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Datasets used for molecular docking, such as PDBBind, contain technical variability - they are noisy. Although the origins of the noise have been discussed, a comprehensive analysis of the physical, chemical, and bioactivity characteristics…

Machine Learning · Computer Science 2024-10-02 Ahmet Sarigun , Vedran Franke , Bora Uyar , Altuna Akalin

Key-value stores underpin a wide range of applications due to their simplicity and efficiency. Log-Structured Merge Trees (LSM-trees) dominate as their underlying structure, excelling at handling rapidly growing data. Recent research has…

Databases · Computer Science 2026-01-29 Junfeng Liu , Haoxuan Xie , Siqiang Luo

Key-Value Stores (KVS) based on log-structured merge-trees (LSM-trees) are widely used in storage systems but face significant challenges, such as high write amplification caused by compaction. KV-separated LSM-trees address write…

Databases · Computer Science 2025-08-20 Jianshun Zhang , Fang Wang , Jiaxin Ou , Yi Wang , Ming Zhao , Sheng Qiu , Junxun Huang , Baoquan Li , Peng Fang , Dan Feng

Modern hash table designs strive to minimize space while maximizing speed. The most important factor in speed is the number of cache lines accessed during updates and queries. This is especially important on PMEM, which is slower than DRAM…

Data Structures and Algorithms · Computer Science 2022-10-13 Prashant Pandey , Michael A. Bender , Alex Conway , Martín Farach-Colton , William Kuszmaul , Guido Tagliavini , Rob Johnson

We propose BS-tree, an in-memory implementation of the B+-tree that adopts the structure of the disk-based index (i.e., a balanced, multiway tree), setting the node size to a memory block that can be processed fast and in parallel using…

Databases · Computer Science 2025-11-14 Dimitrios Tsitsigkos , Achilleas Michalopoulos , Nikos Mamoulis , Manolis Terrovitis

We present~\emph{KV-Tandem}, a modular architecture for building LSM-based storage engines on top of simple, non-ordered persistent key-value stores (KVSs). KV-Tandem enables advanced functionalities such as range queries and snapshot…

Compaction is a necessary, but often costly background process in write-optimized data structures like LSM-trees that reorganizes incoming data that is sequentially appended to logs. In this paper, we introduce Transformation-Embedded…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-11 Holly Casaletto , Jeff Lefevre , Aldrin Montana , Peter Alvaro

Consistent hashing (CH) is a central building block in many networking applications, from datacenter load-balancing to distributed storage. Unfortunately, state-of-the-art CH solutions cannot ensure full consistency under arbitrary changes…

Data Structures and Algorithms · Computer Science 2020-11-24 Gal Mendelson , Shay Vargaftik , Katherine Barabash , Dean Lorenz , Isaac Keslassy , Ariel Orda

Most cloud services and distributed applications rely on hashing algorithms that allow dynamic scaling of a robust and efficient hash table. Examples include AWS, Google Cloud and BitTorrent. Consistent and rendezvous hashing are algorithms…

Data Structures and Algorithms · Computer Science 2022-05-17 Mike Heddes , Igor Nunes , Tony Givargis , Alexandru Nicolau , Alex Veidenbaum

Emerging technologies present opportunities for system designers to meet the challenges presented by competing trends of big data analytics and limitations on CMOS scaling. Specifically, memristors are an emerging high-density technology…

Emerging Technologies · Computer Science 2016-01-21 Yang Liu , Chris Dwyer , Alvin R. Lebeck

Recently, crossbar array based in-memory accelerators have been gaining interest due to their high throughput and energy efficiency. While software and compiler support for the in-memory accelerators has also been introduced, they are…

Hardware Architecture · Computer Science 2025-01-14 Jihoon Park , Jeongin Choe , Dohyun Kim , Jae-Joon Kim

Storing tabular data to balance storage and query efficiency is a long-standing research question in the database community. In this work, we argue and show that a novel DeepMapping abstraction, which relies on the impressive memorization…

Databases · Computer Science 2024-09-27 Lixi Zhou , K. Selçuk Candan , Jia Zou

Given a set $S$ of $n$ keys, a perfect hash function for $S$ maps the keys in $S$ to the first $m \geq n$ integers without collisions. It may return an arbitrary result for any key not in $S$ and is called minimal if $m = n$. The most…

Data Structures and Algorithms · Computer Science 2026-02-06 Hans-Peter Lehmann , Thomas Mueller , Rasmus Pagh , Giulio Ermanno Pibiri , Peter Sanders , Sebastiano Vigna , Stefan Walzer

The rise of compound AI serving that integrates multiple operators in a pipeline enables end-user applications such as generative AI-powered meeting companions, autonomous driving, and immersive gaming. These workloads span diverse…

Databases · Computer Science 2026-05-19 Banruo Liu , Wei-Yu Lin , Minghao Fang , Yihan Jiang , Fan Lai

Retrieving data from large-scale source code archives is vital for AI training, neural-based software analysis, and information retrieval, to cite a few. This paper studies and experiments with the design of a compressed key-value store for…

Data Structures and Algorithms · Computer Science 2026-01-21 Paolo Ferragina , Francesco Tosoni

Modern large language models (LLMs) place extraordinary pressure on memory and compute budgets, making principled compression indispensable for both deployment and continued training. We present Hierarchical Sparse Plus Low-Rank (HSS)…

Machine Learning · Computer Science 2026-01-14 Pawan Kumar , Aditi Gupta

We introduce NeuralVDB, which improves on an existing industry standard for efficient storage of sparse volumetric data, denoted VDB [Museth 2013], by leveraging recent advancements in machine learning. Our novel hybrid data structure can…

Machine Learning · Computer Science 2024-02-13 Doyub Kim , Minjae Lee , Ken Museth

The Intel Optane DC Persistent Memory (DCPM) is an attractive novel technology for building storage systems for data intensive HPC applications, as it provides lower cost per byte, low standby power and larger capacities than DRAM, with…

Key-value stores are a fundamental class of NoSQL databases that offer a simple yet powerful model for data storage and retrieval, representing information as pairs of unique keys and associated values. Their minimal structure enables…

Databases · Computer Science 2025-11-13 Zonglin Guo , Tony Givargis

Index structures are one of the most important tools that DBAs leverage to improve the performance of analytics and transactional workloads. However, building several indexes over large datasets can often become prohibitive and consume…

Databases · Computer Science 2020-03-26 Alex Galakatos , Michael Markovitch , Carsten Binnig , Rodrigo Fonseca , Tim Kraska