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Accurate drug-target interaction (DTI) prediction is essential for computational drug discovery, yet existing models often rely on single-modality predefined molecular descriptors or sequence-based embeddings with limited…

As an essential element for the diagnosis and rehabilitation of psychiatric disorders, the electroencephalogram (EEG) based emotion recognition has achieved significant progress due to its high precision and reliability. However, one…

Machine Learning · Computer Science 2021-07-19 Hao Chen , Ming Jin , Zhunan Li , Cunhang Fan , Jinpeng Li , Huiguang He

Deep neural networks (DNNs), despite their impressive ability to generalize over-capacity networks, often rely heavily on malignant bias as shortcuts instead of task-related information for discriminative tasks. To address this problem,…

Machine Learning · Computer Science 2023-07-06 Yeonsung Jung , Hajin Shim , June Yong Yang , Eunho Yang

Unsupervised representation learning, particularly sequential disentanglement, aims to separate static and dynamic factors of variation in data without relying on labels. This remains a challenging problem, as existing approaches based on…

Machine Learning · Computer Science 2025-10-08 Hedi Zisling , Ilan Naiman , Nimrod Berman , Supasorn Suwajanakorn , Omri Azencot

Physiological signals such as electrocardiograms (ECG) and electroencephalograms (EEG) provide complementary insights into human health and cognition, yet multi-modal integration is challenging due to limited multi-modal labeled data, and…

The success of deep learning heavily depends on the availability of large labeled training sets. However, it is hard to get large labeled datasets in medical image domain because of the strict privacy concern and costly labeling efforts.…

Computer Vision and Pattern Recognition · Computer Science 2021-09-30 Dewen Zeng , Yawen Wu , Xinrong Hu , Xiaowei Xu , Haiyun Yuan , Meiping Huang , Jian Zhuang , Jingtong Hu , Yiyu Shi

Traditional techniques for emotion recognition have focused on the facial expression analysis only, thus providing limited ability to encode context that comprehensively represents the emotional responses. We present deep networks for…

Computer Vision and Pattern Recognition · Computer Science 2019-08-19 Jiyoung Lee , Seungryong Kim , Sunok Kim , Jungin Park , Kwanghoon Sohn

Automatic affect recognition is a challenging task due to the various modalities emotions can be expressed with. Applications can be found in many domains including multimedia retrieval and human computer interaction. In recent years, deep…

Computer Vision and Pattern Recognition · Computer Science 2018-02-14 Panagiotis Tzirakis , George Trigeorgis , Mihalis A. Nicolaou , Björn Schuller , Stefanos Zafeiriou

Contrastive Learning (CL) has emerged as a powerful method for training feature extraction models using unlabeled data. Recent studies suggest that incorporating a linear projection head post-backbone significantly enhances model…

Machine Learning · Computer Science 2024-10-08 Huanran Li , Daniel Pimentel-Alarcón

This paper presents a novel approach to processing multimodal data for dynamic emotion recognition, named as the Multimodal Masked Autoencoder for Dynamic Emotion Recognition (MultiMAE-DER). The MultiMAE-DER leverages the closely correlated…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Peihao Xiang , Chaohao Lin , Kaida Wu , Ou Bai

Subject-independent EEG emotion recognition is challenged by pronounced inter-subject variability and the difficulty of learning robust representations from short, noisy recordings. To address this, we propose a fusion framework that…

Machine Learning · Computer Science 2026-01-14 Zheng Zhou , Isabella McEvoy , Camilo E. Valderrama

In response to the COVID-19 pandemic, traditional physical classrooms have transitioned to online environments, necessitating effective strategies to ensure sustained student engagement. A significant challenge in online teaching is the…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Rekha R Nair , Tina Babu , Pavithra K

Electroencephalographic (EEG) signals have long been applied in the field of affective brain-computer interfaces (aBCIs). Cross-subject EEG-based emotion recognition has demonstrated significant potential in practical applications due to…

Machine Learning · Computer Science 2025-12-23 Yici Liu , Qi Wei Oung , Hoi Leong Lee

Classification of sleep stages is essential for assessing sleep quality and diagnosing sleep disorders. However, manual inspection of EEG characteristics for each stage is time-consuming and prone to human error. Although machine learning…

In deep learning for drug discovery, chemical data are often represented as simplified molecular-input line-entry system (SMILES) sequences which allow for straightforward implementation of natural language processing methodologies, one…

Machine Learning · Computer Science 2023-10-05 Kathryn E. Kirchoff , Travis Maxfield , Alexander Tropsha , Shawn M. Gomez

In recent years, the use of bio-sensing signals such as electroencephalogram (EEG), electrocardiogram (ECG), etc. have garnered interest towards applications in affective computing. The parallel trend of deep-learning has led to a huge leap…

Machine Learning · Computer Science 2019-05-20 Siddharth Siddharth , Tzyy-Ping Jung , Terrence J. Sejnowski

Current models on Explainable Artificial Intelligence (XAI) have shown an evident and quantified lack of reliability for measuring feature-relevance when statistically entangled features are proposed for training deep classifiers. There has…

Signal Processing · Electrical Eng. & Systems 2023-02-27 Juan Manuel Mayor-Torres , Sara Medina-DeVilliers , Tessa Clarkson , Matthew D. Lerner , Giuseppe Riccardi

Visual Emotion Recognition (VER) is a critical yet challenging task aimed at inferring emotional states of individuals based on visual cues. However, existing works focus on single domains, e.g., realistic images or stickers, limiting VER…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Wen Yin , Yong Wang , Guiduo Duan , Dongyang Zhang , Xin Hu , Yuan-Fang Li , Tao He

Emotion recognition based on electroencephalography (EEG) holds significant promise for affective brain-computer interfaces (aBCIs). However, its practical deployment faces challenges due to the variability within inter-subject and the…

Human-Computer Interaction · Computer Science 2025-09-25 Jiahao Tang , Youjun Li , Xiangting Fan , Yangxuan Zheng , Siyuan Lu , Xueping Li , Peng Fang , Chenxi Li , Zi-Gang Huang

Medical time series data, such as EEG and ECG, are vital for diagnosing neurological and cardiovascular diseases. However, their precise interpretation faces significant challenges due to high annotation costs, leading to data scarcity, and…

Machine Learning · Computer Science 2026-01-13 Kaito Tanaka , Aya Nakayama , Masato Ito , Yuji Nishimura , Keisuke Matsuda