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Objective The concentration of bilirubin in blood or serum is useful for assessing liver function as well as monitoring treatment. This study evaluates the clinical performance of a novel point-of-care (PoC) device for the detection of…

A new and simple method of blood bilirubin detection through light reflection from skin is developed. The basic improvement over the existing methods is in the design of the light emitter and detector geometry which facilitates a two-stream…

Optics · Physics 2007-05-23 Bedrettin Subasilar

To perform precision medicine in realtime at home, a device capable of long distance continuously monitoring target biomolecules in unprocessed blood under dynamic situations is essential. In this study, an integrative buffer free wireless…

A low-cost, robust, and simple mechanism to measure hemoglobin would play a critical role in the modern health infrastructure. Consistent sample acquisition has been a long-standing technical hurdle for photometer-based portable hemoglobin…

Medical Physics · Physics 2017-12-04 Chris Wu , Tanay Tandon

Oscillometric monitors are the most common automated blood pressure (BP) measurement devices used in non-specialist settings. However, their accuracy and reliability vary under different settings and for different age groups and health…

Signal Processing · Electrical Eng. & Systems 2023-01-25 Niloufar Delfan , Mohamad Forouzanfar

Our growing ability to tailor healthcare to the needs of individuals has the potential to transform clinical treatment. However, the measurement of multiple biomarkers to inform clinical decisions requires rapid, effective, and affordable…

Brillouin imaging is increasingly recognized to be a powerful technique that enables non-invasive measurement of the mechanical properties of cells and tissues on a microscopic scale. This provides an unprecedented tool for investigating…

Biological Physics · Physics 2020-01-22 Christine Poon , Joshua Chou , Michael Cortie , Irina Kabakova

In this paper we present an acquisition chain for the measurement of blood arterial pressure based on the oscillometric method. This method does not suffer from any limitation as the well-known auscultatory method and it is suited for…

Medical Physics · Physics 2015-01-14 Gennaro Gelao , Roberto Marani , Vittorio M. N. Passaro , Anna Gina Perri

SPECT systems using pinhole apertures permit radiolabeled molecular distributions to be imaged in vivo in small animals. Nevertheless studying cardiovascular diseases by means of small animal models is very challenging. Specifically,…

It is known that diabetes can not be cured completely, but it can be controlled. The objective of this work is to provide an automatic system that will be able to help the diabetic patient to control the blood sugar. This system measures…

Computers and Society · Computer Science 2013-12-04 Pramit Ghosh , Debotosh Bhattacherjee , Mita Nasipuri , Dipak Kumar Basu

Noninvasive, non-contact and \textit{in vivo} monitoring of blood glucose is a long needed pathology tool for saving patients from recurring pain and hassle that can accompany conventional blood glucose testing methods. Optical coherence…

Biological Physics · Physics 2008-08-04 R Poddar , S R Sharma , P Sen , J T Andrews

Optical interferometry is amongst the most sensitive techniques for precision measurement. By increasing the light intensity a more precise measurement can usually be made. However, in some applications the sample is light sensitive. By…

Liver cirrhosis is an insidious condition involving the substitution of normal liver tissue with fibrous scar tissue and causing major health complications. The conventional method of diagnosis using liver biopsy is invasive and, therefore,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Kapil Kashyap , Sean Fargose , Chrisil Dabre , Fatema Dolaria , Nilesh Patil , Aniket Kore

Multispectral imaging (MSI) can provide information about tissue oxygenation, perfusion and potentially function during surgery. In this paper we present a novel, near real-time technique for intrinsic measurements of total haemoglobin…

Computer Vision and Pattern Recognition · Computer Science 2017-06-23 Geoffrey Jones , Neil T. Clancy , Yusuf Helo , Simon Arridge , Daniel S. Elson , Danail Stoyanov

Diabetes is one of the most debilitating and costly diseases currently plaguing humanity. It is a leading cause of death and dismemberment in the world, and we know how to treat it. Accurate, continuous monitoring and control of blood…

Biological Physics · Physics 2016-01-25 Brett H. Hokr , Carlos E. Tovar , Zhaokai Meng , Georgi I. Petrov , Vladislav V. Yakovlev

Despite existing for millennia, tuberculosis (TB) remains a persistent global health challenge. A significant obstacle in controlling TB spread is the need for a rapid, portable, sensitive, and accurate diagnostic test. Currently, sputum…

Medical Physics · Physics 2024-01-02 Ubaid Ullah , Seerat Saleem , Muddassar Farooq , Basit Yameen , M. Imran Cheema

Broadband NIRS (bNIRS) is an extension of fNIRS that provides the same assessment of oxygenation biomarkers along with a valuable marker for oxygen metabolism at a cellular level, the oxidation state of cytochrome-c-oxidase (oxCCO). bNIRS…

Pooling biomarker data across multiple studies enables researchers to get more precise estimates of the association between biomarker exposure measurements and disease risks due to increased sample sizes. However, biomarker measurements…

Methodology · Statistics 2019-11-22 Yujie Wu , Mitchell H. Gail , Stephanie A. Smith-Warner , Regina G. Ziegler , Molin Wang

A device based on Polarization sensitive optical coherence tomography is developed to monitor blood glucose levels in human subjects. The device was initially tested with tissue phantom. The measurements with human subjects for various…

Biological Physics · Physics 2015-06-04 Jitendra Solanki , OM Prakash Choudhury , Pratima Sen , Joseph Thomas Andrews

Imaging the brain vasculature can be critical for cerebral perfusion monitoring in the context of neurocritical care. Although ultrasensitive Doppler (UD) can provide good sensitivity to cerebral blood volume (CBV) in a large field of view,…

Neurons and Cognition · Quantitative Biology 2023-04-12 Anatole Jimenez , Bruno Osmanski , Denis Vivien , Mickael Tanter , Thomas Gaberel , Thomas Deffieux
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