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Large language models (LLMs) have made significant progress in various domains, including healthcare. However, the specialized nature of clinical language understanding tasks presents unique challenges and limitations that warrant further…

Computation and Language · Computer Science 2023-08-01 Yuqing Wang , Yun Zhao , Linda Petzold

Large language models (LLMs) are introducing a paradigm shift in molecular discovery by enabling text-guided interaction with chemical spaces through natural language, symbolic notations, with emerging extensions to incorporate multi-modal…

Machine Learning · Computer Science 2025-05-23 Ziqing Wang , Kexin Zhang , Zihan Zhao , Yibo Wen , Abhishek Pandey , Han Liu , Kaize Ding

We present MeshLLM, a novel framework that leverages large language models (LLMs) to understand and generate text-serialized 3D meshes. Our approach addresses key limitations in existing methods, including the limited dataset scale when…

Recent years have witnessed remarkable progress in multimodal learning within computational pathology. Existing models primarily rely on vision and language modalities; however, language alone lacks molecular specificity and offers limited…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Minghao Han , Dingkang Yang , Linhao Qu , Zizhi Chen , Gang Li , Han Wang , Jiacong Wang , Lihua Zhang

Large language models (LLMs) have demonstrated remarkable capabilities across various domains, yet their application to relational deep learning (RDL) remains underexplored. Existing approaches adapt LLMs by traversing relational links…

Computation and Language · Computer Science 2025-06-09 Fang Wu , Vijay Prakash Dwivedi , Jure Leskovec

Current protein language models (PLMs) learn protein representations mainly based on their sequences, thereby well capturing co-evolutionary information, but they are unable to explicitly acquire protein functions, which is the end goal of…

Biomolecules · Quantitative Biology 2023-07-06 Minghao Xu , Xinyu Yuan , Santiago Miret , Jian Tang

Large language models (LLMs) are advancing rapidly. Such models have demonstrated strong capabilities in learning from large-scale (unstructured) text data and answering user queries. Users do not need to be experts in structured query…

Databases · Computer Science 2023-10-02 Jianzhong Qi , Zuqing Li , Egemen Tanin

Large Language models (LLMs) have emerged as powerful tools for addressing challenges across diverse domains. Notably, recent studies have demonstrated that large language models significantly enhance the efficiency of biomolecular analysis…

Computation and Language · Computer Science 2025-03-07 Jiyue Jiang , Zikang Wang , Yuheng Shan , Heyan Chai , Jiayi Li , Zixian Ma , Xinrui Zhang , Yu Li

Large language models (LLMs) are playing an increasingly important role in science and engineering. For example, their ability to parse and understand human and computer languages makes them powerful interpreters and their use in…

Materials Science · Physics 2023-10-19 Juan C. Verduzco , Ethan Holbrook , Alejandro Strachan

The growing scarcity of spectrum resources and rapid proliferation of wireless devices make efficient radio network management critical. While deep learning-enhanced Cognitive Radio Technology (CRT) provides promising solutions for tasks…

Signal Processing · Electrical Eng. & Systems 2025-05-14 Shuai Chen , Yong Zu , Zhixi Feng , Shuyuan Yang , Mengchang Li

Large Language Models (LLMs) have the potential to revolutionize data analytics by simplifying tasks such as data discovery and SQL query synthesis through natural language interactions. This work serves as a pivotal first step toward the…

This paper explores the use of large language models (LLMs) as research tools in the history, philosophy, and sociology of science (HPSS). LLMs are remarkably effective at processing unstructured text and inferring meaning from context,…

Computation and Language · Computer Science 2025-06-17 Arno Simons , Michael Zichert , Adrian Wüthrich

Pre-trained Language Models (PLMs), such as ChatGPT, have significantly advanced the field of natural language processing. This progress has inspired a series of innovative studies that explore the adaptation of PLMs to time series…

Artificial Intelligence · Computer Science 2025-06-06 Weijia Zhang , Chenlong Yin , Hao Liu , Hui Xiong

Large Language Models (LLMs) have made remarkable advancements in the field of natural language processing. However, their increasing size poses challenges in terms of computational cost. On the other hand, Small Language Models (SLMs) are…

Computation and Language · Computer Science 2023-08-03 Zhen Guo , Peiqi Wang , Yanwei Wang , Shangdi Yu

Large language models (LLMs) demonstrate extraordinary abilities in a wide range of natural language processing (NLP) tasks. In this paper, we show that, beyond text understanding capability, LLMs are capable of processing text layouts that…

Computation and Language · Computer Science 2024-08-29 Weiming Li , Manni Duan , Dong An , Yan Shao

We propose STRuCT-LLM, a unified framework for training large language models (LLMs) to perform structured reasoning over both relational and graph-structured data. Our approach jointly optimizes Text-to-SQL and Text-to-Cypher tasks using…

Computation and Language · Computer Science 2025-06-30 Josefa Lia Stoisser , Marc Boubnovski Martell , Lawrence Phillips , Casper Hansen , Julien Fauqueur

Capturing spatial relationships from visual inputs is a cornerstone of human-like general intelligence. Several previous studies have tried to enhance the spatial awareness of Vision-Language Models (VLMs) by adding extra expert encoders,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Rui Yang , Ziyu Zhu , Yanwei Li , Jingjia Huang , Shen Yan , Siyuan Zhou , Zhe Liu , Xiangtai Li , Shuangye Li , Wenqian Wang , Yi Lin , Hengshuang Zhao

While Large Language Models (LLMs) have achieved remarkable success in various fields, the efficiency of training and inference remains a major challenge. To address this issue, we propose SUBLLM, short for Subsampling-Upsampling-Bypass…

Computation and Language · Computer Science 2024-08-26 Quandong Wang , Yuxuan Yuan , Xiaoyu Yang , Ruike Zhang , Kang Zhao , Wei Liu , Jian Luan , Daniel Povey , Bin Wang

A growing trend has emerged in designing high-quality Small Language Models (SLMs) with a few million parameters. This trend is driven by the increasing concerns over cloud costs, privacy, and latency. Considering that full parameter…

Machine Learning · Computer Science 2025-07-03 Xuan Shen , Peiyan Dong , Zhenglun Kong , Yifan Gong , Changdi Yang , Zhaoyang Han , Yanyue Xie , Lei Lu , Cheng Lyu , Chao Wu , Yanzhi Wang , Pu Zhao

We introduce QSTN, an open-source Python framework for systematically generating responses from questionnaire-style prompts to support in-silico surveys and annotation tasks with large language models (LLMs). QSTN enables robust evaluation…

Computation and Language · Computer Science 2026-02-20 Maximilian Kreutner , Jens Rupprecht , Georg Ahnert , Ahmed Salem , Markus Strohmaier
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