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Diffusion models have emerged as a powerful class of generative models for molecular design, capable of capturing complex structural distributions and achieving high fidelity in 3D molecule generation. However, their widespread use remains…

Machine Learning · Computer Science 2026-01-15 Adrita Das , Peiran Jiang , Dantong Zhu , Barnabas Poczos , Jose Lugo-Martinez

Many inverse problems are ill-posed and need to be complemented by prior information that restricts the class of admissible models. Bayesian approaches encode this information as prior distributions that impose generic properties on the…

Machine Learning · Computer Science 2024-12-20 Julian L. Möbius , Michael Habeck

Graph generative models have broad applications in biology, chemistry and social science. However, modelling and understanding the generative process of graphs is challenging due to the discrete and high-dimensional nature of graphs, as…

Machine Learning · Computer Science 2022-12-06 Han Huang , Leilei Sun , Bowen Du , Yanjie Fu , Weifeng Lv

How do diffusion generative models convert pure noise into meaningful images? In a variety of pretrained diffusion models (including conditional latent space models like Stable Diffusion), we observe that the reverse diffusion process that…

Computer Vision and Pattern Recognition · Computer Science 2024-03-27 Binxu Wang , John J. Vastola

Diffusion models (DMs) are a powerful generative framework that have attracted significant attention in recent years. However, the high computational cost of training DMs limits their practical applications. In this paper, we start with a…

Machine Learning · Computer Science 2024-04-12 Tianshuo Xu , Peng Mi , Ruilin Wang , Yingcong Chen

Sparse-view computed tomography (CT) reconstruction is fundamentally challenging due to undersampling, leading to an ill-posed inverse problem. Traditional iterative methods incorporate handcrafted or learned priors to regularize the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Leon Suarez-Rodriguez , Roman Jacome , Romario Gualdron-Hurtado , Ana Mantilla-Dulcey , Henry Arguello

In this work, we address the limitations of denoising diffusion models (DDMs) in image restoration tasks, particularly the shape and color distortions that can compromise image quality. While DDMs have demonstrated a promising performance…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Xinlong Cheng , Tiantian Cao , Guoan Cheng , Bangxuan Huang , Xinghan Tian , Ye Wang , Xiaoyu He , Weixin Li , Tianfan Xue , Xuan Dong

Diffusion models have recently gained traction as a powerful class of deep generative priors, excelling in a wide range of image restoration tasks due to their exceptional ability to model data distributions. To solve image restoration…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Xiang Li , Soo Min Kwon , Shijun Liang , Ismail R. Alkhouri , Saiprasad Ravishankar , Qing Qu

Denoising diffusion models are a popular class of generative models providing state-of-the-art results in many domains. One adds gradually noise to data using a diffusion to transform the data distribution into a Gaussian distribution.…

Machine Learning · Computer Science 2023-08-21 Francisco Vargas , Will Grathwohl , Arnaud Doucet

Diffusion-based generative models employ stochastic differential equations (SDEs) and their equivalent probability flow ordinary differential equations (ODEs) to establish a smooth transformation between complex high-dimensional data…

Machine Learning · Computer Science 2025-12-12 Defang Chen , Zhenyu Zhou , Can Wang , Siwei Lyu

Complex systems with intricate causal dependencies challenge accurate prediction. Effective modeling requires precise physical process representation, integration of interdependent factors, and incorporation of multi-resolution…

Machine Learning · Computer Science 2025-04-08 Xuechun Li , Shan Gao , Susu Xu

This paper introduces a statistical treatment of inverse problems constrained by models with stochastic terms. The solution of the forward problem is given by a distribution represented numerically by an ensemble of simulations. The goal is…

Optimization and Control · Mathematics 2019-04-17 Emil M. Constantinescu , Noemi Petra , Julie Bessac , Cosmin G. Petra

Though the background is an important signal for image classification, over reliance on it can lead to incorrect predictions when spurious correlations between foreground and background are broken at test time. Training on a dataset where…

Computer Vision and Pattern Recognition · Computer Science 2022-11-21 Priyatham Kattakinda , Alexander Levine , Soheil Feizi

There is a growing literature adopting a stochastic optimal control (SOC) perspective to fine-tune diffusion models and related generative policies. A prominent class of methods, known as iterative diffusion optimization, solves the SOC…

Optimization and Control · Mathematics 2026-03-24 Yuhang Mei , Amirhossein Taghvaei

Diffusion models have shown strong performances in solving inverse problems through posterior sampling while they suffer from errors during earlier steps. To mitigate this issue, several Decoupled Posterior Sampling methods have been…

Machine Learning · Computer Science 2025-04-15 Zhi Qi , Shihong Yuan , Yulin Yuan , Linling Kuang , Yoshiyuki Kabashima , Xiangming Meng

Diffusion models have gained attention for their ability to represent complex distributions and incorporate uncertainty, making them ideal for robust predictions in the presence of noisy or incomplete data. In this study, we develop and…

Machine Learning · Computer Science 2024-11-05 Yilin Zhuang , Sibo Cheng , Karthik Duraisamy

Score-based generative models (SGMs) have recently emerged as a promising class of generative models. However, a fundamental limitation is that their inference is very slow due to a need for many (e.g., 2000) iterations of sequential…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Hengyuan Ma , Li Zhang , Xiatian Zhu , Jianfeng Feng

We explain how to use diffusion models to learn inverse renormalization group flows of statistical and quantum field theories. Diffusion models are a class of machine learning models which have been used to generate samples from complex…

High Energy Physics - Theory · Physics 2023-09-07 Jordan Cotler , Semon Rezchikov

Generating graph-structured data requires learning the underlying distribution of graphs. Yet, this is a challenging problem, and the previous graph generative methods either fail to capture the permutation-invariance property of graphs or…

Machine Learning · Computer Science 2022-06-16 Jaehyeong Jo , Seul Lee , Sung Ju Hwang

This work explores the theoretical and practical foundations of denoising diffusion probabilistic models (DDPMs) and score-based generative models, which leverage stochastic processes and Brownian motion to model complex data distributions.…

Machine Learning · Computer Science 2024-12-30 Jathin Korrapati , Tanish Baranwal , Rahul Shah
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