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Distributed Machine Learning (DML) on resource-constrained edge devices holds immense potential for real-world applications. However, achieving fast convergence in DML in these heterogeneous environments remains a significant challenge.…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-10 Advik Raj Basani , Siddharth Chaitra Vivek , Advaith Krishna , Arnab K. Paul

Confidence-based pseudo-label selection usually generates overly confident yet incorrect predictions, due to the early misleadingness of model and overfitting inaccurate pseudo-labels in the learning process, which heavily degrades the…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Peng Zhang , Zhihui Lai , Heng Kong

Molecular representation learning is pivotal in predicting molecular properties and advancing drug design. Traditional methodologies, which predominantly rely on homogeneous graph encoding, are limited by their inability to integrate…

Machine Learning · Computer Science 2025-03-24 Mukun Chen , Jia Wu , Shirui Pan , Fu Lin , Bo Du , Xiuwen Gong , Wenbin Hu

With the advent of high-throughput sequencing (HTS) in molecular biology and medicine, the need for scalable statistical solutions for modeling complex biological systems has become of critical importance. The increasing number of platforms…

Molecular Networks · Quantitative Biology 2022-10-19 Fernando Palluzzi , Mario Grassi

Multimodal knowledge graphs (MMKGs) enrich traditional knowledge graphs (KGs) by incorporating diverse modalities such as images and text. multimodal knowledge graph completion (MMKGC) seeks to exploit these heterogeneous signals to infer…

Computation and Language · Computer Science 2025-08-12 Yongkang Xiao , Rui Zhang

Complementary and alternative medicine are commonly used concomitantly with conventional medications leading to adverse drug reactions and even fatality in some cases. Furthermore, the vast possibility of herb-drug interactions prevents…

Artificial Intelligence · Computer Science 2023-06-28 Andreia Martins , Eva Maia , Isabel Praça

Biases in automated clinical decision-making using Electronic Healthcare Records (EHR) impose significant disparities in patient care and treatment outcomes. Conventional approaches have primarily focused on bias mitigation strategies…

Artificial Intelligence · Computer Science 2024-12-03 Resmi Ramachandranpillai , Kishore Sampath , Ayaazuddin Mohammad , Malihe Alikhani

Drug discovery requires a tremendous amount of time and cost. Computational drug-target interaction prediction, a significant part of this process, can reduce these requirements by narrowing the search space for wet lab experiments. In this…

Biomolecules · Quantitative Biology 2025-05-27 Mohammad Molaee , Nasrollah Moghadam Charkari , Foad Ghaderi

Industry demands are growing for hyper-distributed applications that span from the cloud to the edge in domains such as smart manufacturing, transportation, and agriculture. Yet today's solutions struggle to meet these demands due to…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-10 Chinmaya Kumar Dehury , Lauri Lovén , Praveen Kumar Donta , Ilir Murturi , Schahram Dustdar

Motivation: Identifying drug-target interactions (DTIs) is a key step in drug repositioning. In recent years, the accumulation of a large number of genomics and pharmacology data has formed mass drug and target related heterogeneous…

Machine Learning · Computer Science 2022-10-19 Hongzhun Wang , Feng Huang , Wen Zhang

Recommender systems are designed to predict user preferences over collections of items. These systems process users' previous interactions to decide which items should be ranked higher to satisfy their desires. An ensemble recommender…

Information Retrieval · Computer Science 2023-06-23 Alireza Gharahighehi , Celine Vens , Konstantinos Pliakos

We propose a representation learning framework for medical diagnosis domain. It is based on heterogeneous network-based model of diagnostic data as well as modified metapath2vec algorithm for learning latent node representation. We compare…

Machine Learning · Computer Science 2020-01-24 Karol Antczak

Biomedical Knowledge Graphs (BKGs) integrate diverse datasets to elucidate complex relationships within the biomedical field. Effective link prediction on these graphs can uncover valuable connections, such as potential novel drug-disease…

Computation and Language · Computer Science 2025-07-01 Tien Dang , Viet Thanh Duy Nguyen , Minh Tuan Le , Truong-Son Hy

Estimating heterogeneous treatment effects is an important problem across many domains. In order to accurately estimate such treatment effects, one typically relies on data from observational studies or randomized experiments. Currently,…

Machine Learning · Statistics 2022-02-28 Tobias Hatt , Jeroen Berrevoets , Alicia Curth , Stefan Feuerriegel , Mihaela van der Schaar

Electronic Health Records (EHRs) have become increasingly popular to support clinical decision-making and healthcare in recent decades. EHRs usually contain heterogeneous information, such as structural data in tabular form and unstructured…

Machine Learning · Computer Science 2024-03-15 Hejie Cui , Xinyu Fang , Ran Xu , Xuan Kan , Joyce C. Ho , Carl Yang

Recent advancements in recommender systems have focused on integrating knowledge graphs (KGs) to leverage their auxiliary information. The core idea of KG-enhanced recommenders is to incorporate rich semantic information for more accurate…

Information Retrieval · Computer Science 2024-07-08 Darnbi Sakong , Viet Hung Vu , Thanh Trung Huynh , Phi Le Nguyen , Hongzhi Yin , Quoc Viet Hung Nguyen , Thanh Tam Nguyen

Learning electronic health records (EHRs) has received emerging attention because of its capability to facilitate accurate medical diagnosis. Since the EHRs contain enriched information specifying complex interactions between entities,…

Machine Learning · Computer Science 2024-08-15 Tsai Hor Chan , Guosheng Yin , Kyongtae Bae , Lequan Yu

Characterizing interactions between drugs is important to avoid potentially harmful combinations, to reduce off-target effects of treatments and to fight antibiotic resistant pathogens, among others. Here we present a network inference…

Molecular Networks · Quantitative Biology 2014-11-07 Roger Guimera , Marta Sales-Pardo

Metasurfaces have provided a novel and promising platform for the realization of compact and large-scale optical devices. The conventional metasurface design approach assumes periodic boundary conditions for each element, which is…

Detailed phenotype information is fundamental to accurate diagnosis and risk estimation of diseases. As a rich source of phenotype information, electronic health records (EHRs) promise to empower diagnostic variant interpretation. However,…

Machine Learning · Computer Science 2023-04-28 Shenghan Zhang , Haoxuan Li , Ruixiang Tang , Sirui Ding , Laila Rasmy , Degui Zhi , Na Zou , Xia Hu
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