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This article proposes a novel Bayesian classification framework for networks with labeled nodes. While literature on statistical modeling of network data typically involves analysis of a single network, the recent emergence of complex data…

Methodology · Statistics 2020-09-25 Sharmistha Guha , Abel Rodriguez

Genetic regulatory networks with adaptive responses are widely studied in biology. Usually, models consisting only of a few nodes have been considered. They present one input receptor for activation and one output node where the adaptive…

Molecular Networks · Quantitative Biology 2016-07-20 Pablo Kaluza , Masayo Inoue

We investigate the increasingly prominent task of jointly inferring multiple networks from nodal observations. While most joint inference methods assume that observations are available at all nodes, we consider the realistic and more…

Signal Processing · Electrical Eng. & Systems 2025-12-17 Madeline Navarro , Samuel Rey , Andrei Buciulea , Antonio G. Marques , Santiago Segarra

Networks of excitatory and inhibitory neurons display asynchronous irregular (AI) states, where the activities of the two populations are balanced. At the single cell level, it was shown that neurons subject to balanced and noisy synaptic…

Neurons and Cognition · Quantitative Biology 2016-11-29 Zahara Girones , Alain Destexhe

We address the questions of identifying pairs of interacting neurons from the observation of their spiking activity. The neuronal network is modeled by a system of interacting point processes with memory of variable length. The influence of…

Statistics Theory · Mathematics 2021-06-22 Emilio De Santis , Antonio Galves , Giovanna Nappo , Mauro Piccioni

Many biological neuronal networks exhibit highly variable spiking activity. Balanced networks offer a parsimonious model of this variability. In balanced networks, strong excitatory synaptic inputs are canceled by strong inhibitory inputs…

Neurons and Cognition · Quantitative Biology 2016-05-04 Ryan Pyle , Robert Rosenbaum

Networks of model neurons with balanced recurrent excitation and inhibition produce irregular and asynchronous spiking activity. We extend the analysis of balanced networks to include the known dependence of connection probability on the…

Neurons and Cognition · Quantitative Biology 2014-06-02 Robert Rosenbaum , Brent Doiron

This article is devoted to the theoretical and numerical analysis of a network of excitatory and inhibitory neurons of Hodgkin-Huxley (HH) type, for which the topology is inspired by that of a single local layer of visual cortex V1. Our…

Neurons and Cognition · Quantitative Biology 2021-08-13 M. Maama , B. Ambrosio , M. A. Aziz-Alaoui , S. M. Mintchev

To model biological systems using networks, it is desirable to allow more than two levels of expression for the nodes and to allow the introduction of parameters. Various modeling and simulation methods addressing these needs using Boolean…

Molecular Networks · Quantitative Biology 2014-04-23 Yi Ming Zou

Neural circuits often face the problem of classifying stimuli into discrete groups and making decisions based on such classifications. Neurons of these circuits can be distinguished according to their correlations with different features of…

Neurons and Cognition · Quantitative Biology 2007-05-23 Alexei A. Koulakov , Dmitry Rinberg , Dmitry N. Tsigankov

We show that a network of non-identical nodes, with excitable dynamics, pulse-coupled, with coupling delays depending on the Euclidean distance between nodes, is able to adapt the topology of its connections to obtain spike frequency…

Adaptation and Self-Organizing Systems · Physics 2023-03-27 L. Gil

Advances in neural recording methods enable sampling from populations of thousands of neurons during the performance of behavioral tasks, raising the question of how recorded activity relates to the theoretical models of computations…

Neurons and Cognition · Quantitative Biology 2020-07-01 Audrey J. Sederberg , Ilya Nemenman

A perturbative method is developed for calculating the effects of recurrent synaptic interactions between neurons embedded in a network. A series expansion is constructed that converges for networks with noisy membrane potential and weak…

Disordered Systems and Neural Networks · Physics 2009-11-10 Patrick D. Roberts

Models of biochemical networks are usually presented as connected graphs where vertices indicate proteins and edges are drawn to indicate activation or inhibition relationships. These diagrams are useful for drawing qualitative conclusions…

Dynamical Systems · Mathematics 2023-09-29 Chathranee Jayathilaka , Robyn Araujo , Lan Nguyen , Mark Flegg

We minimize a linear combination of the Willmore and the length functional among networks in $\mathbb{R}^d$ belonging to a given class determined by the number of curves, the order of the junctions and the angles between curves at the…

Optimization and Control · Mathematics 2021-09-30 Giacomo Del Nin , Alessandra Pluda , Marco Pozzetta

Neuropsychiatric disorders impact functional connectivity of the brain at the network level. The identification and statistical testing of disorder-related networks remains challenging. We propose novel methods to streamline the detection…

Applications · Statistics 2017-01-16 Shuo Chen , Yishi Xing , Jian Kang , Dinesh Shukla , Peter Kochunov , L. Elliot Hong

We initiate a line of investigation into biological neural networks from an algorithmic perspective. We develop a simplified but biologically plausible model for distributed computation in stochastic spiking neural networks and study…

Neural and Evolutionary Computing · Computer Science 2016-10-10 Nancy Lynch , Cameron Musco , Merav Parter

Identifiability of linear dynamic networks requires the presence of a sufficient number of external excitation signals. The problem of allocating a minimal number of external signals for guaranteeing generic network identifiability has been…

Systems and Control · Electrical Eng. & Systems 2022-05-16 H. J. Dreef , S. Shi , X. Cheng , M. C. F. Donkers , P. M. J. Van den Hof

This paper studies bifurcations in a three node power system when excitation limits are considered. This is done by approximating the limiter by a smooth function to facilitate bifurcation analysis. Spectacular qualitative changes in the…

Chaotic Dynamics · Physics 2007-05-23 Rajesh G. Kavasseri , K. R. Padiyar

We study the multistationarity for the reaction networks with one-dimensional stoichiometric subspaces, and we focus on the networks admitting finitely many positive steady states. We prove that if a network admits multistationarity, then…

Dynamical Systems · Mathematics 2021-08-24 Kexin Lin , Xiaoxian Tang , Zhishuo Zhang