English
Related papers

Related papers: An End-to-End Coding Scheme for DNA-Based Data Sto…

200 papers

In [1], the authors proposed a new model of DNA storage system that integrates all three steps of retrieval and introduced the concept of DNA-correcting codes, which guarantees that the output of the storage system can be decoded to the…

Information Theory · Computer Science 2023-11-17 Huawei Wu

DNA emerges as a promising medium for the exponential growth of digital data due to its density and durability. This study extends recent research by addressing the \emph{coverage depth problem} in practical scenarios, exploring optimal…

Information Theory · Computer Science 2024-02-01 Hadas Abraham , Rayn Gabrys , Eitan Yaakobi

Decoding sequences that stem from multiple transmissions of a codeword over an insertion, deletion, and substitution channel is a critical component of efficient deoxyribonucleic acid (DNA) data storage systems. In this paper, we consider a…

Information Theory · Computer Science 2020-10-30 Andreas Lenz , Issam Maarouf , Lorenz Welter , Antonia Wachter-Zeh , Eirik Rosnes , Alexandre Graell i Amat

DNA storage is a promising archival data storage solution to today's big data problem. A DNA storage system encodes and stores digital data with synthetic DNA sequences and decodes DNA sequences back to digital data via sequencing. For…

Emerging Technologies · Computer Science 2024-03-22 Yixun Wei , Wenlong Wang , Huibing Dong , Bingzhe Li , David Du

Although the expenses associated with DNA sequencing have been rapidly decreasing, the current cost of sequencing information stands at roughly $120/GB, which is dramatically more expensive than reading from existing archival storage…

Discrete Mathematics · Computer Science 2023-11-30 Daniella Bar-Lev , Omer Sabary , Ryan Gabrys , Eitan Yaakobi

Due to their sequential nature, traditional DNA synthesis methods are expensive in terms of time and resources. They also fabricate multiple copies of the same strand, introducing redundancy. This redundancy can be leveraged to enhance the…

Information Theory · Computer Science 2025-10-29 Frederik Walter , Yonatan Yehezkeally

As DNA data storage moves closer to practical deployment, minimizing sequencing coverage depth is essential to reduce both operational costs and retrieval latency. This paper addresses the recently studied Random Access Problem, which…

Information Theory · Computer Science 2026-01-13 Chen Wang , Eitan Yaakobi

Digital information can be encoded in the building-block sequence of macromolecules, such as RNA and single-stranded DNA. Methods of "writing" and "reading" macromolecular strands are currently available, but they are slow and expensive. In…

Emerging Technologies · Computer Science 2017-09-14 Pramod K. Khulbe , Raphael Gruener , Masud Mansuripur

Recently, DNA storage has surfaced as a promising alternative for data storage, presenting notable benefits in terms of storage capacity, cost-effectiveness in maintenance, and the capability for parallel replication. Mathematically, the…

Information Theory · Computer Science 2024-01-31 Yi Lu , Yun Ma , Chenghao Li , Xin Zhang , Guangxiang Si

DNA based storage systems received attention by many researchers. This includes archival and re-writable random access DNA based storage systems. In this work, we have developed an efficient technique to encode the data into DNA sequence by…

Information Theory · Computer Science 2016-04-25 Dixita Limbachiya , Vijay Dhameliya , Madhav Khakhar , Manish K Gupta

Owing to its immense storage density and durability, DNA has emerged as a promising storage medium. However, due to technological constraints, data can only be written onto many short DNA molecules called data blocks that are stored in an…

Information Theory · Computer Science 2024-03-26 Shubhransh Singhvi , Charchit Gupta , Avital Boruchovsky , Yuval Goldberg , Han Mao Kiah , Eitan Yaakobi

We consider the problem of assembling a sequence based on a collection of its substrings observed through a noisy channel. The mathematical basis of the problem is the construction and design of sequences that may be discriminated based on…

Information Theory · Computer Science 2015-11-04 Han Mao Kiah , Gregory J. Puleo , Olgica Milenkovic

We investigate the capacity of noisy frequency-based channels, motivated by DNA data storage in the short-molecule regime, where information is encoded in the frequency of items types rather than their order. The channel output is a…

Information Theory · Computer Science 2026-01-16 Yuval Gerzon , Ilan Shomorony , Nir Weinberger

Motivated by DNA-based storage applications, we study the problem of reconstructing a coded sequence from multiple traces. We consider the model where the traces are outputs of independent deletion channels, where each channel deletes each…

Information Theory · Computer Science 2022-07-13 Serge Kas Hanna

We initiate the study of DNA-based distributed storage systems, where information is encoded across multiple DNA data storage containers to achieve robustness against container failures. In this setting, data are distributed over $M$…

Information Theory · Computer Science 2026-02-10 Adi Levy , Roni Con , Eitan Yaakobi , Han Mao Kiah

A new family of codes, called clustering-correcting codes, is presented in this paper. This family of codes is motivated by the special structure of data that is stored in DNA-based storage systems. The data stored in these systems has the…

Information Theory · Computer Science 2019-03-12 Tal Shinkar , Eitan Yaakobi , Andreas Lenz , Antonia Wachter-Zeh

Storing digital data in synthetic DNA faces challenges in ensuring data reliability in the presence of edit errors--deletions, insertions, and substitutions--that occur randomly during various stages of the storage process. Current…

Information Theory · Computer Science 2025-09-11 Serge Kas Hanna

Over the past years, the ever-growing trend on data storage demand, more specifically for "cold" data (rarely accessed data), has motivated research for alternative systems of data storage. Because of its biochemical characteristics,…

Machine Learning · Computer Science 2022-03-21 Xavier Pic , Marc Antonini

We propose a new coding scheme, called the delayed coding (DC) scheme, for channels with insertion, deletion, and substitution (IDS) errors. The proposed scheme employs delayed encoding and non-iterative detection and decoding strategies to…

Information Theory · Computer Science 2022-05-25 Ryo Shibata , Hiroyuki Yashima

Motivated by DNA-based data storage, we investigate a system where digital information is stored in an unordered set of several vectors over a finite alphabet. Each vector begins with a unique index that represents its position in the whole…

Information Theory · Computer Science 2019-01-23 Andreas Lenz , Paul H. Siegel , Antonia Wachter-Zeh , Eitan Yaakobi