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Due to its wide field of view, cone-beam computed tomography (CBCT) is plagued by large amounts of scatter, where attenuated photons hit the detector, and corrupt the linear models used for reconstruction. Given that one can generate a good…

Medical Physics · Physics 2017-07-06 Jonathan Mason , Alessandro Perelli , William Nailon , Mike Davies

Image-generative artificial intelligence (AI) has garnered significant attention in recent years. In particular, the diffusion model, a core component of generative AI, produces high-quality images with rich diversity. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Sho Ozaki , Shizuo Kaji , Toshikazu Imae , Kanabu Nawa , Hideomi Yamashita , Keiichi Nakagawa

Cone beam computed tomography (CBCT) is an emerging medical imaging technique to visualize the internal anatomical structures of patients. During a CBCT scan, several projection images of different angles or views are collectively utilized…

Image and Video Processing · Electrical Eng. & Systems 2024-01-18 Heejun Shin , Taehee Kim , Jongho Lee , Se Young Chun , Seungryung Cho , Dongmyung Shin

Contrast-enhanced computed tomography (CT) imaging is essential for diagnosing and monitoring thoracic diseases, including aortic pathologies. However, contrast agents pose risks such as nephrotoxicity and allergic-like reactions. The…

Image and Video Processing · Electrical Eng. & Systems 2025-09-08 Pouya Shiri , Xin Yi , Neel P. Mistry , Samaneh Javadinia , Mohammad Chegini , Seok-Bum Ko , Amirali Baniasadi , Scott J. Adams

Image synthesis is used to generate synthetic CTs (sCTs) from on-treatment cone-beam CTs (CBCTs) with a view to improving image quality and enabling accurate dose computation to facilitate a CBCT-based adaptive radiotherapy workflow. As…

Image and Video Processing · Electrical Eng. & Systems 2023-12-05 Chelsea A. H. Sargeant , Edward G. A. Henderson , Dónal M. McSweeney , Aaron G. Rankin , Denis Page

Supervised synthetic CT generation from CBCT requires registered training pairs, yet perfect registration between separately acquired scans remains unattainable. This registration bias propagates into trained models and corrupts standard…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lukas Zimmermann , Michael Rauter , Maximilian Schmid , Dietmar Georg , Barbara Knäusl

The radiation dose in computed tomography (CT) examinations is harmful for patients but can be significantly reduced by intuitively decreasing the number of projection views. Reducing projection views usually leads to severe aliasing…

Image and Video Processing · Electrical Eng. & Systems 2022-11-28 Bing Guan , Cailian Yang , Liu Zhang , Shanzhou Niu , Minghui Zhang , Yuhao Wang , Weiwen Wu , Qiegen Liu

Scatter can account for large errors in cone-beam CT (CBCT) due to its wide field of view, and its complicated nature makes its compensation difficult. Iterative polyenergetic reconstruction algorithms offer the potential to provide…

Medical Physics · Physics 2020-01-13 Jonathan H. Mason , Alessandro Perelli , William H. Nailon , Mike E. Davies

Pancreatic cancer with more than 60,000 new cases each year has less than 10 percent 5-year overall survival. Radiation therapy (RT) is an effective treatment for Locally advanced pancreatic cancer (LAPC). The current clinical RT workflow…

Medical Physics · Physics 2023-06-07 Hamed Hooshangnejad , Quan Chen , Xue Feng , Rui Zhang , Kai Ding

Building accurate and robust artificial intelligence systems for medical image assessment requires not only the research and design of advanced deep learning models but also the creation of large and curated sets of annotated training…

Computer Vision and Pattern Recognition · Computer Science 2022-01-05 Florin C. Ghesu , Bogdan Georgescu , Awais Mansoor , Youngjin Yoo , Dominik Neumann , Pragneshkumar Patel , R. S. Vishwanath , James M. Balter , Yue Cao , Sasa Grbic , Dorin Comaniciu

Cone-beam computed tomography (CBCT) is a popular imaging modality in dentistry for diagnosing and planning treatment for a variety of oral diseases with the ability to produce detailed, three-dimensional images of the teeth, jawbones, and…

Image and Video Processing · Electrical Eng. & Systems 2023-06-08 Saba Sarwar , Suraiya Jabin

Existing medical image super-resolution methods rely on pairs of low- and high- resolution images to learn a mapping in a fully supervised manner. However, such image pairs are often not available in clinical practice. In this paper, we…

Image and Video Processing · Electrical Eng. & Systems 2021-02-08 Hongwei Li , Rameshwara G. N. Prasad , Anjany Sekuboyina , Chen Niu , Siwei Bai , Werner Hemmert , Bjoern Menze

Computed tomography (CT) has been developed as a non-destructive technique for observing minute internal images of samples. It has been difficult to obtain photo-realistic (clean or clear) CT images due to various unwanted artifacts…

Quantum Physics · Physics 2023-09-12 Kyungtaek Jun

In dental cone-beam computed tomography (CBCT), compact and cost-effective system designs often use small detectors, resulting in a truncated field of view (FOV) that does not fully encompass the patient's head. In iterative reconstruction…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Hyoung Suk Park , Kiwan Jeon

Positron Emission Tomography (PET) imaging requires accurate attenuation correction (AC) to account for photon loss due to tissue density variations. In PET/MR systems, computed tomography (CT), which offers a straightforward estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Weijie Chen , James Wang , Alan McMillan

Deep learning has shown impressive results in reducing noise and artifacts in X-ray computed tomography (CT) reconstruction. Self-supervised CT reconstruction methods are especially appealing for real-world applications because they require…

Image and Video Processing · Electrical Eng. & Systems 2026-05-06 Dirk Elias Schut , Adriaan Graas , Robert van Liere , Tristan van Leeuwen

Computed tomography (CT) serves as an effective tool for lung cancer screening, diagnosis, treatment, and prognosis, providing a rich source of features to quantify temporal and spatial tumor changes. Nonetheless, the diversity of CT…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Md Selim , Jie Zhang , Faraneh Fathi , Michael A. Brooks , Ge Wang , Guoqiang Yu , Jin Chen

This paper proposes a novel, unsupervised super-resolution (SR) approach for performing the SR of a clinical CT into the resolution level of a micro CT ($\mu$CT). The precise non-invasive diagnosis of lung cancer typically utilizes clinical…

Image and Video Processing · Electrical Eng. & Systems 2020-11-22 Tong Zheng , Hirohisa Oda , Masahiro Oda , Shota Nakamura , Masaki Mori , Hirotsugu Takabatake , Hiroshi Natori , Kensaku Mori

Background: Dual-energy imaging on cone-beam CT (CBCT) scanners has great potential in different clinical applications, including image-guided surgery and adaptive proton therapy. However, the clinical practice of dual-energy CBCT (DE-CBCT)…

Transcranial MRI-guided focused ultrasound (TcMRgFUS) is a therapeutic ultrasound method that focuses sound through the skull to a small region noninvasively under MRI guidance. It is clinically approved to thermally ablate regions of the…

Computer Vision and Pattern Recognition · Computer Science 2022-02-23 Han Liu , Michelle K. Sigona , Thomas J. Manuel , Li Min Chen , Charles F. Caskey , Benoit M. Dawant