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Deep generative models such as diffusion and flow matching are powerful machine learning tools capable of learning and sampling from high-dimensional distributions. They are particularly useful when the training data appears to be…

High Energy Physics - Phenomenology · Physics 2026-04-30 Zachary Bogorad , Ibrahim Elsharkawy , Yonatan Kahn , Andrew J. Larkoski , Noam Levi

Two dimensional (2D) materials have emerged as promising functional materials with many applications such as semiconductors and photovoltaics because of their unique optoelectronic properties. While several thousand 2D materials have been…

Materials Science · Physics 2020-12-18 Yuqi Song , Edirisuriya M. Dilanga Siriwardane , Yong Zhao , Jianjun Hu

Generative tasks about molecules, including but not limited to molecule generation, are crucial for drug discovery and material design, and have consistently attracted significant attention. In recent years, diffusion models have emerged as…

Machine Learning · Computer Science 2025-02-14 Liang Wang , Chao Song , Zhiyuan Liu , Yu Rong , Qiang Liu , Shu Wu , Liang Wang

The development of new materials typically involves a process of trial and error, guided by insights from past experimental and theoretical findings. The inverse design approach for soft-matter systems has the potential to optimize specific…

Recent methods have shown that pre-trained diffusion models can be fine-tuned to enable generative inverse rendering by learning image-conditioned noise-to-intrinsic mapping. Despite their remarkable progress, they struggle to robustly…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Rongjia Zheng , Qing Zhang , Chengjiang Long , Wei-Shi Zheng

Since their introduction, diffusion models have quickly become the prevailing approach to generative modeling in many domains. They can be interpreted as learning the gradients of a time-varying sequence of log-probability density…

A key problem in computational material science deals with understanding the effect of material distribution (i.e., microstructure) on material performance. The challenge is to synthesize microstructures, given a finite number of…

This article considers the generative modeling of the (mixed) states of quantum systems, and an approach based on denoising diffusion model is proposed. The key contribution is an algorithmic innovation that respects the physical nature of…

Quantum Physics · Physics 2024-05-28 Yuchen Zhu , Tianrong Chen , Evangelos A. Theodorou , Xie Chen , Molei Tao

The classical method of determining the atomic structure of complex molecules by analyzing diffraction patterns is currently undergoing drastic developments. Modern techniques for producing extremely bright and coherent X-ray lasers allow a…

Biomolecules · Quantitative Biology 2015-10-12 Tomas Ekeberg , Stefan Engblom , Jing Liu

We introduce MxDiffusion, a hybrid physics- and data-driven diffusion-based framework that enables efficient and highly accurate generation of photonic structures from target optical properties. The improved accuracy is achieved through a…

Optics · Physics 2026-02-20 Sujoy Mondal , Taehyuk Park , Sudipta Biswas , Alan X. Wang , Wenshan Cai

Synthesizing realistic microstructure images conditioned on processing parameters is crucial for understanding process-structure relationships in materials design. However, this task remains challenging due to limited training micrographs…

Materials Science · Physics 2025-11-21 Hoang Cuong Phan , Minh Tien Tran , Chihun Lee , Hoheok Kim , Sehyeok Oh , Dong-Kyu Kim , Ho Won Lee

Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

Finite element simulations are run by package design engineers to model design structures. The process is irreversible meaning every minute structural adjustment requires a fresh input parameter run. In this paper, the problem of modeling…

Computational Engineering, Finance, and Science · Computer Science 2026-02-26 Kart-Leong Lim , Rahul Dutta , Mihai Rotaru

Designing composite materials as per the application requirements is fundamentally a challenging and time consuming task. Here we report the development of a deep neural network based computational framework capable of solving the forward…

Materials Science · Physics 2022-09-14 Ashank , Soumen Chakravarty , Pranshu Garg , Ankit Kumar , Manish Agrawal , Prabhat K. Agnihotri

Large-scale generative models, such as text-to-image diffusion models, have garnered widespread attention across diverse domains due to their creative and high-fidelity image generation. Nonetheless, existing large-scale diffusion models…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Younghyun Kim , Geunmin Hwang , Junyu Zhang , Eunbyung Park

Large text-guided diffusion models, such as DALLE-2, are able to generate stunning photorealistic images given natural language descriptions. While such models are highly flexible, they struggle to understand the composition of certain…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Nan Liu , Shuang Li , Yilun Du , Antonio Torralba , Joshua B. Tenenbaum

Diffusion models are powerful tools for sampling from high-dimensional distributions by progressively transforming pure noise into structured data through a denoising process. When equipped with a guidance mechanism, these models can also…

Machine Learning · Computer Science 2026-05-04 Saeed Mohseni-Sehdeh , Walid Saad , Kei Sakaguchi , Tao Yu

Photonic crystals enable fine control over light propagation at the nanoscale, and thus play a central role in the development of photonic and quantum technologies. Photonic band diagrams (BDs) are a key tool to investigate light…

Deep generative models have garnered significant attention in low-level vision tasks due to their generative capabilities. Among them, diffusion model-based solutions, characterized by a forward diffusion process and a reverse denoising…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Chunming He , Yuqi Shen , Chengyu Fang , Fengyang Xiao , Longxiang Tang , Yulun Zhang , Wangmeng Zuo , Zhenhua Guo , Xiu Li

The geometric design of structures with optimized physical and chemical properties is one of the core topics in materials science. However, designing new functional materials is challenging due to the vast number of existing and the…

Optics · Physics 2025-07-17 Congcong Cui , Guangfeng Wei , Matthias Saba , Yuanyuan Cao , Lu Han
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