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Missing data in supervised learning is well-studied, but the specific issue of missing labels during model evaluation has been overlooked. Ignoring samples with missing values, a common solution, can introduce bias, especially when data is…

Machine Learning · Computer Science 2025-04-28 Danial Dervovic , Michael Cashmore

We study the problem of maximum likelihood estimation for general patterns of bivariate missing data for normal and multinomial random variables, under the assumption that the data is missing at random (MAR). For normal data, the score…

Statistics Theory · Mathematics 2007-09-07 Serkan Hosten , Seth Sullivant

This paper establishes a series of sensitivity analyses to investigate the impact of missing values in the electronic health records (EHR) that are possibly missing not at random (MNAR). EHRs have gained tremendous interest due to their…

Methodology · Statistics 2025-03-28 Jungwun Lee , Sebastien Haneuse , Rajarshi Mukherjee , Tanayott Thaweethai

We propose a novel targeted maximum likelihood estimator (TMLE) for quantiles in semiparametric missing data models. Our proposed estimator is locally efficient, $\sqrt{n}$-consistent, asymptotically normal, and doubly robust, under…

Methodology · Statistics 2016-08-23 Iván Díaz

Data missing not at random (MNAR) is a major challenge in survey sampling. We propose an approach based on registry data to deal with non-ignorable missingness in health examination surveys. The approach relies on follow-up data available…

Applications · Statistics 2016-10-31 Juho Kopra , Tommi Härkänen , Hanna Tolonen , Juha Karvanen

During the past few decades, missing-data problems have been studied extensively, with a focus on the ignorable missing case, where the missing probability depends only on observable quantities. By contrast, research into non-ignorable…

Methodology · Statistics 2019-08-06 Yukun Liu , Pengfei Li , Jing Qin

Adversarial Missingness (AM) attacks aim to manipulate model fitting by carefully engineering a missing data problem to achieve a specific malicious objective. AM attacks are significantly different from prior data poisoning attacks in that…

Machine Learning · Computer Science 2025-11-18 Deniz Koyuncu , Alex Gittens , Bülent Yener , Moti Yung

We study targeted maximum likelihood estimation (TMLE) of the average treatment effect in a semiparametric regression model whose mean function is indexed by a finite-dimensional parameter, while the additive error distribution is left…

Methodology · Statistics 2026-04-20 Mijeong Kim

In epidemiological surveys, data missing not at random (MNAR) due to survey nonresponse may potentially lead to a bias in the risk factor estimates. We propose an approach based on Bayesian data augmentation and survival modelling to reduce…

Methodology · Statistics 2017-08-29 Juho Kopra , Juha Karvanen , Tommi Härkänen

In clinical trials, mixed effects models for repeated measures (MMRM) and pattern mixture models (PMM) are often used to analyze longitudinal continuous outcomes. We describe a simple missing data imputation algorithm for the MMRM that can…

Methodology · Statistics 2016-10-13 Yongqiang Tang

Semi-Supervised Learning (SSL) is fundamentally a missing label problem, in which the label Missing Not At Random (MNAR) problem is more realistic and challenging, compared to the widely-adopted yet naive Missing Completely At Random…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Xinting Hu , Yulei Niu , Chunyan Miao , Xian-Sheng Hua , Hanwang Zhang

We consider missing data in the context of hidden Markov models with a focus on situations where data is missing not at random (MNAR) and missingness depends on the identity of the hidden states. In simulations, we show that including a…

Methodology · Statistics 2021-09-08 Maarten Speekenbrink , Ingmar Visser

Trial-based cost-effectiveness analyses (CEAs) are an important source of evidence in the assessment of health interventions. In these studies, cost and effectiveness outcomes are commonly measured at multiple time points, but some…

Methodology · Statistics 2022-03-30 Andrea Gabrio , Catrin Plumpton , Sube Banerjee , Baptiste Leurent

Missing data is a fundamental challenge in data science, significantly hindering analysis and decision-making across a wide range of disciplines, including healthcare, bioinformatics, social science, e-commerce, and industrial monitoring.…

Machine Learning · Statistics 2026-05-12 Jicong Fan

A multivariate mixed-effects model seems to be the most appropriate for gene expression data collected in a crossover trial. It is, however, difficult to obtain reliable results using standard statistical inference when some responses are…

Methodology · Statistics 2023-09-12 Savita Pareek , Kalyan Das , Siuli Mukhopadhyay

Missing data is an expected issue when large amounts of data is collected, and several imputation techniques have been proposed to tackle this problem. Beneath classical approaches such as MICE, the application of Machine Learning…

Machine Learning · Statistics 2017-12-01 Burim Ramosaj , Markus Pauly

Multiple imputation (MI) is a popular approach for dealing with missing data arising from non-response in sample surveys. Multiple imputation by chained equations (MICE) is one of the most widely used MI algorithms for multivariate data,…

Machine Learning · Computer Science 2022-03-22 Zhenhua Wang , Olanrewaju Akande , Jason Poulos , Fan Li

The presence of missing values makes supervised learning much more challenging. Indeed, previous work has shown that even when the response is a linear function of the complete data, the optimal predictor is a complex function of the…

Machine Learning · Computer Science 2020-11-05 Marine Le Morvan , Julie Josse , Thomas Moreau , Erwan Scornet , Gaël Varoquaux

The amount of data for machine learning (ML) applications is constantly growing. Not only the number of observations, especially the number of measured variables (features) increases with ongoing digitization. Selecting the most appropriate…

Machine Learning · Computer Science 2021-11-25 Konstantin Hopf , Sascha Reifenrath

Generalized Estimation Equations (GEE) are a well-known method for the analysis of non-Gaussian longitudinal data. This method has computational simplicity and marginal parameter interpretation. However, in the presence of missing data, it…

Methodology · Statistics 2015-06-16 José Luiz P. da Silva , Enrico A. Colosimo , Fábio N. Demarqui
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