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The recent development of data-driven AI promises to automate medical diagnosis; however, most AI functions as 'black boxes' to physicians with limited computational knowledge. Using medical imaging as a point of departure, we conducted…

Human-Computer Interaction · Computer Science 2020-01-22 Yao Xie , Melody Chen , David Kao , Ge Gao , Xiang 'Anthony' Chen

Generative models are capable of producing human-expert level content across a variety of topics and domains. As the impact of generative models grows, it is necessary to develop statistical methods to understand collections of available…

Machine Learning · Computer Science 2025-05-23 Hayden Helm , Aranyak Acharyya , Brandon Duderstadt , Youngser Park , Carey E. Priebe

Progress in image generation raises significant public security concerns. We argue that fake image detection should not operate as a "black box". Instead, an ideal approach must ensure both strong generalization and transparency. Recent…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Yikun Ji , Yan Hong , Jiahui Zhan , Haoxing Chen , jun lan , Huijia Zhu , Weiqiang Wang , Liqing Zhang , Jianfu Zhang

Deep learning has the potential to automate many clinically useful tasks in medical imaging. However translation of deep learning into clinical practice has been hindered by issues such as lack of the transparency and interpretability in…

Image and Video Processing · Electrical Eng. & Systems 2022-05-04 Charles Lu , Andreanne Lemay , Ken Chang , Katharina Hoebel , Jayashree Kalpathy-Cramer

Researches have shown that deep neural networks are vulnerable to malicious attacks, where adversarial images are created to trick a network into misclassification even if the images may give rise to totally different labels by human eyes.…

Computer Vision and Pattern Recognition · Computer Science 2022-05-11 Yuzhen Ding , Nupur Thakur , Baoxin Li

Artificial intelligence, particularly through recent advancements in deep learning, has achieved exceptional performances in many tasks in fields such as natural language processing and computer vision. In addition to desirable evaluation…

Machine Learning · Computer Science 2024-03-04 Sean Xie , Soroush Vosoughi , Saeed Hassanpour

The unprecedented performance of machine learning models in recent years, particularly Deep Learning and transformer models, has resulted in their application in various domains such as finance, healthcare, and education. However, the…

Human-Computer Interaction · Computer Science 2023-12-20 Milad Rogha

In many practical applications, deep neural networks have been typically deployed to operate as a black box predictor. Despite the high amount of work on interpretability and high demand on the reliability of these systems, they typically…

Artificial Intelligence · Computer Science 2020-12-07 Martin Stano , Wanda Benesova , Lukas Samuel Martak

As the field of healthcare increasingly adopts artificial intelligence, it becomes important to understand which types of explanations increase transparency and empower users to develop confidence and trust in the predictions made by…

Artificial Intelligence · Computer Science 2025-05-16 Felix Liedeker , Olivia Sanchez-Graillet , Moana Seidler , Christian Brandt , Jörg Wellmer , Philipp Cimiano

AI-enhanced personality assessments are increasingly shaping hiring decisions, using affective computing to predict traits from the Big Five (OCEAN) model. However, integrating AI into these assessments raises ethical concerns, especially…

Human-Computer Interaction · Computer Science 2025-11-24 Dena F. Mujtaba , Nihar R. Mahapatra

Explainability for machine learning models has gained considerable attention within the research community given the importance of deploying more reliable machine-learning systems. In computer vision applications, generative counterfactual…

Machine Learning · Computer Science 2021-11-12 Pau Rodriguez , Massimo Caccia , Alexandre Lacoste , Lee Zamparo , Issam Laradji , Laurent Charlin , David Vazquez

Counterfactual explanations enhance the interpretability of deep learning models in medical imaging, yet adapting them to 3D CT scans poses challenges due to volumetric complexity and resource demands. We extend the Latent Shift…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Joseph Paul Cohen , Louis Blankemeier , Akshay Chaudhari

The advent of black-box deep neural network classification models has sparked the need to explain their decisions. However, in the case of generative AI, such as large language models (LLMs), there is no class prediction to explain. Rather,…

Computation and Language · Computer Science 2025-02-18 Ronny Luss , Erik Miehling , Amit Dhurandhar

The misuse of AI imagery can have harmful societal effects, prompting the creation of detectors to combat issues like the spread of fake news. Existing methods can effectively detect images generated by seen generators, but it is…

Computer Vision and Pattern Recognition · Computer Science 2023-12-15 Mingjian Zhu , Hanting Chen , Mouxiao Huang , Wei Li , Hailin Hu , Jie Hu , Yunhe Wang

The growing integration of machine learning (ML) and artificial intelligence (AI) models into high-stakes domains such as healthcare and scientific research calls for models that are not only accurate but also interpretable. Among the…

Machine Learning · Computer Science 2025-10-23 Zhuo Cao , Xuan Zhao , Lena Krieger , Hanno Scharr , Ira Assent

Interpretable deep learning is a fundamental building block towards safer AI, especially when the deployment possibilities of deep learning-based computer-aided medical diagnostic systems are so eminent. However, without a computational…

Machine Learning · Computer Science 2018-06-27 Anirban Mukhopadhyay

Artificial intelligence holds great promise in medical imaging, especially histopathological imaging. However, artificial intelligence algorithms cannot fully explain the thought processes during decision-making. This situation has brought…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Tuncay Yiğit , Nilgün Şengöz , Özlem Özmen , Jude Hemanth , Ali Hakan Işık

Counterfactual image editing is an important task in generative AI, which asks how an image would look if certain features were different. The current literature on the topic focuses primarily on changing individual features while remaining…

Computer Vision and Pattern Recognition · Computer Science 2024-03-18 Yushu Pan , Elias Bareinboim

Automated radiology report generation holds immense potential to alleviate the heavy workload of radiologists. Despite the formidable vision-language capabilities of recent Multimodal Large Language Models (MLLMs), their clinical deployment…

Artificial Intelligence · Computer Science 2026-03-17 Tuoshi Qi , Shenshen Bu , Yingfei Xiang , Zhiming Dai

Deep neural networks (DNNs) have greatly impacted numerous fields over the past decade. Yet despite exhibiting superb performance over many problems, their black-box nature still poses a significant challenge with respect to explainability.…

Computer Vision and Pattern Recognition · Computer Science 2023-08-15 Snir Vitrack Tamam , Raz Lapid , Moshe Sipper