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Dynamic computed tomography perfusion (CTP) imaging is a promising approach for acute ischemic stroke diagnosis and evaluation. Hemodynamic parametric maps of cerebral parenchyma are calculated from repeated CT scans of the first pass of…

Background: Limited-angle (LA) dual-energy (DE) cone-beam CT (CBCT) is considered as a potential solution to achieve fast and low-dose DE imaging on current CBCT scanners without hardware modification. However, its clinical implementations…

Person image generation aims to perform non-rigid deformation on source images, which generally requires unaligned data pairs for training. Recently, self-supervised methods express great prospects in this task by merging the disentangled…

In cluster-randomized trials (CRTs), entire clusters of individuals are randomized to treatment, and outcomes within a cluster are typically correlated. While frequentist approaches are standard practice for CRT analysis, Bayesian methods…

Current deep neural network based approaches to computed tomography (CT) metal artifact reduction (MAR) are supervised methods which rely heavily on synthesized data for training. However, as synthesized data may not perfectly simulate the…

Traditional model-based image reconstruction (MBIR) methods combine forward and noise models with simple object priors. Recent machine learning methods for image reconstruction typically involve supervised learning or unsupervised learning,…

Convolutional neural network (CNN) has achieved unprecedented success in image super-resolution tasks in recent years. However, the network's performance depends on the distribution of the training sets and degrades on out-of-distribution…

Automated lesion segmentation from computed tomography (CT) is an important and challenging task in medical image analysis. While many advancements have been made, there is room for continued improvements. One hurdle is that CT images can…

Self-supervised instance discrimination is an effective contrastive pretext task to learn feature representations and address limited medical image annotations. The idea is to make features of transformed versions of the same images similar…

Computed Tomography (CT) is widely used in healthcare for detailed imaging. However, Low-dose CT, despite reducing radiation exposure, often results in images with compromised quality due to increased noise. Traditional methods, including…

Pre-training general-purpose visual features with convolutional neural networks without relying on annotations is a challenging and important task. Most recent efforts in unsupervised feature learning have focused on either small or highly…

Cone-beam CT (CBCT) provides on-board volumetric anatomy for image guidance and treatment adaptation in radiotherapy. To compensate for respiration-induced anatomical motion, time-resolved CBCT is highly desired to capture the…

Purpose: To evaluate a proposed method to reconstruct CT numbers that accurately mimic conventional CT numbers from spectral CT data, as would have been produced by a conventional system without effects of beam hardening. Approach: We…

Computed Tomography (CT) is a medical imaging modality that can generate more informative 3D images than 2D X-rays. However, this advantage comes at the expense of more radiation exposure, higher costs, and longer acquisition time. Hence,…

Biomedical image segmentation plays a significant role in computer-aided diagnosis. However, existing CNN based methods rely heavily on massive manual annotations, which are very expensive and require huge human resources. In this work, we…

Spectral computed tomography (CT) is an emerging technology capable of providing high chemical specificity, which is crucial for many applications such as detecting threats in luggage. This type of application requires both fast and…

Computed tomography (CT) involves a patient's exposure to ionizing radiation. To reduce the radiation dose, we can either lower the X-ray photon count or down-sample projection views. However, either of the ways often compromises image…

Cardiac Magnetic Resonance (CMR) imaging is a vital non-invasive tool for diagnosing heart diseases and evaluating cardiac health. However, the limited availability of large-scale, high-quality CMR datasets poses a major challenge to the…

The generative priors of pre-trained latent diffusion models (DMs) have demonstrated great potential to enhance the visual quality of image super-resolution (SR) results. However, the noise sampling process in DMs introduces randomness in…

Purpose: Coronary artery calcium (CAC) score, i.e. the amount of CAC quantified in CT, is a strong and independent predictor of coronary heart disease (CHD) events. However, CAC scoring suffers from limited interscan reproducibility, which…