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Aging clocks aim to estimate biological age, a measure of physiological state distinct from chronological age, from observable biomarkers, and are widely used for health assessment and disease analysis. DNA methylation is a particularly…

Machine Learning · Computer Science 2026-05-11 Qing Qing , Xikun Zhang , Zhongyuan Zhang , Jiarui Liu , Xingtong Yu , Xiaotao Shen , Ziqi Xu , Qixin Zhang , Zhe Wang , Renqiang Luo

Convolutional neural networks (CNNs) based approaches for semantic alignment and object landmark detection have improved their performance significantly. Current efforts for the two tasks focus on addressing the lack of massive training…

Computer Vision and Pattern Recognition · Computer Science 2019-10-03 Sangryul Jeon , Dongbo Min , Seungryong Kim , Kwanghoon Sohn

Landmark detection plays a crucial role in medical imaging applications such as disease diagnosis, bone age estimation, and therapy planning. However, training models for detecting multiple landmarks simultaneously often encounters the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Xu He , Zhen Huang , Qingsong Yao , Xiaoqian Zhou , S. Kevin Zhou

Facial landmark detection plays an important role for the similarity analysis in artworks to compare portraits of the same or similar artists. With facial landmarks, portraits of different genres, such as paintings and prints, can be…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Aline Sindel , Andreas Maier , Vincent Christlein

Fast and accurate anatomical landmark detection can benefit many medical image analysis methods. Here, we propose a method to automatically detect anatomical landmarks in medical images. Automatic landmark detection is performed with a…

Computer Vision and Pattern Recognition · Computer Science 2018-04-16 Julia M. H. Noothout , Bob D. de Vos , Jelmer M. Wolterink , Tim Leiner , Ivana Išgum

Accurate identification of late-life depression (LLD) using structural brain MRI is essential for monitoring disease progression and facilitating timely intervention. However, existing learning-based approaches for LLD detection are often…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Yuzhen Gao , Qianqian Wang , Yongheng Sun , Cui Wang , Yongquan Liang , Mingxia Liu

In current biological and medical research, statistical shape modeling (SSM) provides an essential framework for the characterization of anatomy/morphology. Such analysis is often driven by the identification of a relatively small number of…

Computer Vision and Pattern Recognition · Computer Science 2021-11-16 Riddhish Bhalodia , Shireen Elhabian , Ladislav Kavan , Ross Whitaker

Graph-based change point detection (CPD) play an irreplaceable role in discovering anomalous graphs in the time-varying network. While several techniques have been proposed to detect change points by identifying whether there is a…

Social and Information Networks · Computer Science 2022-12-20 Yongshun Gong , Xue Dong , Jian Zhang , Meng Chen

Reliable 3D-2D alignment between intraoral scan (IOS) models and lateral cephalometric radiographs is critical for orthodontic diagnosis, yet conventional intensity-driven registration methods struggle under real clinical conditions, where…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Yiyi Miao , Taoyu Wu , Ji Jiang , Tong Chen , Zhe Tang , Zhengyong Jiang , Angelos Stefanidis , Limin Yu , Jionglong Su

3D landmark detection is a critical task in medical image analysis, and accurately detecting anatomical landmarks is essential for subsequent medical imaging tasks. However, mainstream deep learning methods in this field struggle to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Zhen Huang , Tao Tang , Ronghao Xu , Yangbo Wei , Wenkai Yang , Suhua Wang , Xiaoxin Sun , Han Li , Qingsong Yao

The ageing population trend is correlated with an increased prevalence of acquired cognitive impairments such as dementia. Although there is no cure for dementia, a timely diagnosis helps in obtaining necessary support and appropriate…

Computer Vision and Pattern Recognition · Computer Science 2021-01-06 Xing Liang , Anastassia Angelopoulou , Epaminondas Kapetanios , Bencie Woll , Reda Al-batat , Tyron Woolfe

In this paper, we examine 3 important issues in the practical use of state-of-the-art facial landmark detectors and show how a combination of specific architectural modifications can directly improve their accuracy and temporal stability.…

Computer Vision and Pattern Recognition · Computer Science 2024-05-31 Prashanth Chandran , Gaspard Zoss , Paulo Gotardo , Derek Bradley

Accurate facial landmarks are essential prerequisites for many tasks related to human faces. In this paper, an accurate facial landmark detector is proposed based on cascaded transformers. We formulate facial landmark detection as a…

Computer Vision and Pattern Recognition · Computer Science 2022-08-24 Hui Li , Zidong Guo , Seon-Min Rhee , Seungju Han , Jae-Joon Han

With the increasing popularity of convolutional neural networks (CNNs), recent works on face-based age estimation employ these networks as the backbone. However, state-of-the-art CNN-based methods treat each facial region equally, thus…

Computer Vision and Pattern Recognition · Computer Science 2022-02-09 Haoyi Wang , Victor Sanchez , Chang-Tsun Li

Over half of US adults with Alzheimer disease and related dementias remain undiagnosed, and speech-based screening offers a scalable detection approach. We compared large language model adaptation strategies for dementia detection using the…

We lay the groundwork for research in the algorithmic comprehension of infant faces, in anticipation of applications from healthcare to psychology, especially in the early prediction of developmental disorders. Specifically, we introduce…

Computer Vision and Pattern Recognition · Computer Science 2022-05-30 Michael Wan , Shaotong Zhu , Lingfei Luan , Gulati Prateek , Xiaofei Huang , Rebecca Schwartz-Mette , Marie Hayes , Emily Zimmerman , Sarah Ostadabbas

Anatomical landmark detection (ALD) from a medical image is crucial for a wide array of clinical applications. While existing methods achieve quite some success in ALD, they often struggle to balance global context with computational…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Xiaoqian Zhou , Zhen Huang , Heqin Zhu , Qingsong Yao , S. Kevin Zhou

Convolutional Neural Networks (CNN) have been applied to age-related research as the core framework. Although faces are composed of numerous facial attributes, most works with CNNs still consider a face as a typical object and do not pay…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Haoyi Wang , Xingjie Wei , Victor Sanchez , Chang-Tsun Li

Facial landmark detection, or face alignment, is a fundamental task that has been extensively studied. In this paper, we investigate a new perspective of facial landmark detection and demonstrate it leads to further notable improvement.…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Shengju Qian , Keqiang Sun , Wayne Wu , Chen Qian , Jiaya Jia

Radiographic images are a cornerstone of medical diagnostics in orthopaedics, with anatomical landmark detection serving as a crucial intermediate step for information extraction. General-purpose foundational segmentation models, such as…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Ekaterina Stansfield , Jennifer A. Mitterer , Abdulrahman Altahhan