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Accurate medical image segmentation commonly requires effective learning of the complementary information from multimodal data. However, in clinical practice, we often encounter the problem of missing imaging modalities. We tackle this…

Computer Vision and Pattern Recognition · Computer Science 2020-02-25 Cheng Chen , Qi Dou , Yueming Jin , Hao Chen , Jing Qin , Pheng-Ann Heng

Breast histology image classification is a crucial step in the early diagnosis of breast cancer. In breast pathological diagnosis, Convolutional Neural Networks (CNNs) have demonstrated great success using digitized histology slides.…

Computer Vision and Pattern Recognition · Computer Science 2021-08-25 Zakaria Senousy , Mohammed M. Abdelsamea , Mohamed Medhat Gaber , Moloud Abdar , U Rajendra Acharya , Abbas Khosravi , Saeid Nahavandi

Due to the difficulties of obtaining multimodal paired images in clinical practice, recent studies propose to train brain tumor segmentation models with unpaired images and capture complementary information through modality translation.…

Computer Vision and Pattern Recognition · Computer Science 2022-08-29 Zecheng Liu , Jia Wei , Rui Li

Breast cancer is a heterogeneous disease with different molecular subtypes, clinical behavior, treatment responses as well as survival outcomes. The development of a reliable, accurate, available and inexpensive method to predict the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Mohaddeseh Chegini , Ali Mahloojifar

Emerging research has highlighted that artificial intelligence-based multimodal fusion of digital pathology and transcriptomic features can improve cancer diagnosis (grading/subtyping) and prognosis (survival risk) prediction. However, such…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Samiran Dey , Christopher R. S. Banerji , Partha Basuchowdhuri , Sanjoy K. Saha , Deepak Parashar , Tapabrata Chakraborti

To improve the prediction of cancer survival using whole-slide images and transcriptomics data, it is crucial to capture both modality-shared and modality-specific information. However, multimodal frameworks often entangle these…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Aniek Eijpe , Soufyan Lakbir , Melis Erdal Cesur , Sara P. Oliveira , Sanne Abeln , Wilson Silva

Computer-aided cancer survival risk prediction plays an important role in the timely treatment of patients. This is a challenging weakly supervised ordinal regression task associated with multiple clinical factors involved such as…

Machine Learning · Computer Science 2024-09-05 Zekang Yang , Hong Liu , Xiangdong Wang

Lung cancer remains one of the leading causes of cancer-related mortality worldwide. Conventional computed tomography (CT) imaging, while essential for detection and staging, has limitations in distinguishing benign from malignant lesions…

Image and Video Processing · Electrical Eng. & Systems 2026-04-20 Baramee Sukumal , Aueaphum Aueawatthanaphisut

Developing effective path representations has become increasingly essential across various fields within intelligent transportation. Although pre-trained path representation learning models have shown improved performance, they…

Machine Learning · Computer Science 2025-01-03 Ronghui Xu , Hanyin Cheng , Chenjuan Guo , Hongfan Gao , Jilin Hu , Sean Bin Yang , Bin Yang

Automatic brain tumor segmentation from multi-modality Magnetic Resonance Images (MRI) using deep learning methods plays an important role in assisting the diagnosis and treatment of brain tumor. However, previous methods mostly ignore the…

Image and Video Processing · Electrical Eng. & Systems 2021-01-01 Yixin Wang , Yao Zhang , Feng Hou , Yang Liu , Jiang Tian , Cheng Zhong , Yang Zhang , Zhiqiang He

Multi-modal learning is a fast growing area in artificial intelligence. It tries to help machines understand complex things by combining information from different sources, like images, text, and audio. By using the strengths of each…

Machine Learning · Computer Science 2025-12-22 Qihang Jin , Enze Ge , Yuhang Xie , Hongying Luo , Junhao Song , Ziqian Bi , Chia Xin Liang , Jibin Guan , Joe Yeong , Xinyuan Song , Junfeng Hao

Multimodal learning has developed very fast in recent years. However, during the multimodal training process, the model tends to rely on only one modality based on which it could learn faster, thus leading to inadequate use of other…

Machine Learning · Computer Science 2024-11-05 Zirun Guo , Tao Jin , Jingyuan Chen , Zhou Zhao

Brain tumor segmentation requires accurate identification of hierarchical regions including whole tumor (WT), tumor core (TC), and enhancing tumor (ET) from multi-sequence magnetic resonance imaging (MRI) images. Due to tumor tissue…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Mingda Zhang , Yuyang Zheng , Ruixiang Tang , Jingru Qiu , Haiyan Ding

Statistical inference on the cancer-site specificities of collective ultra-rare whole genome somatic mutations is an open problem. Traditional statistical methods cannot handle whole-genome mutation data due to their…

Methodology · Statistics 2023-01-02 Saptarshi Chakraborty , Zoe Guan , Colin B. Begg , Ronglai Shen

Deep learning methods have achieved impressive performance for multi-class medical image segmentation. However, they are limited in their ability to encode topological interactions among different classes (e.g., containment and exclusion).…

Brain tumour segmentation plays a key role in computer-assisted surgery. Deep neural networks have increased the accuracy of automatic segmentation significantly, however these models tend to generalise poorly to different imaging…

Computer Vision and Pattern Recognition · Computer Science 2017-09-06 Lucas Fidon , Wenqi Li , Luis C. Garcia-Peraza-Herrera , Jinendra Ekanayake , Neil Kitchen , Sebastien Ourselin , Tom Vercauteren

We propose a new deep learning method for tumour segmentation when dealing with missing imaging modalities. Instead of producing one network for each possible subset of observed modalities or using arithmetic operations to combine feature…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Reuben Dorent , Samuel Joutard , Marc Modat , Sébastien Ourselin , Tom Vercauteren

Cancer prognosis and survival outcome predictions are crucial for therapeutic response estimation and for stratifying patients into various treatment groups. Medical domains concerned with cancer prognosis are abundant with multiple…

Image and Video Processing · Electrical Eng. & Systems 2024-02-29 Ruining Deng , Nazim Shaikh , Gareth Shannon , Yao Nie

Background: Brain tumor segmentation requires precise delineation of hierarchical structures from multi-sequence MRI. However, existing deep learning methods primarily rely on visual features, showing insufficient discriminative power in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-13 Mingda Zhang , Kaiwen Pan

The Cancer Genome Atlas (TCGA) has enabled novel discoveries and served as a large-scale reference dataset in cancer through its harmonized genomics, clinical, and imaging data. Numerous prior studies have developed bespoke deep learning…

Machine Learning · Computer Science 2026-05-11 Steven Song , Morgan Borjigin-Wang , Irene Madejski , Robert L. Grossman
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