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Melanoma is a fatal skin cancer that is curable and has dramatically increasing survival rate when diagnosed at early stages. Learning-based methods hold significant promise for the detection of melanoma from dermoscopic images. However,…
In hospitals, data are siloed to specific information systems that make the same information available under different modalities such as the different medical imaging exams the patient undergoes (CT scans, MRI, PET, Ultrasound, etc.) and…
The goal of this work is to develop principled techniques to extract information from high dimensional data sets with complex dependencies in areas such as medicine that can provide insight into individual as well as population level…
Finding well-defined clusters in data represents a fundamental challenge for many data-driven applications, and largely depends on good data representation. Drawing on literature regarding representation learning, studies suggest that one…
The capability of accurately determining code similarity is crucial in many tasks related to software development. For example, it might be essential to identify code duplicates for performing software maintenance. This research introduces…
Measuring dataset similarity is fundamental in machine learning, particularly for transfer learning and domain adaptation. In the context of supervised learning, most existing approaches quantify similarity of two data sets based on their…
The lack of well-annotated datasets in computational pathology (CPath) obstructs the application of deep learning techniques for classifying medical images. %Since pathologist time is expensive, dataset curation is intrinsically difficult.…
Datasets for biosignals, such as electroencephalogram (EEG) and electrocardiogram (ECG), often have noisy labels and have limited number of subjects (<100). To handle these challenges, we propose a self-supervised approach based on…
Missing covariate data commonly occur in epidemiological and clinical research, and are often dealt with using multiple imputation (MI). Imputation of partially observed covariates is complicated if the substantive model is non-linear (e.g.…
Code representation learning, which aims to encode the semantics of source code into distributed vectors, plays an important role in recent deep-learning-based models for code intelligence. Recently, many pre-trained language models for…
We present a new annotated microscopic cellular image dataset to improve the effectiveness of machine learning methods for cellular image analysis. Cell counting is an important step in cell analysis. Typically, domain experts manually…
The rapid finding of effective therapeutics requires the efficient use of available resources in clinical trials. The use of covariate adjustment can yield statistical estimates with improved precision, resulting in a reduction in the…
Reliable quantitative analysis of immunohistochemical staining images requires accurate and robust cell detection and classification. Recent weakly-supervised methods usually estimate probability density maps for cell recognition. However,…
The lack of labeled data is a major obstacle to learning high-quality sentence embeddings. Recently, self-supervised contrastive learning (SCL) is regarded as a promising way to address this problem. However, the existing works mainly rely…
Single-cell datasets often lack individual cell labels, making it challenging to identify cells associated with disease. To address this, we introduce Mixture Modeling for Multiple Instance Learning (MMIL), an expectation maximization…
In natural language processing and vision, pretraining is utilized to learn effective representations. Unfortunately, the success of pretraining does not easily carry over to time series due to potential mismatch between sources and target.…
Labeling of multivariate biomedical time series data is a laborious and expensive process. Self-supervised contrastive learning alleviates the need for large, labeled datasets through pretraining on unlabeled data. However, for multivariate…
Self-supervised learning methods based on data augmentations, such as SimCLR, BYOL, or DINO, allow obtaining semantically meaningful representations of image datasets and are widely used prior to supervised fine-tuning. A recent…
Background: Composite endpoints in cardiovascular trials combine heterogeneous outcomes-mortality, nonfatal events, hospitalizations, and biomarkers-yet conventional analytical methods sacrifice information by targeting a single dimension.…
Accurate cell detection and counting in the image-based ELISpot and FluoroSpot immunoassays is a challenging task. Recently proposed methodology matches human accuracy by leveraging knowledge of the underlying physical process of these…