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The study of molecular impurities in $para$-hydrogen ($p$H$\rm_2$) clusters is key to push forward our understanding of intra- and intermolecular interactions including their impact on the superfluid response of this bosonic quantum…

Chemical Physics · Physics 2022-09-07 Laura Durán Caballero , Christoph Schran , Fabien Brieuc , Dominik Marx

Hydrogen atom transfer (HAT) reactions are essential in many biological processes, such as radical migration in damaged proteins, but their mechanistic pathways remain incompletely understood. Simulating HAT is challenging due to the need…

Machine Learning · Computer Science 2025-11-25 Marlen Neubert , Patrick Reiser , Frauke Gräter , Pascal Friederich

The most essential concept in concurrent multiscale methods involving atomistic-continuum coupling is how to define the relation between atomistic and continuum regions. A well-known coupling method that has been frequently employed in…

Mesoscale and Nanoscale Physics · Physics 2022-07-27 Pouya Towhidi , Manouchehr Salehi

Asymmetric Tensor PCA (ATPCA) is a prototypical model for studying the trade-offs between sample complexity, computation, and memory. Existing algorithms for this problem typically require at least…

Machine Learning · Computer Science 2026-04-14 Shihong Ding , Weicheng Lin , Cong Fang

Quantum computational chemistry holds great promise for simulating molecular systems more efficiently than classical methods by leveraging quantum bits to represent molecular wavefunctions. However, current implementations face significant…

Quantum Physics · Physics 2025-09-10 Weitang Li , Shi-Xin Zhang , Zirui Sheng , Cunxi Gong , Jianpeng Chen , Zhigang Shuai

Extracting information efficiently from quantum systems is a major component of quantum information processing tasks. Randomized measurements, or classical shadows, enable predicting many properties of arbitrary quantum states using few…

Principal component analysis (PCA) is a widely used dimension reduction technique in machine learning and multivariate statistics. To improve the interpretability of PCA, various approaches to obtain sparse principal direction loadings have…

Data Structures and Algorithms · Computer Science 2021-06-07 Agniva Chowdhury , Petros Drineas , David P. Woodruff , Samson Zhou

High-pressure polyhydrides are leading contenders for room temperature superconductivity. The next frontier lies in stabilizing them at ambient pressure, which would allow their practical applications. In this first-principles computational…

Superconductivity · Physics 2026-05-18 Đorđe Dangić , Manex Alkorta , Yuewen Fang , Ion Errea

Quantum chemistry provides key applications for near-term quantum computing, but these are greatly complicated by the presence of noise. In this work we present an efficient ansatz for the computation of two-electron atoms and molecules…

Quantum Physics · Physics 2020-04-23 Scott E. Smart , David A. Mazziotti

We present a new method for computing the lowest few eigenvalues and the corresponding eigenvectors of a nuclear many-body Hamiltonian represented in a truncated configuration interaction subspace, i.e., the no-core shell model (NCSM). The…

Computational Physics · Physics 2024-07-16 Dong Min Roh , Esmond Ng , Chao Yang , Dean Lee , Pieter Maris , James P. Vary

In the framework of density functional theory (DFT) simulations of molecules and materials, anharmonic terms of the potential energy surface are commonly computed numerically, with an associated cost that rapidly increases with the size of…

Materials Science · Physics 2025-03-17 Davide Mitoli , Jefferson Maul , Alessandro Erba

In recent years, machine learning models have been increasingly applied to spectroscopic datasets for chemical and biomedical analysis. For their successful adoption, particularly in clinical and safety-critical settings, professionals and…

Principal component analysis (PCA) is a key tool in the field of data dimensionality reduction. However, some applications involve heterogeneous data that vary in quality due to noise characteristics associated with each data sample.…

Machine Learning · Statistics 2026-03-18 Javier Salazar Cavazos , Jeffrey A. Fessler , Laura Balzano

The interaction of condensed phase systems with external electric fields is crucial in myriad processes in nature and technology ranging from the field-directed motion of cells (galvanotaxis), to energy storage and conversion systems…

Chemical Physics · Physics 2024-09-25 Kit Joll , Philipp Schienbein , Kevin M. Rosso , Jochen Blumberger

Ultrashort laser pulses on the attosecond timescale are typically achieved via high-order harmonic generation (HHG), a nonlinear process in which atoms interact with intense light fields to emit a broad spectrum of harmonics. HHG is…

Quantum Physics · Physics 2026-05-06 Anne Weber

Accurate crystal structure prediction (CSP) requires accounting for finite-temperature and nuclear quantum effects, yet first-principles evaluation of the free energy surface (FES) remains prohibitive for high-throughput searches. We…

Materials Science · Physics 2026-04-23 Xiaoyang Wang , Yinan Wang , Wenbo Zhao , Hanyu Liu , Hao Xie , Lei Wang , Han Wang

The declining synchronous inertia in power systems undergoing the energy transition increases the sensitivity of system frequency to generation and interconnector disturbances, making accurate frequency risk quantification increasingly…

Systems and Control · Electrical Eng. & Systems 2026-04-09 Sewedo Todowede

Metal-organic frameworks show both fundamental interest and great promise for applications in adsorption-based technologies, such as the separation and storage of gases. The flexibility and complexity of the molecular scaffold poses a…

Chemical accuracy serves as an important metric for assessing the effectiveness of the numerical method in Kohn--Sham density functional theory. It is found that to achieve chemical accuracy, not only the Kohn--Sham wavefunctions but also…

Computational Physics · Physics 2023-10-25 Yang Kuang , Yedan Shen , Guanghui Hu

Under extreme operating conditions, characterized by high particle multiplicity and heavily overlapping shower energy deposits, classical particle flow algorithms encounter pronounced limitations in resolution, efficiency, and accuracy. To…

Instrumentation and Detectors · Physics 2025-05-13 Yu Wang , Yangguang Zhang , Shengxiang Lin , Xingyi Zhang , Han Zhang