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Conversational generative AI has demonstrated remarkable promise for empowering biomedical practitioners, but current investigations focus on unimodal text. Multimodal conversational AI has seen rapid progress by leveraging billions of…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Chunyuan Li , Cliff Wong , Sheng Zhang , Naoto Usuyama , Haotian Liu , Jianwei Yang , Tristan Naumann , Hoifung Poon , Jianfeng Gao

Large Vision-Language Models (LVLMs) have shown significant potential in assisting medical diagnosis by leveraging extensive biomedical datasets. However, the advancement of medical image understanding and reasoning critically depends on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Guohao Sun , Can Qin , Huazhu Fu , Linwei Wang , Zhiqiang Tao

Autoregressive models (ARMs) have long dominated the landscape of biomedical vision-language models (VLMs). Recently, masked diffusion models such as LLaDA have emerged as promising alternatives, yet their application in the biomedical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Xuanzhao Dong , Wenhui Zhu , Xiwen Chen , Zhipeng Wang , Peijie Qiu , Shao Tang , Xin Li , Yalin Wang

Recently, Multimodal Large Language Models (MLLMs) have demonstrated exceptional capabilities in visual understanding and reasoning across various vision-language tasks. However, we found that MLLMs cannot process effectively from…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Bangyan Li , Wenxuan Huang , Zhenkun Gao , Yeqiang Wang , Yunhang Shen , Jingzhong Lin , Ling You , Yuxiang Shen , Shaohui Lin , Wanli Ouyang , Yuling Sun

Accurate and efficient question-answering systems are essential for delivering high-quality patient care in the medical field. While Large Language Models (LLMs) have made remarkable strides across various domains, they continue to face…

Computation and Language · Computer Science 2025-01-22 Hang Yang , Hao Chen , Hui Guo , Yineng Chen , Ching-Sheng Lin , Shu Hu , Jinrong Hu , Xi Wu , Xin Wang

To advance biomedical vison-language model capabilities through scaling up, fine-tuning, and instruction tuning, develop vision-language models with improved performance in handling long text, explore strategies to efficiently adopt vision…

Artificial Intelligence · Computer Science 2025-05-26 Cheng Peng , Kai Zhang , Mengxian Lyu , Hongfang Liu , Lichao Sun , Yonghui Wu

$ $The synergy of language and vision models has given rise to Large Language and Vision Assistant models (LLVAs), designed to engage users in rich conversational experiences intertwined with image-based queries. These comprehensive…

Computer Vision and Pattern Recognition · Computer Science 2024-01-02 Ashhadul Islam , Md. Rafiul Biswas , Wajdi Zaghouani , Samir Brahim Belhaouari , Zubair Shah

Large language models (LLMs) have demonstrated immense capabilities in understanding textual data and are increasingly being adopted to help researchers accelerate scientific discovery through knowledge extraction (information retrieval),…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Robinson Umeike , Neil Getty , Fangfang Xia , Rick Stevens

Multimodal Large Language Model (MLLM) has recently garnered attention as a prominent research focus. By harnessing powerful LLM, it facilitates a transition of conversational generative AI from unimodal text to performing multimodal tasks.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Xuechen Guo , Wenhao Chai , Shi-Yan Li , Gaoang Wang

The rocketing prosperity of large language models (LLMs) in recent years has boosted the prevalence of vision-language models (VLMs) in the medical sector. In our online medical consultation scenario, a doctor responds to the texts and…

Vision-language models (VLMs) have recently shown promise in general-purpose reasoning tasks, yet their applicability to domain-specific scientific workflows remains largely unexplored. In this work, we evaluated a series of open-weight and…

Instrumentation and Methods for Astrophysics · Physics 2026-02-10 S. Riggi

Recently, large language models (LLMs) have taken the spotlight in natural language processing. Further, integrating LLMs with vision enables the users to explore emergent abilities with multimodal data. Visual language models (VLMs), such…

Computer Vision and Pattern Recognition · Computer Science 2024-02-23 Minh-Hao Van , Prateek Verma , Xintao Wu

Medical large vision-language models (LVLMs) have demonstrated promising performance across various single-image question answering (QA) benchmarks, yet their capability in processing multi-image clinical scenarios remains underexplored.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Xikai Yang , Juzheng Miao , Yuchen Yuan , Jiaze Wang , Qi Dou , Jinpeng Li , Pheng-Ann Heng

With the rapid growth of large language models (LLMs) and vision-language models (VLMs) in medicine, simply integrating clinical text and medical imaging does not guarantee reliable reasoning. Existing multimodal models often produce…

Artificial Intelligence · Computer Science 2025-12-29 Zelin Zang , Wenyi Gu , Siqi Ma , Dan Yang , Yue Shen , Zhu Zhang , Guohui Fan , Wing-Kuen Ling , Fuji Yang

Large multimodal models (LMMs) have demonstrated significant potential in providing innovative solutions for various biomedical tasks, including pathology analysis, radiology report generation, and biomedical assistance. However, the…

Machine Learning · Computer Science 2025-12-30 Dong Xue , Ziyao Shao , Zhaoyang Duan , Fangzhou Liu , Bing Li , Zhongheng Zhang

Recent breakthroughs in large language models (LLMs) offer unprecedented natural language understanding and generation capabilities. However, existing surveys on LLMs in biomedicine often focus on specific applications or model…

Vision-Language Models (VLMs) trained on web-scale corpora excel at natural image tasks and are increasingly repurposed for healthcare; however, their competence in medical tasks remains underexplored. We present a comprehensive evaluation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-21 Che Liu , Jiazhen Pan , Weixiang Shen , Wenjia Bai , Daniel Rueckert , Rossella Arcucci

In recent advancements, multimodal large language models (MLLMs) have been fine-tuned on specific medical image datasets to address medical visual question answering (Med-VQA) tasks. However, this common approach of task-specific…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Lai Wei , Wenkai Wang , Xiaoyu Shen , Yu Xie , Zhihao Fan , Xiaojin Zhang , Zhongyu Wei , Wei Chen

Medical image analysis is essential in modern healthcare. Deep learning has redirected research focus toward complex medical multimodal tasks, including report generation and visual question answering. Traditional task-specific models often…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Yiming Shi , Shaoshuai Yang , Xun Zhu , Haoyu Wang , Xiangling Fu , Miao Li , Ji Wu

State-of-the-art medical multi-modal LLMs (med-MLLMs), such as LLaVA-Med and BioMedGPT, primarily depend on scaling model size and data volume, with training driven largely by autoregressive objectives. However, we reveal that this approach…

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