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Equipping Large Language Models (LLMs) with external tools enables them to solve complex real-world problems. However, the robustness of existing methods remains a critical challenge when confronting novel or evolving tools. Existing…

Software Engineering · Computer Science 2026-01-21 Xingjie Gao , Pengcheng Huang , Zhenghao Liu , Yukun Yan , Shuo Wang , Zulong Chen , Chen Qian , Ge Yu , Yu Gu

The disruptive technology provided by large-scale pre-trained language models (LLMs) such as ChatGPT or GPT-4 has received significant attention in several application domains, often with an emphasis on high-level opportunities and…

Human-Computer Interaction · Computer Science 2023-06-27 Philippe J. Giabbanelli

Online health resources and large language models (LLMs) are increasingly used as a first point of contact for medical decision-making, yet their reliability in healthcare remains limited by low accuracy, lack of transparency, and…

Artificial Intelligence · Computer Science 2026-04-22 Yujia Liu , Sophia Yu , Hongyue Jin , Jessica Wen , Alexander Qian , Terrence Lee , Mattheus Ramsis , Gi Won Choi , Lianhui Qin , Xin Liu , Edward J. Wang

There is increasing interest in the application large language models (LLMs) to the medical field, in part because of their impressive performance on medical exam questions. While promising, exam questions do not reflect the complexity of…

The emergence of multimodal LLM-based agents (MLAs) has transformed interaction paradigms by seamlessly integrating vision, language, action and dynamic environments, enabling unprecedented autonomous capabilities across GUI applications…

Artificial Intelligence · Computer Science 2025-06-03 Xiao Yang , Jiawei Chen , Jun Luo , Zhengwei Fang , Yinpeng Dong , Hang Su , Jun Zhu

Large language models (LLMs) and LLM-based agents are increasingly deployed as assistants in planning and decision making, yet most existing systems are implicitly optimized for a single-principal interaction paradigm, in which the model is…

Computation and Language · Computer Science 2026-04-29 Shu Yang , Shenzhe Zhu , Hao Zhu , José Ramón Enríquez , Di Wang , Alex Pentland , Michiel A. Bakker , Jiaxin Pei

In recent years, AI has demonstrated remarkable capabilities in simulating human behaviors, particularly those implemented with large language models (LLMs). However, due to the lack of systematic evaluation of LLMs' simulated behaviors,…

Computation and Language · Computer Science 2024-06-18 Yang Xiao , Yi Cheng , Jinlan Fu , Jiashuo Wang , Wenjie Li , Pengfei Liu

Large Language Models (LLMs) have shown capabilities close to human performance in various analytical tasks, leading researchers to use them for time and labor-intensive analyses. However, their capability to handle highly specialized and…

Computation and Language · Computer Science 2024-10-08 Alexander S. Choi , Syeda Sabrina Akter , JP Singh , Antonios Anastasopoulos

Large Language Models (LLMs) are increasingly employed for simulating human behaviors across diverse domains. However, our position is that current LLM-based human simulations remain insufficiently reliable, as evidenced by significant…

Computation and Language · Computer Science 2025-12-02 Qian Wang , Jiaying Wu , Zichen Jiang , Zhenheng Tang , Bingqiao Luo , Nuo Chen , Wei Chen , Bingsheng He

In an ideal design pipeline, user interface (UI) design is intertwined with user research to validate decisions, yet studies are often resource-constrained during early exploration. Recent advances in multimodal large language models…

The proliferation of Large Language Models (LLMs) in high-stakes applications such as medical (self-)diagnosis and preliminary triage raises significant ethical and practical concerns about the effectiveness, appropriateness, and possible…

Computers and Society · Computer Science 2025-06-18 Bonam Mingole , Aditya Majumdar , Firdaus Ahmed Choudhury , Jennifer L. Kraschnewski , Shyam S. Sundar , Amulya Yadav

The integration of Large Language Models (LLMs) into medical applications has sparked widespread interest across the healthcare industry, from drug discovery and development to clinical decision support, assisting telemedicine, medical…

Computation and Language · Computer Science 2024-12-03 Zifeng Wang , Hanyin Wang , Benjamin Danek , Ying Li , Christina Mack , Hoifung Poon , Yajuan Wang , Pranav Rajpurkar , Jimeng Sun

The widespread adoption of Large Language Models (LLMs) and LLM-powered agents in multi-user settings underscores the need for reliable, usable methods to accommodate diverse preferences and resolve conflicting directives. Drawing on…

Human-Computer Interaction · Computer Science 2025-03-20 Christine Lee , Jihye Choi , Bilge Mutlu

Empowering chatbots in the field of mental health is receiving increasing amount of attention, while there still lacks exploration in developing and evaluating chatbots in psychiatric outpatient scenarios. In this work, we focus on…

Computation and Language · Computer Science 2023-05-24 Siyuan Chen , Mengyue Wu , Kenny Q. Zhu , Kunyao Lan , Zhiling Zhang , Lyuchun Cui

The proliferation of Large Language Models (LLMs) and Intelligent Virtual Agents acting as psychotherapists presents significant opportunities for expanding mental healthcare access. However, their deployment has also been linked to serious…

Computation and Language · Computer Science 2025-09-23 Ian Steenstra , Timothy W. Bickmore

Conversational recommender systems (CRS) enhance user experience through multi-turn interactions, yet evaluating CRS remains challenging. User simulators can provide comprehensive evaluations through interactions with CRS, but building…

Human-Computer Interaction · Computer Science 2025-08-01 Luyu Chen , Quanyu Dai , Zeyu Zhang , Xueyang Feng , Mingyu Zhang , Pengcheng Tang , Xu Chen , Yue Zhu , Zhenhua Dong

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

With the rapid development of artificial intelligence (AI), large language models (LLMs) have shown strong capabilities in natural language understanding, reasoning, and generation, attracting amounts of research interest in applying LLMs…

Artificial Intelligence · Computer Science 2024-07-30 Tongyue Shi , Jun Ma , Zihan Yu , Haowei Xu , Minqi Xiong , Meirong Xiao , Yilin Li , Huiying Zhao , Guilan Kong

Training medical personnel using standardized patients (SPs) remains a complex challenge, requiring extensive domain expertise and role-specific practice. Previous research on Large Language Model (LLM)-based SPs mostly focuses on improving…

Computation and Language · Computer Science 2025-06-10 Zhuoyun Du , Lujie Zheng , Renjun Hu , Yuyang Xu , Xiawei Li , Ying Sun , Wei Chen , Jian Wu , Haolei Cai , Haohao Ying

Large Language Models (LLMs) and causal learning each hold strong potential for clinical decision making (CDM). However, their synergy remains poorly understood, largely due to the lack of systematic benchmarks evaluating their integration…

Machine Learning · Computer Science 2025-11-14 Linna Wang , Zhixuan You , Qihui Zhang , Jiunan Wen , Ji Shi , Yimin Chen , Yusen Wang , Fanqi Ding , Ziliang Feng , Li Lu