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The integration of real-world data (RWD) and randomized controlled trials (RCT) is increasingly important for advancing causal inference in scientific research. This combination holds great promise for enhancing the efficiency of causal…

Methodology · Statistics 2024-07-02 Xi Lin , Jens Magelund Tarp , Robin J. Evans

Recently, a growing body of research has focused on either optimizing CTR model architectures to better model feature interactions or refining training objectives to aid parameter learning, thereby achieving better predictive performance.…

Machine Learning · Computer Science 2026-05-27 Moyu Zhang , Yun Chen , Yujun Jin , Jinxin Hu , Yu Zhang , Xiaoyi Zeng

We model, simulate and control the guiding problem for a herd of evaders under the action of repulsive drivers. The problem is formulated in an optimal control framework, where the drivers (controls) aim to guide the evaders (states) to a…

Optimization and Control · Mathematics 2020-05-01 Dongnam Ko , Enrique Zuazua

Model-Predictive Control (MPC) is a powerful tool for controlling complex, real-world systems that uses a model to make predictions about future behavior. For each state encountered, MPC solves an online optimization problem to choose a…

Machine Learning · Computer Science 2021-04-15 Mohak Bhardwaj , Sanjiban Choudhury , Byron Boots

Models trained on data composed of different groups or domains can suffer from severe performance degradation under distribution shifts. While recent methods have largely focused on optimizing the worst-group objective, this often comes at…

Machine Learning · Computer Science 2024-06-06 Hoang Phan , Andrew Gordon Wilson , Qi Lei

Developing artificial intelligence (AI) and machine learning (ML) models for medical imaging typically involves extensive training and testing on large datasets, consuming significant computational time, energy, and resources. There is a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Raj Hansini Khoiwal , Alan B. McMillan

This paper proposes a novel robust model predictive control (RMPC) method for the stabilization of constrained systems subject to additive disturbance (AD) and multiplicative disturbance (MD). Concentric containers are introduced to…

Systems and Control · Electrical Eng. & Systems 2024-12-05 Shibo Han , Yuhao Zhang , Xiaotong Shi , Xingwei Zhao

Pragmatic trials increasingly define outcomes using real-world data such as electronic health records, where assessments are collected during routine care rather than at fixed timepoints. Consequently, these uncontrolled assessments may be…

The primary outcome of Randomized clinical Trials (RCTs) are typically dichotomous, continuous, multivariate continuous, or time-to-event. However, what if this outcome is unstructured, e.g., a list of variables of mixed types, longitudinal…

Resin Transfer Molding (RTM), which has attracted much attention in the last years for lightweight manufacturing, represents an important challenge in terms of control technology. During the process, a resin fills the cavity where a…

Systems and Control · Electrical Eng. & Systems 2019-10-03 Miguel Escolano , Jose Manuel Rodriguez , Javier Orus , Manuel Laspalas , Agustin Chiminelli

Deep learning offers transformative potential in medical imaging, yet its clinical adoption is frequently hampered by challenges such as data scarcity, distribution shifts, and the need for robust task generalization. Prompt-based…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Hao Yang , Xinlong Liang , Zhang Li , Yue Sun , Zheyu Hu , Xinghe Xie , Behdad Dashtbozorg , Jincheng Huang , Shiwei Zhu , Luyi Han , Jiong Zhang , Shanshan Wang , Ritse Mann , Qifeng Yu , Tao Tan

Pruning can be an effective method of compressing large pre-trained models for inference speed acceleration. Previous pruning approaches rely on access to the original training dataset for both pruning and subsequent fine-tuning. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-11 Haihang Wu , Wei Wang , Tamasha Malepathirana , Sachith Seneviratne , Denny Oetomo , Saman Halgamuge

Remote Sensing Change Detection (RS-CD) aims to detect relevant changes from Multi-Temporal Remote Sensing Images (MT-RSIs), which aids in various RS applications such as land cover, land use, human development analysis, and disaster…

Computer Vision and Pattern Recognition · Computer Science 2023-03-17 Wele Gedara Chaminda Bandara , Vishal M. Patel

Real-world clinical data is inherently multimodal, providing complementary evidence that mirrors the practical necessity of jointly assessing multiple related outcomes. Although multi-task learning can improve efficiency by sharing…

Machine Learning · Computer Science 2026-05-06 He Lyu , Huolin Zeng , Junren Wang , Huazhen Yang , Linchao He , Yong Chen , Zhirui Li , Andreas Maier , Siming Bayer , Huan Song

Randomized Controlled Trials (RCT)s are relied upon to assess new treatments, but suffer from limited power to guide personalized treatment decisions. On the other hand, observational (i.e., non-experimental) studies have large and diverse…

Methodology · Statistics 2023-03-07 Zeshan Hussain , Ming-Chieh Shih , Michael Oberst , Ilker Demirel , David Sontag

In model-predictive control (MPC), achieving the best closed-loop performance under a given computational resource is the underlying design consideration. This paper analyzes the MPC design problem with control performance and required…

Optimization and Control · Mathematics 2016-04-25 Vincent Bachtiar , Chris Manzie , William H. Moase , Eric C. Kerrigan

Accurate estimation of treatment effects in online A/B testing is challenging with zero-inflated and skewed metrics. Traditional tests, like Welch's t-test, often lack sensitivity with heavy-tailed data due to their reliance on means, as…

Methodology · Statistics 2025-10-07 Kevin Charette , Tristan Boudreault

With recent achievements in tasks requiring context awareness, foundation models have been adopted to treat large-scale data from electronic health record (EHR) systems. However, previous clinical recommender systems based on foundation…

Artificial Intelligence · Computer Science 2023-02-02 Seunghyun Lee , Da Young Lee , Sujeong Im , Nan Hee Kim , Sung-Min Park

There has been an increasing use of master protocols in oncology clinical trials because of its efficiency and flexibility to accelerate cancer drug development. Depending on the study objective and design, a master protocol trial can be a…

Applications · Statistics 2023-11-13 Jie Chen , Xiaoyun , Li , Chengxing , Lu , Sammy Yuan , Godwin Yung , Jingjing Ye , Hong Tian , Jianchang Lin

When designing control strategies for differential-drive mobile robots, one standard tool is the consideration of a point at a fixed distance along a line orthogonal to the wheel axis instead of the full pose of the vehicle. This…

Robotics · Computer Science 2018-02-21 Paul Glotfelter , Magnus Egerstedt