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Electronic Health Records (EHRs) are rich sources of patient-level data, offering valuable resources for medical data analysis. However, privacy concerns often restrict access to EHRs, hindering downstream analysis. Current EHR…

Machine Learning · Computer Science 2024-12-03 Muhang Tian , Bernie Chen , Allan Guo , Shiyi Jiang , Anru R. Zhang

Due to patient privacy protection concerns, machine learning research in healthcare has been undeniably slower and limited than in other application domains. High-quality, realistic, synthetic electronic health records (EHRs) can be…

Machine Learning · Computer Science 2023-02-10 Huan He , Shifan Zhao , Yuanzhe Xi , Joyce C Ho

Electronic health records (EHR) contain a wealth of biomedical information, serving as valuable resources for the development of precision medicine systems. However, privacy concerns have resulted in limited access to high-quality and…

Machine Learning · Computer Science 2024-03-26 Hongyi Yuan , Songchi Zhou , Sheng Yu

This paper presents a novel approach to simulating electronic health records (EHRs) using diffusion probabilistic models (DPMs). Specifically, we demonstrate the effectiveness of DPMs in synthesising longitudinal EHRs that capture…

Machine Learning · Computer Science 2023-03-23 Nicholas I-Hsien Kuo , Louisa Jorm , Sebastiano Barbieri

Electronic Health Records (EHRs) contain sensitive patient information, which presents privacy concerns when sharing such data. Synthetic data generation is a promising solution to mitigate these risks, often relying on deep generative…

Machine Learning · Computer Science 2023-08-11 Taha Ceritli , Ghadeer O. Ghosheh , Vinod Kumar Chauhan , Tingting Zhu , Andrew P. Creagh , David A. Clifton

Electronic health records (EHRs) are invaluable for clinical research, yet privacy concerns severely restrict data sharing. Synthetic data generation offers a promising solution, but EHRs present unique challenges: they contain both…

Machine Learning · Computer Science 2026-03-26 Shaonan Liu , Yuichiro Iwashita , Soichiro Nakako , Masakazu Iwamura , Koichi Kise

Electronic health records (EHRs) are a pivotal data source that enables numerous applications in computational medicine, e.g., disease progression prediction, clinical trial design, and health economics and outcomes research. Despite wide…

Machine Learning · Computer Science 2024-06-18 Jun Han , Zixiang Chen , Yongqian Li , Yiwen Kou , Eran Halperin , Robert E. Tillman , Quanquan Gu

Synthetic Electronic Health Records (EHR) have emerged as a pivotal tool in advancing healthcare applications and machine learning models, particularly for researchers without direct access to healthcare data. Although existing methods,…

Synthetic Electronic Health Record (EHR) time-series generation is crucial for advancing clinical machine learning models, as it helps address data scarcity by providing more training data. However, most existing approaches focus primarily…

Machine Learning · Computer Science 2025-04-25 Bowen Deng , Chang Xu , Hao Li , Yuhao Huang , Min Hou , Jiang Bian

Accessing longitudinal multimodal Electronic Healthcare Records (EHRs) is challenging due to privacy concerns, which hinders the use of ML for healthcare applications. Synthetic EHRs generation bypasses the need to share sensitive real…

Computation and Language · Computer Science 2022-11-04 Zifeng Wang , Jimeng Sun

Synthetic Electronic Health Record (EHR) generation provides a promising avenue for data augmentation and cross-hospital modeling in privacy-constrained healthcare settings. However, most existing EHR generative models are centralized and…

Machine Learning · Computer Science 2026-05-28 Jun Bai , Ziyang Song , Yue Li

The recent availability of electronic health records (EHRs) have provided enormous opportunities to develop artificial intelligence (AI) algorithms. However, patient privacy has become a major concern that limits data sharing across…

Machine Learning · Computer Science 2023-02-01 Jin Li , Benjamin J. Cairns , Jingsong Li , Tingting Zhu

Health risk prediction is one of the fundamental tasks under predictive modeling in the medical domain, which aims to forecast the potential health risks that patients may face in the future using their historical Electronic Health Records…

Machine Learning · Computer Science 2023-10-09 Yuan Zhong , Suhan Cui , Jiaqi Wang , Xiaochen Wang , Ziyi Yin , Yaqing Wang , Houping Xiao , Mengdi Huai , Ting Wang , Fenglong Ma

Generative models have been found effective for data synthesis due to their ability to capture complex underlying data distributions. The quality of generated data from these models is commonly evaluated by visual inspection for image…

Machine Learning · Computer Science 2022-10-18 Emily Muller , Xu Zheng , Jer Hayes

Synthetic health data have the potential to mitigate privacy concerns when sharing data to support biomedical research and the development of innovative healthcare applications. Modern approaches for data generation based on machine…

Machine Learning · Computer Science 2023-01-11 Chao Yan , Yao Yan , Zhiyu Wan , Ziqi Zhang , Larsson Omberg , Justin Guinney , Sean D. Mooney , Bradley A. Malin

Electronic health records (EHRs) have become the foundation of machine learning applications in healthcare, while the utility of real patient records is often limited by privacy and security concerns. Synthetic EHR generation provides an…

Artificial Intelligence · Computer Science 2023-12-25 Hongda Sun , Hongzhan Lin , Rui Yan

Electronic Health Records (EHRs) are commonly used by the machine learning community for research on problems specifically related to health care and medicine. EHRs have the advantages that they can be easily distributed and contain many…

Machine Learning · Computer Science 2020-06-08 Kieran Chin-Cheong , Thomas Sutter , Julia E. Vogt

Advanced healthcare predictions offer significant improvements in patient outcomes by leveraging predictive analytics. Existing works primarily utilize various views of Electronic Health Record (EHR) data, such as diagnoses, lab tests, or…

Machine Learning · Computer Science 2025-05-20 Chuang Zhao , Hui Tang , Hongke Zhao , Xiaomeng Li

The scarcity of large-scale and high-quality electronic health records (EHRs) remains a major bottleneck in biomedical research, especially as large foundation models become increasingly data-hungry. Synthesizing substantial volumes of…

Machine Learning · Computer Science 2025-08-05 Yandong Yan , Chenxi Li , Yu Huang , Dexuan Xu , Jiaqi Zhu , Zhongyan Chai , Huamin Zhang

The development of electronic health records (EHR) systems has enabled the collection of a vast amount of digitized patient data. However, utilizing EHR data for predictive modeling presents several challenges due to its unique…

Machine Learning · Computer Science 2024-08-14 Jiaqi Wang , Junyu Luo , Muchao Ye , Xiaochen Wang , Yuan Zhong , Aofei Chang , Guanjie Huang , Ziyi Yin , Cao Xiao , Jimeng Sun , Fenglong Ma
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