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The organization of the axonal cytoskeleton is a key determinant of the normal function of an axon, which is a long thin projection away from a neuron. Under normal conditions two axonal cytoskeletal polymers microtubules and neurofilaments…
Classic models of cell size control consider cells divide while reaching a threshold, e.g. size, age, or size extension. The molecular basis of the threshold involves multiple layers of regulation as well as gene noises. In this work, we…
Our knowledge of the dynamics of stars has undergone a revolution thanks to the simultaneous large amount of high-quality photometric observations collected by space-based asteroseismology and ground-based high-precision spectropolarimetry.…
Two magnetic braking models are implemented in MESA for use in the MIST stellar model grids. Stars less than about 1.3 $M_{\odot}$ are observed to spin down over time through interaction with their magnetized stellar winds (i.e., magnetic…
Stellar evolution, a fundamental bedrock of modern astrophysics, is driven by the physical processes in stellar interiors. While we understand these processes in general terms, we lack some important ingredients. Seemingly small…
Many animal cells change their shape depending on the stiffness of the substrate on which they are cultured: they assume small, rounded shapes in soft ECMs, they elongate within stiffer ECMs, and flatten out on hard substrates. Cells tend…
Locomotion is essential for living cells. It enables bacteria and algae to explore space for food, cancer to spread, and immune system to fight infections. Motile cells display trajectories of intriguing complexity, from regular (e.g.…
An individual-based model of stochastic branching is proposed and studied, in which point particles drift in $\bar{\mathds{R}}_{+}:=[0,+\infty)$ towards the origin (edge) with unit speed, where each of them splits into two particles that…
Recent whole-brain calcium imaging recordings of the nematode C. elegans have demonstrated that neural activity is dominated by dynamics on a low-dimensional manifold that can be clustered according to behavioral states. Despite progress in…
Cellular Potts models are broadly applied across developmental biology and cancer research. We overcome limitations of the traditional approach, which reinterprets a modified Metropolis sampling as ad hoc dynamics, by introducing a physical…
We develop an energetic model that captures the twisting behavior of spindle-shaped polymer microparticles with nematic ordering, which display remarkably different twisting behavior to ordinary nematics confined to spindles. We have…
The cell cortex is a thin layer beneath the plasma membrane that gives animal cells mechanical resistance and drives most of their shape changes, from migration, division to multicellular morphogenesis. It is mainly composed of actin…
Cortical actin networks are highly dynamic and play critical roles in shaping the mechanical properties of cells. The actin cytoskeleton undergoes significant reorganization over the course of the cell cycle, when cortical actin transitions…
Asteroseismology is a powerful way of determining stellar parameters and properties of stars like the Sun. However, main-sequence F-type stars exhibit short mode lifetimes relative to their oscillation frequency, resulting in overlapping…
We develop new angular momentum evolution models for stars with masses of $0.5$ to $1.6~\rm M_\odot$ and from the pre-main-sequence (\rm PMS) through the end of their main-sequence (\rm MS) lifetime. The parametric models include magnetic…
Understanding how multicellular organisms reliably orchestrate cell-fate decisions is a central challenge in developmental biology. This is particularly intriguing in early mammalian development, where early cell-lineage differentiation…
We consider a class of biologically-motivated stochastic processes in which a unicellular organism divides its resources (volume or damaged proteins, in particular) symmetrically or asymmetrically between its progeny. Assuming the final…
Experimental research has shown that the brain's fast electrochemical dynamics, or neurodynamics (ND), is strongly stochastic, chaotic, and instanton (neuroavalanche)-dominated. It is also partly scale-invariant which has been loosely…
Spatiotemporal patterns are common in biological systems. For electrically-coupled cells previous studies of pattern formation have mainly used external forcing as the main bifurcation parameter. The purpose of this paper is to show that…
Ever since the ground breaking work of Trepat et al. in 2009, we know that cell colonies growing on a substrate can be under tensile mechanical stress. The origin of tension has so far been attributed to cellular motility forces being…