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Depression poses significant challenges to patients and healthcare organizations, necessitating efficient assessment methods. Existing paradigms typically focus on a patient-doctor way that overlooks multi-role interactions, such as family…

Human-Computer Interaction · Computer Science 2026-03-10 Zhiyuan Zhou , Jilong Liu , Sanwang Wang , Shijie Hao , Yanrong Guo , Richang Hong

Personalized recommendation requires models that capture sequential user preferences while remaining robust to sparse feedback and semantic ambiguity. Recent work has explored large language models (LLMs) as recommenders and re-rankers, but…

Information Retrieval · Computer Science 2026-04-22 Siqi Liang , Xiawei Wang , Yudi Zhang , Jiaying Zhou

Benefiting from the powerful expressive capability of graphs, graph-based approaches have achieved impressive performance in various biomedical applications. Most existing methods tend to define the adjacency matrix among samples manually…

Machine Learning · Computer Science 2021-07-02 Shuai Zheng , Zhenfeng Zhu , Zhizhe Liu , Zhenyu Guo , Yang Liu , Yao Zhao

Recommender systems (RSs) are designed to retrieve candidate items a user might be interested in from a large pool. A common approach is using graph neural networks (GNNs) to capture high-order interaction relationships. As large language…

Information Retrieval · Computer Science 2025-06-24 Junze Chen , Xinjie Yang , Cheng Yang , Junfei Bao , Zeyuan Guo , Yawen Li , Chuan Shi

Retrieval-augmented generation (RAG) has rapidly emerged as a transformative approach for integrating large language models into clinical and biomedical workflows. However, privacy risks, such as protected health information (PHI) exposure,…

Cryptography and Security · Computer Science 2025-11-18 Shaowei Guan , Hin Chi Kwok , Ngai Fong Law , Gregor Stiglic , Harry Qin , Vivian Hui

Digital health analytics face critical challenges nowadays. The sophisticated analysis of patient-generated health content, which contains complex emotional and medical contexts, requires scarce domain expertise, while traditional ML…

We propose a novel framework for integrating fragmented multi-modal data in Alzheimer's disease (AD) research using large language models (LLMs) and knowledge graphs. While traditional multimodal analysis requires matched patient IDs across…

Machine Learning · Computer Science 2025-08-19 Kanan Kiguchi , Yunhao Tu , Katsuhiro Ajito , Fady Alnajjar , Kazuyuki Murase

Large language models (LLMs) are revolutionizing the field of education by enabling personalized learning experiences tailored to individual student needs. In this paper, we introduce a framework for Adaptive Learning Systems that leverages…

Computers and Society · Computer Science 2025-07-28 Yongjie Li , Ruilin Nong , Jianan Liu , Lucas Evans

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

The field of healthcare has increasingly turned its focus towards Large Language Models (LLMs) due to their remarkable performance. However, their performance in actual clinical applications has been underexplored. Traditional evaluations…

Large language models (LLMs) increasingly serve as the central control unit of AI agents, yet current approaches remain limited in their ability to deliver personalized interactions. While Retrieval Augmented Generation enhances LLM…

Artificial Intelligence · Computer Science 2025-10-10 Rebecca Westhäußer , Wolfgang Minker , Sebatian Zepf

Large language models (LLMs) used in medical applications are known to be prone to exhibiting biased and unfair patterns. Prior to deploying these in clinical decision-making, it is crucial to identify such bias patterns to enable effective…

Artificial Intelligence · Computer Science 2025-12-23 Farzana Islam Adiba , Rahmatollah Beheshti

Mental health issues significantly impact individuals' daily lives, yet many do not receive the help they need even with available online resources. This study aims to provide diverse, accessible, stigma-free, personalized, and real-time…

Computation and Language · Computer Science 2025-09-23 Qiming Guo , Jinwen Tang , Wenbo Sun , Haoteng Tang , Yi Shang , Wenlu Wang

Data augmentation is necessary for graph representation learning due to the scarcity and noise present in graph data. Most of the existing augmentation methods overlook the context information inherited from the dataset as they rely solely…

Machine Learning · Computer Science 2025-02-20 Yushi Feng , Tsai Hor Chan , Guosheng Yin , Lequan Yu

Clinical case formulation organizes patient symptoms and psychosocial factors into causal models, often using the 5P framework. However, constructing such graphs from therapy transcripts is time consuming and varies across clinicians. We…

Computation and Language · Computer Science 2026-04-15 Shreya Gupta , Prottay Kumar Adhikary , Bhavyaa Dave , Salam Michael Singh , Aniket Deroy , Tanmoy Chakraborty

The advancement of Large Language Models (LLMs) has remarkably pushed the boundaries towards artificial general intelligence (AGI), with their exceptional ability on understanding diverse types of information, including but not limited to…

Computation and Language · Computer Science 2023-10-10 Ziwei Chai , Tianjie Zhang , Liang Wu , Kaiqiao Han , Xiaohai Hu , Xuanwen Huang , Yang Yang

Large Language Models (LLMs) have garnered considerable interest within both academic and industrial. Yet, the application of LLMs to graph data remains under-explored. In this study, we evaluate the capabilities of four LLMs in addressing…

Artificial Intelligence · Computer Science 2023-09-12 Chang Liu , Bo Wu

The rise of Generative AI, and Large Language Models (LLMs) in particular, is fundamentally changing cognitive processes in knowledge work, raising critical questions about their impact on human reasoning and problem-solving capabilities.…

Human-Computer Interaction · Computer Science 2025-04-04 Joshua Holstein , Moritz Diener , Philipp Spitzer

The advent of Large Language Models (LLMs) has ushered in a new era for design science in Information Systems, demanding a paradigm shift in tailoring LLMs design for business contexts. We propose and test a novel framework to customize…

Computers and Society · Computer Science 2024-05-15 Wen Wang , Zhenyue Zhao , Tianshu Sun

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta