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Related papers: Online t-SNE for single-cell RNA-seq

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Future link prediction is a fundamental challenge in various real-world dynamic systems. To address this, numerous temporal graph neural networks (temporal GNNs) and benchmark datasets have been developed. However, these datasets often…

Machine Learning · Computer Science 2025-03-18 Lu Yi , Jie Peng , Yanping Zheng , Fengran Mo , Zhewei Wei , Yuhang Ye , Yue Zixuan , Zengfeng Huang

We are in the era where the Big Data analytics has changed the way of interpreting the various biomedical phenomena, and as the generated data increase, the need for new machine learning methods to handle this evolution grows. An indicative…

Machine Learning · Computer Science 2020-12-04 Panagiotis Anagnostou , Petros T. Barmbas , Aristidis G. Vrahatis , Sotiris K. Tasoulis

t-Distributed Stochastic Neighbor Embedding (t-SNE) is one of the most widely used dimensionality reduction methods for data visualization, but it has a perplexity hyperparameter that requires manual selection. In practice, proper tuning of…

Artificial Intelligence · Computer Science 2017-08-11 Yanshuai Cao , Luyu Wang

Cluster visualization is an essential task for nonlinear dimensionality reduction as a data analysis tool. It is often believed that Student t-Distributed Stochastic Neighbor Embedding (t-SNE) can show clusters for well clusterable data,…

Machine Learning · Computer Science 2021-10-07 Zhirong Yang , Yuwei Chen , Jukka Corander

Single-cell RNA sequencing (scRNA-seq) has transformed our ability to explore biological systems. Nevertheless, proficient expertise is essential for handling and interpreting the data. In this paper, we present scX, an R package built on…

Widely used pipelines for analyzing high-dimensional data utilize two-dimensional visualizations. These are created, for instance, via t-distributed stochastic neighbor embedding (t-SNE). A crucial element of the t-SNE embedding procedure…

Machine Learning · Computer Science 2024-12-06 Martin Skrodzki , Nicolas F. Chaves-de-Plaza , Thomas Höllt , Elmar Eisemann , Klaus Hildebrandt

Single-cell RNA-Sequencing (scRNA-Seq) has undergone major technological advances in recent years, enabling the conception of various organism-level cell atlassing projects. With increasing numbers of datasets being deposited in public…

Single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to analyze gene expression at the resolution of individual cells, providing unprecedented insights into cellular heterogeneity and complex biological systems. This paper…

Other Quantitative Biology · Quantitative Biology 2024-06-11 Megha Patel , Nimish Magre , Himanshi Motwani , Nik Bear Brown

High-dimensional imaging is becoming increasingly relevant in many fields from astronomy and cultural heritage to systems biology. Visual exploration of such high-dimensional data is commonly facilitated by dimensionality reduction.…

Computer Vision and Pattern Recognition · Computer Science 2023-08-04 Alexander Vieth , Anna Vilanova , Boudewijn Lelieveldt , Elmar Eisemann , Thomas Höllt

Neighbor Embedding (NE) aims to preserve pairwise similarities between data items and has been shown to yield an effective principle for data visualization. However, even the best existing NE methods such as Stochastic Neighbor Embedding…

Machine Learning · Computer Science 2021-09-15 Zhirong Yang , Yuwei Chen , Denis Sedov , Samuel Kaski , Jukka Corander

Adversarial examples, designed to trick Artificial Neural Networks (ANNs) into producing wrong outputs, highlight vulnerabilities in these models. Exploring these weaknesses is crucial for developing defenses, and so, we propose a method to…

Machine Learning · Computer Science 2024-06-21 Inês Valentim , Nuno Antunes , Nuno Lourenço

T-distributed stochastic neighbour embedding (t-SNE) is a widely used data visualisation technique. It differs from its predecessor SNE by the low-dimensional similarity kernel: the Gaussian kernel was replaced by the heavy-tailed Cauchy…

Machine Learning · Computer Science 2020-07-20 Dmitry Kobak , George Linderman , Stefan Steinerberger , Yuval Kluger , Philipp Berens

Embedding and visualizing large-scale high-dimensional data in a two-dimensional space is an important problem since such visualization can reveal deep insights out of complex data. Most of the existing embedding approaches, however, run on…

Machine Learning · Computer Science 2017-03-06 Minjeong Kim , Minsuk Choi , Sunwoong Lee , Jian Tang , Haesun Park , Jaegul Choo

Nowadays, as data becomes increasingly complex and distributed, data analyses often involve several related datasets that are stored on different servers and probably owned by different stakeholders. While there is an emerging need to…

Cryptography and Security · Computer Science 2020-07-31 Jiazhi Xia , Tianxiang Chen , Lei Zhang , Wei Chen , Yang Chen , Xiaolong Zhang , Cong Xie , Tobias Schreck

Single-cell RNA-seq data analysis typically requires representations that capture heterogeneous local structure across multiple scales while remaining stable and interpretable. In this work, we propose a hierarchical sheaf spectral…

Machine Learning · Computer Science 2026-03-31 Xiang Xiang Wang , Guo-Wei We

The quality of GAN-generated images on the MNIST dataset was explored in this paper by comparing them to the original images using t-distributed stochastic neighbor embedding (t- SNE) visualization. A GAN was trained with the dataset to…

Computer Vision and Pattern Recognition · Computer Science 2023-05-18 Okan Düzyel

Representing the nodes of continuous-time temporal graphs in a low-dimensional latent space has wide-ranging applications, from prediction to visualization. Yet, analyzing continuous-time relational data with timestamped interactions…

Machine Learning · Computer Science 2024-05-28 Raphaël Romero , Jefrey Lijffijt , Riccardo Rastelli , Marco Corneli , Tijl De Bie

Across many scientific fields, measurements often represent the number of times an event occurs. For example, a document can be represented by word occurrence counts, neural activity by spike counts per time window, or online communication…

Machine Learning · Statistics 2026-04-21 Noga Mudrik , Adam S. Charles

Dimension reduction, widely used in science, maps high-dimensional data into low-dimensional space. We investigate a basic mathematical model underlying the techniques of stochastic neighborhood embedding (SNE) and its popular variant…

Machine Learning · Statistics 2025-03-26 Ben Weinkove

Network embedding is a very important method for network data. However, most of the algorithms can only deal with static networks. In this paper, we propose an algorithm Recurrent Neural Network Embedding (RNNE) to deal with dynamic…

Machine Learning · Computer Science 2020-07-01 Haiwei Huang , Jinlong Li , Huimin He , Huanhuan Chen