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Active Learning (AL) techniques aim to minimize the training data required to train a model for a given task. Pool-based AL techniques start with a small initial labeled pool and then iteratively pick batches of the most informative samples…

Machine Learning · Computer Science 2021-07-15 Akshay L Chandra , Sai Vikas Desai , Chaitanya Devaguptapu , Vineeth N Balasubramanian

A new empirical potential for efficient, large scale molecular dynamics simulation of water is presented. The HIPPO (Hydrogen-like Intermolecular Polarizable POtential) force field is based upon the model electron density of a hydrogen-like…

Chemical Physics · Physics 2021-09-30 Joshua A. Rackers , Roseane R. Silva , Zhi Wang , Jay W. Ponder

We present a multiscale simulation of liquid water where a spatially adaptive molecular resolution procedure allows for changing on-the-fly from a coarse-grained to an all-atom representation. We show that this approach leads to the correct…

Soft Condensed Matter · Physics 2007-07-09 Matej Praprotnik , Luigi Delle Site , Kurt Kremer , Silvina Matysiak , Cecilia Clementi

We demonstrate for the first time a tight binding model for water incorporating polarizable anions. A novel aspect is that we adopt a "ground up" approach in that properties of the monomer and dimer only are fitted. Subsequently we make…

Materials Science · Physics 2015-05-20 A. T. Paxton , J. J. Kohanoff

Electrochemical interfaces are of fundamental importance in electrocatalysis, batteries, and metal corrosion. Finite-field methods are one of most reliable approaches for modeling electrochemical interfaces in complete cells under realistic…

Chemical Physics · Physics 2025-06-13 Chaoqiang Feng , Bin Jiang

Liquid water exhibits several important anomalous properties in the vicinity of the melting temperature ($T_{\mathrm{m}}$) of ice Ih, including a higher density than ice and a density maximum at 4~$^{\circ}$C. Experimentally, an isotope…

Chemical Physics · Physics 2026-01-01 Yifan Li , Bingjia Yang , Chunyi Zhang , Axel Gomez , Pinchen Xie , Yixiao Chen , Pablo M. Piaggi , Roberto Car

A ubiquitous approach to obtain transferable machine learning-based models of potential energy surfaces for atomistic systems is to decompose the total energy into a sum of local atom-centred contributions. However, in many systems…

Computational Physics · Physics 2024-06-18 Jack Thomas , William J. Baldwin , Gábor Csányi , Christoph Ortner

Quantitative prediction of thermodynamic properties in solution is essential for translating atomistic simulations into reliable chemical insight. As an exemplar system, the behaviour of CaCO$_3$ in water has been widely studied to…

Even though atomistic and coarse-grained (CG) models have been used to simulate liquid nanodroplets in vapor, very few rigorous studies of the liquid-liquid interface structure are available, and most of them are limited to planar…

Chemical Physics · Physics 2019-07-16 Peiyuan Gao , Xiu Yang , Alexandre M. Tartakovsky

Experiment Directed Simulations (EDS) is a method within a class of techniques seeking to improve molecular simulations by minimally biasing the system Hamiltonian to reproduce certain experimental observables. In a previous application of…

Chemical Physics · Physics 2020-06-04 Paul B. Calio , Glen M. Hocky , Gregory A. Voth

We study the convergence of a linear atomic cluster expansion (ACE) potential with respect to its basis functions, in terms of the effective two-body interactions of elemental Carbon and Silicon systems. We build ACE potentials with…

Computational Physics · Physics 2025-07-30 Apolinario Miguel Tan , Franco Pellegrini , Stefano de Gironcoli

A new technique for on-line high resolution isotopic analysis of liquid water, tailored for ice core studies is presented. We built an interface between a Wavelength Scanned Cavity Ring Down Spectrometer (WS-CRDS) purchased from Picarro…

Instrumentation and Detectors · Physics 2014-04-24 V. Gkinis , T. J. Popp , T. Blunier , M. Bigler , S. Schüpbach , E. Kettner , S. J. Johnsen

Simulations of chemical reaction probabilities in gas surface dynamics require the calculation of ensemble averages over many tens of thousands of reaction events to predict dynamical observables that can be compared to experiments. At the…

Water is of the utmost importance for life and technology. However, a genuinely predictive ab initio model of water has eluded scientists. We demonstrate that a fully ab initio approach, relying on the strongly constrained and appropriately…

Flow and diffusion models achieve high-fidelity, high-resolution image synthesis, but often require many function evaluations (NFEs) at sampling time. Existing acceleration methods either require additional training through distillation or…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Anuska Roy , Pravin Nair

We present an investigation into data selection methods for the efficient sampling of configuration space as applied to the development of inter-atomic potentials for scale bridging in molecular dynamics (MD) simulations. This investigation…

Computational Physics · Physics 2021-08-04 Jan Finkbeiner , Samuel Tovey , Christian Holm

Non-equilibrium molecular dynamics (NEMD) techniques are widely used for investigating lattice thermal conductivity. Recently, machine learning force fields (MLFFs) have emerged as a promising approach to enhance the precision in NEMD…

Materials Science · Physics 2023-09-21 Takumi Araki , Shinnosuke Hattori , Toshio Nishi , Yoshihiro Kudo

In recent years, significant progress has been made in the development of machine learning potentials (MLPs) for atomistic simulations with applications in many fields from chemistry to materials science. While most current MLPs are based…

Chemical Physics · Physics 2023-05-19 Tsz Wai Ko , Jonas A. Finkler , Stefan Goedecker , Jörg Behler

We derive an adaptive hierarchical method of estimating high dimensional probability density functions. We call this method of density estimation the "adaptive cluster expansion" or ACE for short. We present an application of this approach,…

Neural and Evolutionary Computing · Computer Science 2010-12-17 Stephen Luttrell

Accurate thermochemical data with sub-chemical accuracy (within 1 kcal mol$^{-1}$ of the empirical ground truth) are essential for advancing computational chemistry methods. However, existing datasets that reach this level of accuracy…

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