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Clinical trials are fundamental in developing new drugs, medical devices, and treatments. However, they are often time-consuming and have low success rates. Although there have been initial attempts to create large language models (LLMs)…

Computation and Language · Computer Science 2024-07-17 Jiacheng Lin , Hanwen Xu , Zifeng Wang , Sheng Wang , Jimeng Sun

In our study, we evaluated large language model (LLM) performance on pharmacy licensure-style question-answering tasks and developed an external knowledge integration method to improve accuracy. We benchmarked ten LLMs with varying…

Functional evidence is essential for clinical interpretation of genomic variants, but identifying relevant studies and translating experimental results into structured evidence remains labor intensive. We developed a benchmark based on…

Genomics · Quantitative Biology 2026-04-02 Ali Saadat , Jacques Fellay

Large language models (LLMs) have saturated standard medical benchmarks that test factual recall, yet their ability to perform higher-order reasoning, such as synthesizing evidence from multiple sources, remains critically under-explored.…

Computation and Language · Computer Science 2026-05-12 Huy Hoang Ha , Benoit Favre , Francois Portet

This study provides the first comprehensive assessment of consistency and reproducibility in Large Language Model (LLM) outputs in finance and accounting research. We evaluate how consistently LLMs produce outputs given identical inputs…

General Finance · Quantitative Finance 2025-09-16 Julian Junyan Wang , Victor Xiaoqi Wang

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta

The increasing prevalence of retinal diseases poses a significant challenge to the healthcare system, as the demand for ophthalmologists surpasses the available workforce. This imbalance creates a bottleneck in diagnosis and treatment,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-15 Jia-Hong Huang

Clinical coding is crucial for healthcare billing and data analysis. Manual clinical coding is labour-intensive and error-prone, which has motivated research towards full automation of the process. However, our analysis, based on US English…

Computation and Language · Computer Science 2025-06-19 Yidong Gan , Maciej Rybinski , Ben Hachey , Jonathan K. Kummerfeld

We propose a learning analytics-based methodology for assessing the collaborative writing of humans and generative artificial intelligence. Framed by the evidence-centered design, we used elements of knowledge-telling, knowledge…

Human-Computer Interaction · Computer Science 2024-01-18 Yixin Cheng , Kayley Lyons , Guanliang Chen , Dragan Gasevic , Zachari Swiecki

Being able to effectively read scientific plots, or chart understanding, is a central part toward building effective agents for science. However, existing multimodal large language models (MLLMs), especially open-source ones, are still…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Yuwei Yang , Zeyu Zhang , Yunzhong Hou , Zhuowan Li , Gaowen Liu , Ali Payani , Yuan-Sen Ting , Liang Zheng

Systematic reviews, which entail the extraction of data from large numbers of scientific documents, are an ideal avenue for the application of machine learning. They are vital to many fields of science and philanthropy, but are very…

Computation and Language · Computer Science 2020-10-12 Seraphina Goldfarb-Tarrant , Alexander Robertson , Jasmina Lazic , Theodora Tsouloufi , Louise Donnison , Karen Smyth

Recent advancements in large language models have sparked interest in utilizing them to aid the peer review process of scientific publication amid the peer review crisis. However, having AI models generate full reviews in the same way as…

Computation and Language · Computer Science 2026-04-03 Tianmai M. Zhang , Neil F. Abernethy

Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

Artificial Intelligence · Computer Science 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

AI and generative AI tools, including chatbots like ChatGPT that rely on large language models (LLMs), have burst onto the scene this year, creating incredible opportunities to increase work productivity and improve our lives. Statisticians…

Computation and Language · Computer Science 2024-03-27 Mark Glickman , Yi Zhang

Large language model (LLM) based task plans and corresponding human demonstrations for embodied AI may be noisy, with unnecessary actions, redundant navigation, and logical errors that reduce policy quality. We propose an iterative…

Artificial Intelligence · Computer Science 2026-01-01 Ananth Hariharan , Vardhan Dongre , Dilek Hakkani-Tür , Gokhan Tur

Modern AI progress has been driven by ML methods that are generalizable across settings and scalable to larger regimes. As large language models demonstrate advanced capabilities in reasoning, coding, and engineering tasks, it is…

Current medical language models, adapted from large language models (LLMs), typically predict ICD code-based diagnosis from electronic health records (EHRs) because these labels are readily available. However, ICD codes do not capture the…

Computation and Language · Computer Science 2025-12-09 Wenhao Li , Hongkuan Zhang , Hongwei Zhang , Zhengxu Li , Zengjie Dong , Yafan Chen , Niranjan Bidargaddi , Hong Liu

Objective: Clinical trials are essential for advancing pharmaceutical interventions, but they face a bottleneck in selecting eligible participants. Although leveraging electronic health records (EHR) for recruitment has gained popularity,…

Computation and Language · Computer Science 2026-01-15 Mojdeh Rahmanian , Seyed Mostafa Fakhrahmad , Seyedeh Zahra Mousavi

Background: Recruitment for cohorts involving complex liver diseases, such as hepatocellular carcinoma and liver cirrhosis, often requires interpreting semantically complex criteria. Traditional manual screening methods are time-consuming…

Artificial Intelligence · Computer Science 2025-02-27 Xiongbin Gui , Hanlin Lv , Xiao Wang , Longting Lv , Yi Xiao , Lei Wang

Systematic literature reviews are the highest quality of evidence in research. However, the review process is hindered by significant resource and data constraints. The Literature Review Network (LRN) is the first of its kind explainable AI…

Digital Libraries · Computer Science 2024-08-13 Joshua Morriss , Tod Brindle , Jessica Bah Rösman , Daniel Reibsamen , Andreas Enz
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