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Diffusion models are a class of probabilistic generative models that have been widely used as a prior for image processing tasks like text conditional generation and inpainting. We demonstrate that these models can be adapted to make…

Machine Learning · Computer Science 2023-06-14 Marc Finzi , Anudhyan Boral , Andrew Gordon Wilson , Fei Sha , Leonardo Zepeda-Núñez

Phase-type distribution has been an important probabilistic tool in the analysis of complex stochastic system evolution. It was introduced by Neuts \cite{Neuts1975} in 1975. The model describes the lifetime distribution of a finite-state…

Methodology · Statistics 2016-11-14 B. A. Surya

We propose a unified framework that extends the inference methods for classical hidden Markov models to continuous settings, where both the hidden states and observations occur in continuous time. Two different settings are analyzed: hidden…

Methodology · Statistics 2021-06-18 Qingcan Wang , Weinan E

Structured distributions, i.e. distributions over combinatorial spaces, are commonly used to learn latent probabilistic representations from observed data. However, scaling these models is bottlenecked by the high computational and memory…

Computation and Language · Computer Science 2022-01-11 Justin T. Chiu , Yuntian Deng , Alexander M. Rush

We describe a continuous-time modelling framework for biological population dynamics that accounts for demographic noise. In the spirit of the methodology used by statistical physicists, transitions between the states of the system are…

Populations and Evolution · Quantitative Biology 2018-07-19 George W. A. Constable , Alan J. McKane

Time-delay systems are an important class of dynamical systems which provide a solid mathematical framework to deal with many application domains of interest ranging from biology, chemical, electrical, and mechanical engineering, to…

Dynamical Systems · Mathematics 2009-03-28 Giordano Pola , Pierdomenico Pepe , Maria D. Di Benedetto , Paulo Tabuada

In this paper we introduce a class of stochastic population models based on "patch dynamics". The size of the patch may be varied, and this allows one to quantify the departures of these stochastic models from various mean field theories,…

Populations and Evolution · Quantitative Biology 2009-11-11 A. J. McKane , T. J. Newman

Bayesian inference and the use of posterior or posterior predictive probabilities for decision making have become increasingly popular in clinical trials. The current practice in Bayesian clinical trials relies on a hybrid…

Methodology · Statistics 2024-04-30 Shirin Golchi , James Willard

We present a new method for inferring hidden Markov models from noisy time sequences without the necessity of assuming a model architecture, thus allowing for the detection of degenerate states. This is based on the statistical prediction…

Quantitative Methods · Quantitative Biology 2012-01-24 David Kelly , Mark Dillingham , Andrew Hudson , Karoline Wiesner

Statistical inference for discrete time observations of an affine stochastic delay differential equation is considered. The main focus is on maximum pseudo-likelihood estimators, which are easy to calculate in practice. A more general class…

Statistics Theory · Mathematics 2013-03-21 Uwe Küchler , Michael Sørensen

We explore the joint effect of the intrinsic noise and time delay on the spatial pattern formation within a multi-scale mobile lattice model of the epithelium. The protein fluctuations are driven by transcription/translation processes in…

Adaptation and Self-Organizing Systems · Physics 2015-06-12 Dmitry Bratsun , Andrey Zakharov

Density dependence is important in the ecology and evolution of microbial and cancer cells. Typically, we can only measure net growth rates, but the underlying density-dependent mechanisms that give rise to the observed dynamics can…

Populations and Evolution · Quantitative Biology 2025-06-04 Linh Huynh , Jacob G. Scott , Peter J. Thomas

This paper formed part of a preliminary research report for a risk consultancy and academic research. Stochastic Programming models provide a powerful paradigm for decision making under uncertainty. In these models the uncertainties are…

Computational Finance · Quantitative Finance 2009-04-08 Sovan Mitra

In the field of modeling the dynamics of oncolytic viruses, researchers often face the challenge of using specialized mathematical terms to explain uncertain biological phenomena. This paper introduces a basic framework for an oncolytic…

Dynamical Systems · Mathematics 2024-02-22 Zizi Wang

Anticipating and recognizing surgical workflows are critical for intelligent surgical assistance systems. However, existing methods rely on deterministic decision-making, struggling to generalize across the large anatomical and procedural…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Kaixiang Yang , Xin Li , Qiang Li , Zhiwei Wang

Time delay estimation plays a critical role in control, stabilization and state estimation of many practical system with time delay. In this paper, we propose a method to estimate delay for discrete time linear multiple-input…

Systems and Control · Electrical Eng. & Systems 2021-09-08 Iman Shafikhani , Hazhar Sufi Karimi , Mohammad Mohammadian , Amin Ramezani , Hamid Reza Momeni

Heterogeneities in environmental conditions often induce corresponding heterogeneities in the distribution of species. In the extreme case of a localized patch of increased growth rates, reproducing populations can become strongly…

Populations and Evolution · Quantitative Biology 2013-01-17 Lukas Geyrhofer , Oskar Hallatschek

Periodic patterns in dynamical behaviours of biological models described by simple form differential delay equations are studied. Mathematical models are given by a class of scalar delay differential equations with a multiplicative time…

Dynamical Systems · Mathematics 2025-10-01 A. Ivanov , S. Shelyag

We consider previous models of Timed, Probabilistic and Stochastic Timed Automata, we introduce our model of Timed Automata with Polynomial Delay and we characterize the expressiveness of these models relative to each other.

Logic in Computer Science · Computer Science 2019-03-19 Valentin Bura , Tim French , Mark Reynolds

In this note, we shall consider the existence of invariant measures for a class of infinite dimensional stochastic functional differential equations with delay whose driving semigroup is eventually norm continuous. The results obtained are…

Probability · Mathematics 2014-02-11 Kai Liu