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With the rapid development of deep learning, recent research on intelligent and interactive mobile applications (e.g., health monitoring, speech recognition) has attracted extensive attention. And these applications necessitate the mobile…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-10-26 Bowen Pang , Sicong Liu , Hongli Wang , Bin Guo , Yuzhan Wang , Hao Wang , Zhenli Sheng , Zhongyi Wang , Zhiwen Yu

Genome-wide association studies (GWASs) aim to detect genetic risk factors for complex human diseases by identifying disease-associated single-nucleotide polymorphisms (SNPs). The traditional SNP-wise approach along with multiple testing…

Methodology · Statistics 2019-09-25 Yan Xu , Li Xing , Jessica Su , Xuekui Zhang , Weiliang Qiu

Improved understanding of charge-transport in single molecules is essential for harnessing the potential of molecules e.g. as circuit components at the ultimate size limit. However, interpretation and analysis of the large, stochastic…

Mesoscale and Nanoscale Physics · Physics 2020-08-06 Nathan D. Bamberger , Jeffrey A. Ivie , Keshaba N. Parida , Dominic V. McGrath , Oliver L. A. Monti

Recent advances in generative models have highlighted the need for robust detectors capable of distinguishing real images from AI-generated images. While existing methods perform well on known generators, their performance often declines…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Kuo Shi , Jie Lu , Shanshan Ye , Guangquan Zhang , Zhen Fang

Simultaneous multislice (SMS) imaging is a powerful technique for accelerating magnetic resonance imaging (MRI) acquisitions. However, SMS reconstruction remains challenging due to complex signal interactions between and within the excited…

Image and Video Processing · Electrical Eng. & Systems 2025-12-16 Shoujin Huang , Guanxiong Luo , Yunlin Zhao , Yilong Liu , Yuwan Wang , Kexin Yang , Jingzhe Liu , Hua Guo , Min Wang , Lingyan Zhang , Mengye Lyu

Skeleton-based action recognition leverages human pose keypoints to categorize human actions, which shows superior generalization and interoperability compared to regular end-to-end action recognition. Existing solutions use RGB cameras to…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Shunyu Huang , Yunjiao Zhou , Jianfei Yang

Inspired by the effectiveness of genetic algorithms and the importance of synthesizability in molecular design, we present SynGA, a simple genetic algorithm that operates directly over synthesis routes. Our method features custom crossover…

Machine Learning · Computer Science 2026-03-03 Alston Lo , Connor W. Coley , Wojciech Matusik

Metagenome, a mixture of different genomes (as a rule, bacterial), represents a pattern, and the analysis of its composition is, currently, one of the challenging problems of bioinformatics. In the present study, the possibility of…

Quantitative Methods · Quantitative Biology 2016-11-04 Valery Kirzhner , Zeev Volkovich , Renata Avros , Katerina Korenblat

Genome sequence analysis, which examines the DNA sequences of organisms, drives advances in many critical medical and biotechnological fields. Given its importance and the exponentially growing volumes of genomic sequence data, there are…

Classical machine learning models such as deep neural networks are usually trained by using Stochastic Gradient Descent-based (SGD) algorithms. The classical SGD can be interpreted as a discretization of the stochastic gradient flow. In…

Optimization and Control · Mathematics 2023-10-03 Valentin Leplat , Daniil Merkulov , Aleksandr Katrutsa , Daniel Bershatsky , Olga Tsymboi , Ivan Oseledets

Generative models have received significant attention in recent years for materials science applications, particularly in the area of inverse design for materials discovery. However, these models are usually assessed based on newly…

Materials Science · Physics 2024-09-12 Adrian Xiao Bin Yong , Tianyu Su , Elif Ertekin

The prevalence of networked sensors and actuators in many real-world systems such as smart buildings, factories, power plants, and data centers generate substantial amounts of multivariate time series data for these systems. The rich sensor…

Machine Learning · Computer Science 2019-01-17 Dan Li , Dacheng Chen , Lei Shi , Baihong Jin , Jonathan Goh , See-Kiong Ng

Artificial intelligence (AI) is increasingly used in every stage of drug development. Continuing breakthroughs in AI-based methods for drug discovery require the creation, improvement, and refinement of drug discovery data. We posit a new…

Machine Learning · Computer Science 2024-05-08 Bing Hu , Ashish Saragadam , Anita Layton , Helen Chen

Masked Graph Auto-Encoder, a powerful graph self-supervised training paradigm, has recently shown superior performance in graph representation learning. Existing works typically rely on node contextual information to recover the masked…

Machine Learning · Computer Science 2025-08-15 Ziyu Zheng , Yaming Yang , Ziyu Guan , Wei Zhao , Weigang Lu

Identification of features is a critical task in microbiome studies that is complicated by the fact that microbial data are high dimensional and heterogeneous. Masked by the complexity of the data, the problem of separating signals from…

Methodology · Statistics 2020-09-18 Liangliang Zhang , Yushu Shi , Kim-Anh Do , Christine B. Peterson , Robert R. Jenq

Secondary contact between divergent populations or incipient species may result in the exchange and introgression of genomic material. We develop a simple DNA sequence measure, called Gmin, which is designed to identify genomic regions…

Populations and Evolution · Quantitative Biology 2017-02-08 Anthony J. Geneva , Sarah B. Kingan , Daniel Garrigan

Accurately predicting the survival rate of cancer patients is crucial for aiding clinicians in planning appropriate treatment, reducing cancer-related medical expenses, and significantly enhancing patients' quality of life. Multimodal…

Computer Vision and Pattern Recognition · Computer Science 2024-03-15 Liangrui Pan , Yijun Peng , Yan Li , Xiang Wang , Wenjuan Liu , Liwen Xu , Qingchun Liang , Shaoliang Peng

Accurate interpretation of electrocardiogram (ECG) signals is crucial for diagnosing cardiovascular diseases. Recent multimodal approaches that integrate ECGs with accompanying clinical reports show strong potential, but they still face two…

Artificial Intelligence · Computer Science 2026-02-25 Ziwei Niu , Hao Sun , Shujun Bian , Xihong Yang , Lanfen Lin , Yuxin Liu , Yueming Jin

Motivation: Most existing methods for DNA sequence analysis rely on accurate sequences or genotypes. However, in applications of the next-generation sequencing (NGS), accurate genotypes may not be easily obtained (e.g. multi-sample…

Genomics · Quantitative Biology 2013-03-19 Heng Li

In their 2008 and 2009 papers, Sumner and colleagues introduced the "squangles" - a small set of Markov invariants for phylogenetic quartets. The squangles are consistent with the general Markov model (GM) and can be used to infer quartets…

Quantitative Methods · Quantitative Biology 2012-04-24 Barbara R. Holland , Peter D. Jarvis , Jeremy G. Sumner