTR) and spherical approximation,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Yihan Zhou , Haocheng Huang , Yue Yu , Jianhui Shang

Detecting malignant pulmonary nodules at an early stage can allow medical interventions which may increase the survival rate of lung cancer patients. Using computer vision techniques to detect nodules can improve the sensitivity and the…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Siqi Liu , Arnaud Arindra Adiyoso Setio , Florin C. Ghesu , Eli Gibson , Sasa Grbic , Bogdan Georgescu , Dorin Comaniciu

Early detection of lung nodules with computed tomography (CT) is critical for the longer survival of lung cancer patients and better quality of life. Computer-aided detection/diagnosis (CAD) is proven valuable as a second or concurrent…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Chuang Niu , Ge Wang

Recent evolution in deep learning has proven its value for CT-based lung nodule classification. Most current techniques are intrinsically black-box systems, suffering from two generalizability issues in clinical practice. First,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-28 Hanxiao Zhang , Liang Chen , Xiao Gu , Minghui Zhang , Yulei Qin , Feng Yao , Zhexin Wang , Yun Gu , Guang-Zhong Yang

Machine learning models have utilized semantic features, deep features, or both to assess lung nodule malignancy. However, their reliance on manual annotation during inference, limited interpretability, and sensitivity to imaging variations…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Luoting Zhuang , Seyed Mohammad Hossein Tabatabaei , Ramin Salehi-Rad , Linh M. Tran , Denise R. Aberle , Ashley E. Prosper , William Hsu

Lung cancer, a malignancy originating in lung tissues, is commonly diagnosed and classified using medical imaging techniques, particularly computed tomography (CT). Despite the integration of machine learning and deep learning methods, the…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Olajumoke O. Adekunle , Joseph D. Akinyemi , Khadijat T. Ladoja , Olufade F. W. Onifade

Deep learning, as a promising new area of machine learning, has attracted a rapidly increasing attention in the field of medical imaging. Compared to the conventional machine learning methods, deep learning requires no hand-tuned feature…

Quantitative Methods · Quantitative Biology 2016-11-29 He Yang , Hengyong Yu , Ge Wang

Lung cancer is the leading cause of cancer-related deaths in the past several years. A major challenge in lung cancer screening is the detection of lung nodules from computed tomography (CT) scans. State-of-the-art approaches in automated…

Computer Vision and Pattern Recognition · Computer Science 2018-10-05 Aryan Mobiny , Hien Van Nguyen

The 3D simulation model of the lung was established by using the reconstruction method. A computer aided pulmonary nodule detection model was constructed. The process iterates over the images to refine the lung nodule recognition model…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Yutian Yang , Hongjie Qiu , Yulu Gong , Xiaoyi Liu , Yang Lin , Muqing Li

Computer-aided diagnosis (CAD) technology can assist clinicians in evaluating liver lesions and intervening with treatment in time. Although CAD technology has advanced in recent years, the application scope of existing datasets remains…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Zhe Liu , Kai Han , Siqi Ma , Yan Zhu , Jun Chen , Chongwen Lyu , Xinyi Qiu , Chengxuan Qian , Yuqing Song , Yi Liu , Liyuan Tian , Yang Ji , Yuefeng Li

Lung cancer has been one of the major threats across the world with the highest mortalities. Computer-aided detection (CAD) can help in early detection and thus can help increase the survival rate. Accurate lung parenchyma segmentation (to…

Image and Video Processing · Electrical Eng. & Systems 2025-09-18 Muhammad Abdullah , Furqan Shaukat

Recent studies have shown that lung cancer screening using annual low-dose computed tomography (CT) reduces lung cancer mortality by 20% compared to traditional chest radiography. Therefore, CT lung screening has started to be used widely…

Image and Video Processing · Electrical Eng. & Systems 2021-07-13 Gorkem Polat , Yesim Dogrusoz Serinagaoglu , Ugur Halici