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We introduce ReaMIL (Reasoning- and Evidence-Aware MIL), a multiple instance learning approach for whole-slide histopathology that adds a light selection head to a strong MIL backbone. The head produces soft per-tile gates and is trained…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Hyun Do Jung , Jungwon Choi , Hwiyoung Kim

For classifying digital whole slide images in the absence of pixel level annotation, typically multiple instance learning methods are applied. Due to the generic applicability, such methods are currently of very high interest in the…

The EM algorithm is a method for finding the maximum likelihood estimate of a model in the presence of missing data. Unfortunately, EM does not produce a parameter covariance matrix for standard errors. Supplemented EM (SEM; Meng & Rubin,…

Computation · Statistics 2016-05-04 Joshua N. Pritikin

Large language models have shown remarkable performance across a wide range of language tasks, owing to their exceptional capabilities in context modeling. The most commonly used method of context modeling is full self-attention, as seen in…

Computation and Language · Computer Science 2025-06-26 Zhisong Zhang , Yan Wang , Xinting Huang , Tianqing Fang , Hongming Zhang , Chenlong Deng , Shuaiyi Li , Dong Yu

Mixup is an effective data augmentation method that generates new augmented samples by aggregating linear combinations of different original samples. However, if there are noises or aberrant features in the original samples, Mixup may…

Machine Learning · Computer Science 2024-05-09 Leixin Yang , Yu Xiang

In digital pathology, Whole Slide Image (WSI) analysis is usually formulated as a Multiple Instance Learning (MIL) problem. Although transformer-based architectures have been used for WSI classification, these methods require modifications…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Juan I. Pisula , Katarzyna Bozek

Deep networks achieve excellent results on large-scale clean data but degrade significantly when learning from noisy labels. To suppressing the impact of mislabeled data, this paper proposes a conceptually simple yet efficient training…

Computer Vision and Pattern Recognition · Computer Science 2020-10-30 Xiaojiang Peng , Kai Wang , Zhaoyang Zeng , Qing Li , Jianfei Yang , Yu Qiao

We point out a limitation of the mutual information neural estimation (MINE) where the network fails to learn at the initial training phase, leading to slow convergence in the number of training iterations. To solve this problem, we propose…

Information Theory · Computer Science 2019-06-03 Chung Chan , Ali Al-Bashabsheh , Hing Pang Huang , Michael Lim , Da Sun Handason Tam , Chao Zhao

Multiple Instance Learning is the predominant method for Whole Slide Image classification in digital pathology, enabling the use of slide-level labels to supervise model training. Although MIL eliminates the tedious fine-grained annotation…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Chen Shu , Boyu Fu , Yiman Li , Ting Yin , Wenchuan Zhang , Jie Chen , Yuhao Yi , Hong Bu

Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised classification in whole slide image (WSI) based pathology diagnosis. However, the current MIL methods are usually based on independent and identical…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Zhuchen Shao , Hao Bian , Yang Chen , Yifeng Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

Attention is a vital cognitive process in the learning and memory environment, particularly in the context of online learning. Traditional methods for classifying attention states of online learners based on behavioral signals are prone to…

Human-Computer Interaction · Computer Science 2025-01-10 Huan Liu , Yuzhe Zhang , Guanjian Liu , Xinxin Du , Haochong Wang , Dalin Zhang

Whole Slide Images (WSIs) present a challenging computer vision task due to their gigapixel size and presence of numerous artefacts. Yet they are a valuable resource for patient diagnosis and stratification, often representing the gold…

Computer Vision and Pattern Recognition · Computer Science 2023-10-05 Amaya Gallagher-Syed , Luca Rossi , Felice Rivellese , Costantino Pitzalis , Myles Lewis , Michael Barnes , Gregory Slabaugh

Whole slide image (WSI) classification is a critical task in computational pathology, requiring the processing of gigapixel-sized images, which is challenging for current deep-learning methods. Current state of the art methods are based on…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Jingwei Zhang , Saarthak Kapse , Ke Ma , Prateek Prasanna , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

The Maximum Entropy Method (MEM) is a popular data analysis technique based on Bayesian inference, which has found various applications in the research literature. While the MEM itself is well-grounded in statistics, I argue that its…

Data Analysis, Statistics and Probability · Physics 2020-11-03 Alexander Rothkopf

Instruction tuning is essential for aligning large language models (LLMs) to downstream tasks and commonly relies on large, diverse corpora. However, small, high-quality subsets, known as coresets, can deliver comparable or superior…

Computation and Language · Computer Science 2026-05-15 Manish Nagaraj , Sakshi Choudhary , Utkarsh Saxena , Deepak Ravikumar , Kaushik Roy

Automatic image annotation (AIA) raises tremendous challenges to machine learning as it requires modeling of data that are both ambiguous in input and output, e.g., images containing multiple objects and labeled with multiple semantic tags.…

Machine Learning · Computer Science 2012-03-19 Shuang Hong Yang , Jiang Bian , Hongyuan Zha

Missing data is a recurrent and challenging problem, especially when using machine learning algorithms for real-world applications. For this reason, missing data imputation has become an active research area, in which recent deep learning…

Machine Learning · Computer Science 2021-07-01 Simon Tihon , Muhammad Usama Javaid , Damien Fourure , Nicolas Posocco , Thomas Peel

Detecting anomalies over real-world datasets remains a challenging task. Data annotation is an intensive human labor problem, particularly in sequential datasets, where the start and end time of anomalies are not known. As a result, data…

Machine Learning · Computer Science 2022-10-05 Parastoo Kamranfar , David Lattanzi , Amarda Shehu , Daniel Barbará

The recent surge of large language models (LLMs) highlights their ability to perform in-context learning, i.e., "learning" to perform a task from a few demonstrations in the context without any parameter updates. However, their capabilities…

Computation and Language · Computer Science 2023-07-07 Tianle Cai , Kaixuan Huang , Jason D. Lee , Mengdi Wang

Surveillance videos are able to capture a variety of realistic anomalies. In this paper, we propose to learn anomalies by exploiting both normal and anomalous videos. To avoid annotating the anomalous segments or clips in training videos,…

Computer Vision and Pattern Recognition · Computer Science 2019-02-15 Waqas Sultani , Chen Chen , Mubarak Shah