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The development of single-cell and spatial transcriptomics has revolutionized our capacity to investigate cellular properties, functions, and interactions in both cellular and spatial contexts. However, the analysis of single-cell and…

Genomics · Quantitative Biology 2024-12-09 Shuang Ge , Shuqing Sun , Huan Xu , Qiang Cheng , Zhixiang Ren

The techniques of deep learning have become the state of the art methodology for executing complicated tasks from various domains of computer vision, natural language processing, and several other areas. Due to its rapid development and…

Machine Learning · Computer Science 2019-04-09 Rahul-Vigneswaran K , Prabaharan Poornachandran , Soman KP

Deep learning has become a popular tool for medical image analysis, but the limited availability of training data remains a major challenge, particularly in the medical field where data acquisition can be costly and subject to privacy…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Su Ruan

Molecules and materials are the foundation for the development of modern advanced industries such as energy storage systems and semiconductor devices. However, traditional trial-and-error methods or theoretical calculations are highly…

Machine learning techniques have been widely employed as effective tools in addressing various engineering challenges in recent years, particularly for the challenging task of microstructure-informed materials modeling. This work provides a…

Materials Science · Physics 2024-05-29 Xiang-Long Peng , Mozhdeh Fathidoost , Binbin Lin , Yangyiwei Yang , Bai-Xiang Xu

In biomedical applications of machine learning, relevant information often has a rich structure that is not easily encoded as real-valued predictors. Examples of such data include DNA or RNA sequences, gene sets or pathways, gene…

Genomics · Quantitative Biology 2019-10-16 Jake Crawford , Casey S. Greene

Biological networks provide insight into the complex organization of biological processes in a cell at the system level. They are an effective tool for understanding the comprehensive map of functional interactions, finding the functional…

Molecular Networks · Quantitative Biology 2017-09-14 Somaye Hashemifar

The field of deep learning has witnessed a remarkable shift towards extremely compute- and memory-intensive neural networks. These newer larger models have enabled researchers to advance state-of-the-art tools across a variety of fields.…

Machine Learning · Computer Science 2022-07-04 Daniel Nichols , Siddharth Singh , Shu-Huai Lin , Abhinav Bhatele

Deep learning research aims at discovering learning algorithms that discover multiple levels of distributed representations, with higher levels representing more abstract concepts. Although the study of deep learning has already led to…

Machine Learning · Computer Science 2013-06-10 Yoshua Bengio

Recent times are witnessing rapid development in machine learning algorithm systems, especially in reinforcement learning, natural language processing, computer and robot vision, image processing, speech, and emotional processing and…

Deep learning constitutes a recent, modern technique for image processing and data analysis, with promising results and large potential. As deep learning has been successfully applied in various domains, it has recently entered also the…

Machine Learning · Computer Science 2018-08-01 Andreas Kamilaris , Francesc X. Prenafeta-Boldu

Current pharmaceutical formulation development still strongly relies on the traditional trial-and-error approach by individual experiences of pharmaceutical scientists, which is laborious, time-consuming and costly. Recently, deep learning…

Machine Learning · Computer Science 2018-12-05 Yilong Yang , Zhuyifan Ye , Yan Su , Qianqian Zhao , Xiaoshan Li , Defang Ouyang

Deep convolutional neural networks (DCNNs) have become the state-of-the-art computational models of biological object recognition. Their remarkable success has helped vision science break new ground and recent efforts have started to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Leonard E. van Dyck , Walter R. Gruber

Topological Data Analysis (TDA) has emerged as a powerful framework for extracting robust, multiscale, and interpretable features from complex molecular data for artificial intelligence (AI) modeling and topological deep learning (TDL).…

Biomolecules · Quantitative Biology 2025-09-23 JunJie Wee , Jian Jiang

Machine learning (ML) empowers biomedical systems with the capability to optimize their performance through modeling of the available data extremely well, without using strong assumptions about the modeled system. Especially in nano-scale…

Inspired by key neuroscience principles, deep learning has driven exponential breakthroughs in developing functional models of perception and other cognitive processes. A key to this success has been the implementation of crucial features…

Neurons and Cognition · Quantitative Biology 2025-11-07 Guillaume Etter

Deep learning is a topic of considerable current interest. The availability of massive data collections and powerful software resources has led to an impressive amount of results in many application areas that reveal essential but hidden…

Machine Learning · Computer Science 2023-01-31 Gianluigi Pillonetto , Aleksandr Aravkin , Daniel Gedon , Lennart Ljung , Antônio H. Ribeiro , Thomas B. Schön

We provide an overview of the emergence of large language models for scientific computing applications. We highlight use cases that involve natural language processing of scientific documents and specialized languages designed to describe…

Computation and Language · Computer Science 2024-06-12 Christopher Culver , Peter Hicks , Mihailo Milenkovic , Sanjif Shanmugavelu , Tobias Becker

The past decade has seen a remarkable series of advances in machine learning, and in particular deep learning approaches based on artificial neural networks, to improve our abilities to build more accurate systems across a broad range of…

Machine Learning · Computer Science 2019-11-14 Jeffrey Dean

Molecular dynamics simulations are an important tool for describing the evolution of a chemical system with time. However, these simulations are inherently held back either by the prohibitive cost of accurate electronic structure theory…

Chemical Physics · Physics 2018-12-20 Michael Gastegger , Philipp Marquetand
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