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Deep learning models have exhibited exceptional effectiveness in Computational Pathology (CPath) by tackling intricate tasks across an array of histology image analysis applications. Nevertheless, the presence of out-of-distribution data…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 Mostafa Jahanifar , Manahil Raza , Kesi Xu , Trinh Vuong , Rob Jewsbury , Adam Shephard , Neda Zamanitajeddin , Jin Tae Kwak , Shan E Ahmed Raza , Fayyaz Minhas , Nasir Rajpoot

Purpose: To develop an algorithm for the retrospective correction of signal dropout artifacts in abdominal diffusion-weighted imaging (DWI) resulting from cardiac motion. Methods: Given a set of image repetitions for a slice, a locally…

Image and Video Processing · Electrical Eng. & Systems 2022-02-22 Fasil Gadjimuradov , Thomas Benkert , Marcel Dominik Nickel , Tobit Führes , Marc Saake , Andreas Maier

Despite notable advancements, the integration of deep learning (DL) techniques into impactful clinical applications, particularly in the realm of digital histopathology, has been hindered by challenges associated with achieving robust…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Sebastian Doerrich , Francesco Di Salvo , Christian Ledig

Standard neural networks struggle to generalize under distribution shifts in computer vision. Fortunately, combining multiple networks can consistently improve out-of-distribution generalization. In particular, weight averaging (WA)…

Computer Vision and Pattern Recognition · Computer Science 2023-01-30 Alexandre Ramé , Matthieu Kirchmeyer , Thibaud Rahier , Alain Rakotomamonjy , Patrick Gallinari , Matthieu Cord

Domain shift is a significant problem in histopathology. There can be large differences in data characteristics of whole-slide images between medical centers and scanners, making generalization of deep learning to unseen data difficult. To…

Computer Vision and Pattern Recognition · Computer Science 2019-09-27 Karin Stacke , Gabriel Eilertsen , Jonas Unger , Claes Lundström

Deep learning models have shown immense promise in computational pathology (CPath) tasks, but their performance often suffers when applied to unseen data due to domain shifts. Addressing this requires domain generalization (DG) algorithms.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Neda Zamanitajeddin , Mostafa Jahanifar , Kesi Xu , Fouzia Siraj , Nasir Rajpoot

Histopathological images are essential for medical diagnosis and treatment planning, but interpreting them accurately using machine learning can be challenging due to variations in tissue preparation, staining and imaging protocols. Domain…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Vaibhav Khamankar , Sutanu Bera , Saumik Bhattacharya , Debashis Sen , Prabir Kumar Biswas

In a variational denoising model, weight in the data fidelity term plays the role of enhancing the noise-removal capability. It is profoundly correlated with noise information, while also balancing the data fidelity and regularization…

Image and Video Processing · Electrical Eng. & Systems 2026-04-14 Xiangyu Rui , Xiangyong Cao , Xile Zhao , Deyu Meng , Michael K. NG

Despite the simplicity, stochastic gradient descent (SGD)-like algorithms are successful in training deep neural networks (DNNs). Among various attempts to improve SGD, weight averaging (WA), which averages the weights of multiple models,…

Machine Learning · Computer Science 2023-04-25 Xiaozhe Gu , Zixun Zhang , Yuncheng Jiang , Tao Luo , Ruimao Zhang , Shuguang Cui , Zhen Li

The process of digitising histology slides involves multiple factors that can affect a whole slide image's (WSI) final appearance, including the staining protocol, scanner, and tissue type. This variability constitutes a domain shift and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Manahil Raza , Saad Bashir , Talha Qaiser , Nasir Rajpoot

Weight averaging is a widely used technique for accelerating training and improving the generalization of deep neural networks (DNNs). While existing approaches like stochastic weight averaging (SWA) rely on pre-set weighting schemes, they…

Machine Learning · Computer Science 2025-02-11 Tao Li , Zhehao Huang , Yingwen Wu , Zhengbao He , Qinghua Tao , Xiaolin Huang , Chih-Jen Lin

In this paper, we address domain shifts in pathological images by focusing on shifts within whole slide images~(WSIs), such as patient characteristics and tissue thickness, rather than shifts between hospitals. Traditional approaches rely…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Yuki Shigeyasu , Shota Harada , Akihiko Yoshizawa , Kazuhiro Terada , Naoki Nakazima , Mariyo Kurata , Hiroyuki Abe , Tetsuo Ushiku , Ryoma Bise

Diagnostic imaging has gained prominence as potential biomarkers for early detection and diagnosis in a diverse array of disorders including cancer. However, existing methods routinely face challenges arising from various factors such as…

End-to-end deep learning improves breast cancer classification on diffusion-weighted MR images (DWI) using a convolutional neural network (CNN) architecture. A limitation of CNN as opposed to previous model-based approaches is the…

Preparing and scanning histopathology slides consists of several steps, each with a multitude of parameters. The parameters can vary between pathology labs and within the same lab over time, resulting in significant variability of the…

Computer Vision and Pattern Recognition · Computer Science 2018-01-11 Maxime W. Lafarge , Josien P. W. Pluim , Koen A. J. Eppenhof , Pim Moeskops , Mitko Veta

In this paper, we propose a new method called Self-Training with Dynamic Weighting (STDW), which aims to enhance robustness in Gradual Domain Adaptation (GDA) by addressing the challenge of smooth knowledge migration from the source to the…

Machine Learning · Computer Science 2025-10-17 Zixi Wang , Yushe Cao , Yubo Huang , Jinzhu Wei , Jingzehua Xu , Shuai Zhang , Xin Lai

The development of robust artificial intelligence models for histopathology diagnosis is severely constrained by the scarcity of expert-annotated lesion data, particularly for rare pathologies and underrepresented disease subtypes. While…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Mohamad Koohi-Moghadam , Mohammad-Ali Nikouei Mahani , Kyongtae Tyler Bae

Histopathology is a reflection of the molecular changes and provides prognostic phenotypes representing the disease progression. In this study, we introduced feature scores generated from hematoxylin and eosin histology images based on deep…

Quantitative Methods · Quantitative Biology 2020-07-28 Okyaz Eminaga , Mahmood Abbas , Yuri Tolkach , Rosalie Nolley , Christian Kunder , Axel Semjonow , Martin Boegemann

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

Computer Vision and Pattern Recognition · Computer Science 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh

Medical image analysis (MedIA) has become an essential tool in medicine and healthcare, aiding in disease diagnosis, prognosis, and treatment planning, and recent successes in deep learning (DL) have made significant contributions to its…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Jee Seok Yoon , Kwanseok Oh , Yooseung Shin , Maciej A. Mazurowski , Heung-Il Suk
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