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There has been an increasing focus in learning interpretable feature representations, particularly in applications such as medical image analysis that require explainability, whilst relying less on annotated data (since annotations can be…

Computer Vision and Pattern Recognition · Computer Science 2019-11-19 Gabriele Valvano , Agisilaos Chartsias , Andrea Leo , Sotirios A. Tsaftaris

With the perpetual increase of complexity of the state-of-the-art deep neural networks, it becomes a more and more challenging task to maintain their interpretability. Our work aims to evaluate the effects of adversarial training utilized…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Delyan Boychev

The success and generalisation of deep learning algorithms heavily depend on learning good feature representations. In medical imaging this entails representing anatomical information, as well as properties related to the specific imaging…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Agisilaos Chartsias , Thomas Joyce , Giorgos Papanastasiou , Scott Semple , Michelle Williams , David Newby , Rohan Dharmakumar , Sotirios A. Tsaftaris

As AI-based medical devices are becoming more common in imaging fields like radiology and histology, interpretability of the underlying predictive models is crucial to expand their use in clinical practice. Existing heatmap-based…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Kathryn Schutte , Olivier Moindrot , Paul Hérent , Jean-Baptiste Schiratti , Simon Jégou

Interpretability methods aim to help users build trust in and understand the capabilities of machine learning models. However, existing approaches often rely on abstract, complex visualizations that poorly map to the task at hand or require…

Human-Computer Interaction · Computer Science 2021-07-12 Harini Suresh , Kathleen M. Lewis , John V. Guttag , Arvind Satyanarayan

Understanding internal representations of neural models is a core interest of mechanistic interpretability. Due to its large dimensionality, the representation space can encode various aspects about inputs. To what extent are different…

Machine Learning · Computer Science 2026-05-15 Xinting Huang , Michael Hahn

We present a novel method for quantifying the microscopic structure of brain tissue. It is based on the automated recognition of interpretable features obtained by analyzing the shapes of cells. This contrasts with prevailing methods of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Kui Qian , Litao Qiao , Beth Friedman , Edward O'Donnell , David Kleinfeld , Yoav Freund

We propose a regularization scheme for image reconstruction that leverages the power of deep learning while hinging on classic sparsity-promoting models. Many deep-learning-based models are hard to interpret and cumbersome to analyze…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Mehrsa Pourya , Sebastian Neumayer , Michael Unser

Transformer-based models have become state-of-the-art tools in various machine learning tasks, including time series classification, yet their complexity makes understanding their internal decision-making challenging. Existing…

Machine Learning · Computer Science 2025-11-27 Matīss Kalnāre , Sofoklis Kitharidis , Thomas Bäck , Niki van Stein

Spatial transformations are enablers in a variety of medical image analysis applications that entail aligning images to a common coordinate systems. Population analysis of such transformations is expected to capture the underlying image and…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Riddhish Bhalodia , Shireen Y. Elhabian , Ladislav Kavan , Ross T. Whitaker

Recently, many neural network-based image compression methods have shown promising results superior to the existing tool-based conventional codecs. However, most of them are often trained as separate models for different target bit rates,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-09 Jooyoung Lee , Seyoon Jeong , Munchurl Kim

Variational Autoencoders (VAEs) are powerful generative models for learning latent representations. Standard VAEs generate dispersed and unstructured latent spaces by utilizing all dimensions, which limits their interpretability, especially…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Farshad Sangari Abiz , Reshad Hosseini , Babak N. Araabi

Sparse Autoencoders (SAEs) have shown promise in improving the interpretability of neural network activations, but can learn features that are not features of the input, limiting their effectiveness. We propose \textsc{Mutual Feature…

Machine Learning · Computer Science 2024-11-07 Luke Marks , Alasdair Paren , David Krueger , Fazl Barez

An important component of autoencoders is the method by which the information capacity of the latent representation is minimized or limited. In this work, the rank of the covariance matrix of the codes is implicitly minimized by relying on…

Machine Learning · Computer Science 2020-10-15 Li Jing , Jure Zbontar , Yann LeCun

One aim of dimensionality reduction is to discover the main factors that explain the data, and as such is paramount to many applications. When working with high dimensional data, autoencoders offer a simple yet effective approach to learn…

Machine Learning · Computer Science 2025-08-29 Benjamin Couéraud , Vikram Sunkara , Christof Schütte

Autoencoders can be challenged by spatially non-uniform sampling of image content. This is common in medical imaging, biology, and physics, where informative patterns occur rarely at specific image coordinates, as background dominates these…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Alejandro Castañeda Garcia , Jan van Gemert , Daan Brinks , Nergis Tömen

Electrocardiogram signals are omnipresent in medicine. A vital aspect in the analysis of this data is the identification and classification of heart beat types which is often done through automated algorithms. Advancements in neural…

Machine Learning · Computer Science 2019-11-13 Tom Van Steenkiste , Dirk Deschrijver , Tom Dhaene

State-of-the-art learned reconstruction methods often rely on black-box modules that, despite their strong performance, raise questions about their interpretability and robustness. Here, we build on a recently proposed image reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Joshua Schulz , David Schote , Christoph Kolbitsch , Kostas Papafitsoros , Andreas Kofler

Interpretable representations are the backbone of many explainers that target black-box predictive systems based on artificial intelligence and machine learning algorithms. They translate the low-level data representation necessary for good…

Machine Learning · Computer Science 2024-04-29 Kacper Sokol , Peter Flach

Reliable motion estimation and strain analysis using 3D+time echocardiography (4DE) for localization and characterization of myocardial injury is valuable for early detection and targeted interventions. However, motion estimation is…