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We report an actuation/detection scheme with a top-down nano-electromechanical system for frequency shift-based sensing applications with outstanding performance. It relies on electrostatic actuation and piezoresistive nanowire gauges for…

Atomically thin layers of two-dimensional (2D) materials such as graphene, MoS2 and h-BN have immense potential as sensors and electronic devices thanks to their highly desirable electronic, mechanical, optical and heat transport…

Mesoscale and Nanoscale Physics · Physics 2015-09-03 Nicholas D. Kay , Peter D. Tovee , Benjamin J. Robinson , Konstantin S. Novoselov , Oleg V. Kolosov

Mass spectrometry provides a high-throughput way to identify proteins in biological samples. In a typical experiment, proteins in a sample are first broken into their constituent peptides. The resulting mixture of peptides is then subjected…

Applications · Statistics 2010-11-10 Qunhua Li , Michael J. MacCoss , Matthew Stephens

Label-free imaging of rapidly moving, sub-diffraction sized structures has important applications in both biology and material science, as it removes the limitations associated with fluorescence tagging. However, unlabeled nanoscale…

Molecular fingerprinting through absorption spectroscopy is a powerful analytical method. Wide spectral ranges are explored with Doppler-limited resolution. Fast data acquisition, accurate measurements of frequency, intensity, and line…

Optics · Physics 2008-08-20 Julien Mandon , Guy Guelachvili , Nathalie Picqué

To fully understand, analyze, and determine the behavior of dynamical systems, it is crucial to identify their intrinsic modal coordinates. In nonlinear dynamical systems, this task is challenging as the modal transformation based on the…

Machine Learning · Computer Science 2025-03-13 Abdolvahhab Rostamijavanani , Shanwu Li , Yongchao Yang

Human fingerprints serve as one unique and powerful characteristic for each person, from which policemen can recognize the identity. Similar to humans, many natural bodies and intrinsic mechanical qualities can also be uniquely identified…

Machine Learning · Computer Science 2024-03-25 Yongchao Chen

Rapid, non-destructive characterization of molecular level chemistry for organic matter (OM) is experimentally challenging. Raman spectroscopy is one of the most widely used techniques for non-destructive chemical characterization, although…

Materials Science · Physics 2016-02-08 Yun Liu , Nicola Ferralis , L. Taras Bryndzia , Jeffrey C. Grossman

Ultrashort time-domain spectroscopy and field-resolved spectroscopy of molecular fingerprints are gold standards for detecting samples' constituents and internal dynamics. However, they are hindered by the Nyquist criterion, leading to…

Finding efficient means of fingerprinting microstructural information is a critical step towards harnessing data-centric machine learning approaches. A statistical framework is systematically developed for compressed characterisation of a…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Michael D. White , Alexander Tarakanov , Christopher P. Race , Philip J. Withers , Kody J. H. Law

The identification and property prediction of chemical molecules is of central importance in the advancement of drug discovery and material science, where the tandem mass spectrometry technology gives valuable fragmentation cues in the form…

Artificial Intelligence · Computer Science 2026-04-14 Yunhua Zhong , Yixuan Tang , Yifan Li , Jie Yang , Pan Liu , Jun Xia

Nuclear magnetic resonance (NMR) spectroscopy provides unparalleled access to molecular structure and dynamics but is traditionally limited by weak signal strength, requiring large sample volumes and high magnetic fields. Here, we…

Applied Physics · Physics 2026-04-29 Dileep Singh , Riley W. Hooper , Christoph Findler , Utsab Banerjee , Dominik B. Bucher

Conventional nuclear magnetic resonance (NMR) spectroscopy relies on acquiring signal from a macroscopic ensemble of molecules to gain information about molecular structure and dynamics. Transferring this technique to nanoscale sample sizes…

Mesoscale and Nanoscale Physics · Physics 2019-02-06 Jeffrey Holzgrafe , Qiushi Gu , Jan Beitner , Dhiren Kara , Helena S. Knowles , Mete Atatüre

Infrared spectroscopy is the technique of choice for chemical identification of biomolecules through their vibrational fingerprints. However, infrared light interacts poorly with nanometric size molecules. Here, we exploit the unique…

Deep neural networks (DNNs) have achieved remarkable success in radio frequency (RF) fingerprinting for wireless device authentication. However, their practical deployment faces two major limitations: domain shift, where models trained in…

Cryptography and Security · Computer Science 2026-02-04 Tianya Zhao , Junqing Zhang , Haowen Xu , Xiaoyan Sun , Jun Dai , Xuyu Wang

In the 21st century, biosensors have gathered much wider attention than ever before, irrespective of the technology that promises to bring them forward. With the recent COVID-19 outbreak, the concern and efforts to restore global health and…

Medical Physics · Physics 2023-02-14 Vinayak Pachkawade

Scanning Electron Microscopy (SEM) is indispensable in modern materials science, enabling high-resolution imaging across a wide range of structural, chemical, and functional investigations. However, SEM imaging remains constrained by…

The near infrared (NIR) region of the electromagnetic spectrum contains valuable information about vibrational overtone and combination modes. Additionally, fluorophores that emit in the NIR are desired because this spectral range falls…

This review presents the fundamentals of Flicker-Noise Spectroscopy (FNS), a general phenomenological methodology in which the dynamics and structure of complex systems, characterized by nonlinear interactions, dissipation, and inertia, are…

Data Analysis, Statistics and Probability · Physics 2008-12-02 Serge F. Timashev , Yuriy S. Polyakov

Advanced geometrical nanometrology is critical for process control in semiconductor manufacturing, supporting applications in, e.g., photonic integrated circuits, nanoelectronics, and emerging quantum and optoelectronic technologies.…