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Quantitative susceptibility mapping (QSM) has been increasingly applied in longitudinal studies of neurodegenerative diseases and aging to assess temporal alterations in brain iron and myelin. The accuracy of such investigations depends on…

Quantitative Methods · Quantitative Biology 2026-05-05 Jiye Kim , Hwihun Jeong , Taechang Kim , Eunseon Jeong , Jinhee Jang , Yangsean Choi , Jongho Lee

Background: Quantitative susceptibility mapping (QSM) of the brain is an advanced MRI technique for assessing tissue characteristics based on magnetic susceptibility, which varies with the composition of the tissue, such as iron, calcium,…

Deep neural networks have demonstrated great potential in solving dipole inversion for Quantitative Susceptibility Mapping (QSM). However, the performances of most existing deep learning methods drastically degrade with mismatched sequence…

Medical Physics · Physics 2022-11-28 Zhuang Xiong , Yang Gao , Feng Liu , Hongfu Sun

A learning-based posterior distribution estimation method, Probabilistic Dipole Inversion (PDI), is proposed to solve the quantitative susceptibility mapping (QSM) inverse problem in MRI with uncertainty estimation. In PDI, a deep…

Image and Video Processing · Electrical Eng. & Systems 2021-03-16 Jinwei Zhang , Hang Zhang , Mert Sabuncu , Pascal Spincemaille , Thanh Nguyen , Yi Wang

This article provides recommendations for implementing quantitative susceptibility mapping (QSM) for clinical brain research. It is a consensus of the ISMRM Electro-Magnetic Tissue Properties Study Group. While QSM technical development…

Recently, deep neural network-powered quantitative susceptibility mapping (QSM), QSMnet, successfully performed ill conditioned dipole inversion in QSM and generated high-quality susceptibility maps. In this paper, the network, which was…

Image and Video Processing · Electrical Eng. & Systems 2019-10-15 Woojin Jung , Jaeyeon Yoon , Joon Yul Choi , Jae Myung Kim , Yoonho Nam , Eung Yeop Kim , Jongho Lee

Purpose: Quantitative Susceptibility Mapping (QSM) reconstruction is a challenging inverse problem driven by poor conditioning of the field to susceptibility transformation. State-of-art QSM reconstruction methods either suffer from image…

Medical Physics · Physics 2019-03-14 Juan Liu , Andrew S. Nencka , L. Tugan Muftuler , Brad Swearingen , Robin Karr , Kevin M. Koch

Quantitative susceptibility mapping (QSM) is a MRI technique that estimates tissue magnetic susceptibility. The generation of QSM requires solving a challenging ill-posed field-to-source inversion problem. Recently, several deep learning…

Medical Physics · Physics 2022-06-28 Juan Liu , Kevin Koch

Deep learning based Quantitative Susceptibility Mapping (QSM) has shown great potential in recent years, obtaining similar results to established non-learning approaches. Many current deep learning approaches are not data consistent,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-31 Francesco Cognolato , Kieran O'Brien , Jin Jin , Simon Robinson , Frederik B. Laun , Markus Barth , Steffen Bollmann

Purpose: For quantitative susceptibility mapping (QSM), the lack of ground-truth in clinical settings makes it challenging to determine suitable parameters for the dipole inversion. We propose a probabilistic Bayesian approach for QSM with…

Image and Video Processing · Electrical Eng. & Systems 2023-06-01 Shuai Huang , James J. Lah , Jason W. Allen , Deqiang Qiu

Quantitative susceptibility mapping (QSM) aims to visualize the three dimensional susceptibility distribution by solving the field-to-source inverse problem using the phase data in magnetic resonance signal. However, the inverse problem is…

Numerical Analysis · Mathematics 2018-12-31 Chenglong Bao , Jae Kyu Choi , Bin Dong

Quantitative susceptibility mapping (QSM) utilizes MRI phase information to estimate tissue magnetic susceptibility. The generation of QSM requires solving ill-posed background field removal (BFR) and field-to-source inversion problems.…

Image and Video Processing · Electrical Eng. & Systems 2020-08-17 Juan Liu , Kevin M Koch

Quantitative susceptibility mapping (QSM) is a post-processing technique for deriving tissue magnetic susceptibility distribution from MRI phase measurements. Deep learning (DL) algorithms hold great potential for solving the ill-posed QSM…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Yang Gao , Zhuang Xiong , Shanshan Shan , Yin Liu , Pengfei Rong , Min Li , Alan H Wilman , G. Bruce Pike , Feng Liu , Hongfu Sun

A learning-based posterior distribution estimation method, Probabilistic Dipole Inversion (PDI), is proposed to solve quantitative susceptibility mapping (QSM) inverse problem in MRI with uncertainty estimation. A deep convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2020-04-28 Jinwei Zhang , Hang Zhang , Mert Sabuncu , Pascal Spincemaille , Thanh Nguyen , Yi Wang

Quantitative susceptibility mapping (QSM) inevitably suffers from streaking artifacts caused by zeros on the conical surface of the dipole kernel in k-space. This work proposes a novel and accurate QSM reconstruction method based on a…

Computer Vision and Pattern Recognition · Computer Science 2019-10-16 Hyun-Seo Ahn , Sung-Hong Park , Jong Chul Ye

Magnetic resonance imaging (MRI) offers superior soft tissue contrast and is widely used in biomedicine. However, conventional MRI is not quantitative, which presents a bottleneck in image analysis and digital healthcare. Typically,…

We propose Nonlinear Dipole Inversion (NDI) for high-quality Quantitative Susceptibility Mapping (QSM) without regularization tuning, while matching the image quality of state-of-the-art reconstruction techniques. In addition to avoiding…

Image and Video Processing · Electrical Eng. & Systems 2019-10-01 Daniel Polak , Itthi Chatnuntawech , Jaeyeon Yoon , Siddharth Srinivasan Iyer , Jongho Lee , Peter Bachert , Elfar Adalsteinsson , Kawin Setsompop , Berkin Bilgic

Quantitative susceptibility mapping (QSM) provides a valuable tool for quantifying susceptibility distributions in human brains; however, two types of opposing susceptibility sources (i.e., paramagnetic and diamagnetic), may coexist in a…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Min Li , Chen Chen , Zhenghao Li , Yin Liu , Shanshan Shan , Peng Wu , Pengfei Rong , Feng Liu , G. Bruce Pike , Alan H. Wilman , Hongfu Sun , Yang Gao

While deep neural networks (NN) significantly advance image compressed sensing (CS) by improving reconstruction quality, the necessity of training current CS NNs from scratch constrains their effectiveness and hampers rapid deployment.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Bin Chen , Zhenyu Zhang , Weiqi Li , Chen Zhao , Jiwen Yu , Shijie Zhao , Jie Chen , Jian Zhang

Quantitative MRI (qMRI) offers significant advantages over weighted images by providing objective parameters related to tissue properties. Deep learning-based methods have demonstrated effectiveness in estimating quantitative maps from…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Shishuai Wang , Hua Ma , Juan A. Hernandez-Tamames , Stefan Klein , Dirk H. J. Poot