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The last decade of machine learning has seen drastic increases in scale and capabilities. Deep neural networks (DNNs) are increasingly being deployed in the real world. However, they are difficult to analyze, raising concerns about using…

Machine Learning · Computer Science 2023-08-22 Tilman Räuker , Anson Ho , Stephen Casper , Dylan Hadfield-Menell

Despite the remarkable performance, Deep Neural Networks (DNNs) behave as black-boxes hindering user trust in Artificial Intelligence (AI) systems. Research on opening black-box DNN can be broadly categorized into post-hoc methods and…

Machine Learning · Computer Science 2021-06-25 Sandareka Wickramanayake , Wynne Hsu , Mong Li Lee

Deep Reinforcement Learning (DRL) has achieved remarkable success in sequential decision-making tasks across diverse domains, yet its reliance on black-box neural architectures hinders interpretability, trust, and deployment in high-stakes…

Machine Learning · Computer Science 2025-02-12 Zelei Cheng , Jiahao Yu , Xinyu Xing

Computationally explicit hypotheses of brain function derived from machine learning (ML)-based models have recently revolutionized neuroscience. Despite the unprecedented ability of these artificial neural networks (ANNs) to capture…

Neurons and Cognition · Quantitative Biology 2023-12-12 Kohitij Kar , Simon Kornblith , Evelina Fedorenko

The objective of this proposal is to bridge the gap between Deep Learning (DL) and System Dynamics (SD) by developing an interpretable neural system dynamics framework. While DL excels at learning complex models and making accurate…

Machine Learning · Computer Science 2025-05-21 Riccardo D'Elia

Interpretability of Deep Learning (DL) is a barrier to trustworthy AI. Despite great efforts made by the Explainable AI (XAI) community, explanations lack robustness -- indistinguishable input perturbations may lead to different XAI…

Machine Learning · Computer Science 2023-08-01 Wei Huang , Xingyu Zhao , Gaojie Jin , Xiaowei Huang

Neural networks are widely regarded as black-box models, creating significant challenges in understanding their inner workings, especially in natural language processing (NLP) applications. To address this opacity, model explanation…

Computation and Language · Computer Science 2025-01-10 Melkamu Mersha , Mingiziem Bitewa , Tsion Abay , Jugal Kalita

Machine learning (ML) has seen enormous consideration during the most recent decade. This success started in 2012 when an ML model accomplished a remarkable triumph in the ImageNet Classification, the world's most famous competition for…

Image and Video Processing · Electrical Eng. & Systems 2022-02-18 Imran Ul Haq

The adoption of Deep Learning algorithms in the medical imaging field is a prominent area of research, with high potential for advancing AI-based Computer-aided diagnosis (AI-CAD) solutions. However, current solutions face challenges due to…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Iury B. de A. Santos , André C. P. L. F. de Carvalho

With the growing adoption of AI-based systems across everyday life, the need to understand their decision-making mechanisms is correspondingly increasing. The level at which we can trust the statistical inferences made from AI-based…

Machine Learning · Statistics 2024-04-15 Adam Spannaus , Heidi A. Hanson , Lynne Penberthy , Georgia Tourassi

Accurate diagnosis of Autism Spectrum Disorder (ASD) followed by effective rehabilitation is essential for the management of this disorder. Artificial intelligence (AI) techniques can aid physicians to apply automatic diagnosis and…

Machine learning (ML) has seen significant growth in both popularity and importance. The high prediction accuracy of ML models is often achieved through complex black-box architectures that are difficult to interpret. This interpretability…

Machine Learning · Statistics 2024-07-29 David Köhler , David Rügamer , Matthias Schmid

Deep learning methods, in particular convolutional neural networks, have emerged as a powerful tool in medical image computing tasks. While these complex models provide excellent performance, their black-box nature may hinder real-world…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Yuzhe Lu , Adam Perer

Deep learning models are favored in many research and industry areas and have reached the accuracy of approximating or even surpassing human level. However they've long been considered by researchers as black-box models for their…

Machine Learning · Computer Science 2020-10-16 Xiaojian Wang , Jingyuan Wang , Ke Tang

Explainable AI has emerged to be a key component for black-box machine learning approaches in domains with a high demand for reliability or transparency. Examples are medical assistant systems, and applications concerned with the General…

Machine Learning · Computer Science 2021-05-18 Johannes Rabold , Gesina Schwalbe , Ute Schmid

Deep learning-based AI models have been extensively applied in genomics, achieving remarkable success across diverse applications. As these models gain prominence, there exists an urgent need for interpretability methods to establish…

Genomics · Quantitative Biology 2025-05-16 Chenyu Wang , Chaoying Zuo , Zihan Su , Yuhang Xing , Lu Li , Maojun Wang , Zeyu Zhang

This paper explores interpretability techniques for two of the most successful learning algorithms in medical decision-making literature: deep neural networks and random forests. We applied these algorithms in a real-world medical dataset…

Machine Learning · Computer Science 2020-02-24 Catarina Moreira , Renuka Sindhgatta , Chun Ouyang , Peter Bruza , Andreas Wichert

Deep learning is increasingly used as a building block of security systems. Unfortunately, neural networks are hard to interpret and typically opaque to the practitioner. The machine learning community has started to address this problem by…

Machine Learning · Computer Science 2020-04-28 Alexander Warnecke , Daniel Arp , Christian Wressnegger , Konrad Rieck

Deep learning methods have recently made notable advances in the tasks of classification and representation learning. These tasks are important for brain imaging and neuroscience discovery, making the methods attractive for porting to a…

Neural and Evolutionary Computing · Computer Science 2014-02-20 Sergey M. Plis , Devon R. Hjelm , Ruslan Salakhutdinov , Vince D. Calhoun

To learn about real world phenomena, scientists have traditionally used models with clearly interpretable elements. However, modern machine learning (ML) models, while powerful predictors, lack this direct elementwise interpretability (e.g.…

Machine Learning · Statistics 2024-07-16 Timo Freiesleben , Gunnar König , Christoph Molnar , Alvaro Tejero-Cantero