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In medical imaging, particularly in early disease detection and prognosis tasks, discerning the rationale behind an AI model's predictions is crucial for evaluating the reliability of its decisions. Conventional explanation methods face…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Yingying Fang , Zihao Jin , Xiaodan Xing , Simon Walsh , Guang Yang

We propose a BlackBox Counterfactual Explainer, designed to explain image classification models for medical applications. Classical approaches (e.g., saliency maps) that assess feature importance do not explain "how" imaging features in…

Computer Vision and Pattern Recognition · Computer Science 2022-11-21 Sumedha Singla , Motahhare Eslami , Brian Pollack , Stephen Wallace , Kayhan Batmanghelich

In this paper, we demonstrate the feasibility of alterfactual explanations for black box image classifiers. Traditional explanation mechanisms from the field of Counterfactual Thinking are a widely-used paradigm for Explainable Artificial…

Computer Vision and Pattern Recognition · Computer Science 2024-05-10 Silvan Mertes , Tobias Huber , Christina Karle , Katharina Weitz , Ruben Schlagowski , Cristina Conati , Elisabeth André

Despite their high accuracies, modern complex image classifiers cannot be trusted for sensitive tasks due to their unknown decision-making process and potential biases. Counterfactual explanations are very effective in providing…

Computer Vision and Pattern Recognition · Computer Science 2022-06-13 Kamran Alipour , Aditya Lahiri , Ehsan Adeli , Babak Salimi , Michael Pazzani

With the ongoing rise of machine learning, the need for methods for explaining decisions made by artificial intelligence systems is becoming a more and more important topic. Especially for image classification tasks, many state-of-the-art…

Machine Learning · Computer Science 2022-05-10 Silvan Mertes , Tobias Huber , Katharina Weitz , Alexander Heimerl , Elisabeth André

We present DiffExplainer, a novel framework that, leveraging language-vision models, enables multimodal global explainability. DiffExplainer employs diffusion models conditioned on optimized text prompts, synthesizing images that maximize…

Computer Vision and Pattern Recognition · Computer Science 2024-04-04 Matteo Pennisi , Giovanni Bellitto , Simone Palazzo , Mubarak Shah , Concetto Spampinato

Explaining decisions of black-box classifiers is paramount in sensitive domains such as medical imaging since clinicians confidence is necessary for adoption. Various explanation approaches have been proposed, among which perturbation based…

Computer Vision and Pattern Recognition · Computer Science 2020-12-15 Martin Charachon , Céline Hudelot , Paul-Henry Cournède , Camille Ruppli , Roberto Ardon

In recent years, deep learning models have been extensively applied to biological data across various modalities. Discriminative deep learning models have excelled at classifying images into categories (e.g., healthy versus diseased,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Anis Bourou , Saranga Kingkor Mahanta , Thomas Boyer , Valérie Mezger , Auguste Genovesio

Artificial intelligence is increasingly leveraged across various domains to automate decision-making processes that significantly impact human lives. In medical image analysis, deep learning models have demonstrated remarkable performance.…

Machine Learning · Computer Science 2025-07-28 Julia Siekiera , Stefan Kramer

Counterfactual explanations have emerged as a popular solution for the eXplainable AI (XAI) problem of elucidating the predictions of black-box deep-learning systems due to their psychological validity, flexibility across problem domains…

Machine Learning · Computer Science 2022-12-20 Eoin Delaney , Arjun Pakrashi , Derek Greene , Mark T. Keane

We present an approach to explain the decisions of black box models for image classification. While using the black box to label images, our explanation method exploits the latent feature space learned through an adversarial autoencoder.…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Riccardo Guidotti , Anna Monreale , Stan Matwin , Dino Pedreschi

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

Deep learning models used in medical image analysis are prone to raising reliability concerns due to their black-box nature. To shed light on these black-box models, previous works predominantly focus on identifying the contribution of…

Image and Video Processing · Electrical Eng. & Systems 2022-07-18 Matan Atad , Vitalii Dmytrenko , Yitong Li , Xinyue Zhang , Matthias Keicher , Jan Kirschke , Bene Wiestler , Ashkan Khakzar , Nassir Navab

In the realm of Artificial Intelligence (AI), the importance of Explainable Artificial Intelligence (XAI) is increasingly recognized, particularly as AI models become more integral to our lives. One notable single-instance XAI approach is…

Machine Learning · Computer Science 2024-06-03 Yukai Zhang , Ao Xu , Zihao Li , Tieru Wu

Understanding the predictions made by deep learning models remains a central challenge, especially in high-stakes applications. A promising approach is to equip models with the ability to answer counterfactual questions -- hypothetical…

Machine Learning · Computer Science 2025-10-28 Inwoo Hwang , Yushu Pan , Elias Bareinboim

Explainable AI consists in developing mechanisms allowing for an interaction between decision systems and humans by making the decisions of the formers understandable. This is particularly important in sensitive contexts like in the medical…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Carlo Metta , Riccardo Guidotti , Yuan Yin , Patrick Gallinari , Salvatore Rinzivillo

As machine learning methods see greater adoption and implementation in high stakes applications such as medical image diagnosis, the need for model interpretability and explanation has become more critical. Classical approaches that assess…

Machine Learning · Computer Science 2020-02-12 Sumedha Singla , Brian Pollack , Junxiang Chen , Kayhan Batmanghelich

We present CounterfactualExplanations.jl: a package for generating Counterfactual Explanations (CE) and Algorithmic Recourse (AR) for black-box models in Julia. CE explain how inputs into a model need to change to yield specific model…

Machine Learning · Computer Science 2023-08-15 Patrick Altmeyer , Arie van Deursen , Cynthia C. S. Liem

Deep learning models in medical imaging often fail when deployed in new clinical environments due to distribution shifts in demographics, scanner hardware, or acquisition protocols. A central challenge is underspecification, where models…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Moritz Stammel , Fabio De Sousa Ribeiro , Raghav Mehta , Mélanie Roschewitz , Ben Glocker

The remarkable success of deep learning has prompted interest in its application to medical imaging diagnosis. Even though state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Cristiano Patrício , João C. Neves , Luís F. Teixeira
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